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This gene belongs to the transport and Golgi organization family, whose members are predicted to play roles in secretory protein loading in the endoplasmic reticulum. Depletion of this gene in Drosophila S2 cells causes fusion of the Golgi with the ER. In mouse tissue culture cells, this protein co-localizes with a mitochondrially targeted mCherry protein and displays very low levels of co-localization with Golgi and peroxisomes. Allelic variants of this gene are associated with rhabdomyolysis, metabolic crises with encephalopathy, and cardiac arrhythmia.
C17H22orf25; C22orf25; C26H22orf25; D16H22S680E; DKFZP761P1121 protein; hypothetical protein DKFZp761P1121; MECRCN; RGD1310348; ser/Thr-rich protein T10 in DGCR region; T10; TANGO2; transport and golgi organization 2; transport and golgi organization 2 homolog; transport and golgi organization 2 homolog (Drosophila); transport and Golgi organization protein 2 homolog; Uncharacterized protein C22orf25; uncharacterized protein C22orf25 homolog; wu:fj48d05; zgc:100952
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