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Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.
MGC119154; MGC119155; T2R56; T2R60; TAS2R60; taste 2 receptor member 60; taste receptor type 2 member 56; Taste receptor type 2 member 60; taste receptor, type 2, member 60
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100 µL
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100 µL
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