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WNK is a serine/threonine kinase that plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Also, acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D, and SGK1. WNK localizes to a segment of kidney involved in salt, potassium, and pH homeostasis, the distal nephron. Mutations in the WNK gene result in Pseudohypaldosteronism and Neuropathy.
9430070M15Rik; SAZD; Tbl3; transducin (beta)-like 3; transducin beta like 3; transducin beta-like 3; transducin beta-like protein 3; UTP13; WD repeat-containing protein SAZD; WD-repeat protein SAZD
100 µL
100 µL
10 µL
100 µL
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