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This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure.
AU019250; D1Ertd754e; dJ747L4.1; si:ch211-155d24.2; T-box 19; T-box factor, pituitary; T-box protein 19; T-box transcription factor 19; T-box transcription factor TBX19; T-box transcription factor TBX19; T-box-containing protein TBXT; TBS 19; TBS19; TBX19; tbx-19; Tpit; Tpit; Tbx19
100 µL
100 µL
100 µL
100 µg
100 µg
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