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This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.
AW208754; D22S676; D22S750; II; macrocytic anemia; TC; TC II; TC TC D22S676; Tc2; TC-2; TCII; Tcn2; Tcn-2; Tcn2p; transcobalamin; transcobalamin 2; transcobalamin II; transcobalamin II precursor; transcobalamin II; macrocytic anemia; transcobalamin-2; vitamin B12-binding protein 2
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