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The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
6430529J03Rik; AR7; avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 1; AW259572; cerbA protein; c-erb-A protein; c-erb-A thyroid hormone receptor; c-ERBA-1; cerbAalpha; c-erbAalpha; c-erbA-alpha; c-erbAalpha2; c-erbA-alpha2; c-erbAalpha2; thyroid hormone receptor alpha; CHNG6; E ERB-T-1; EAR7; EAR-7; ERBA; ERBA ALPHA; ERBA related 7; ERBA1; ERBA-related 7; ERB-T-1; MGC000261; MGC43240; NR1A1; Nuclear receptor subfamily 1 group A member 1; Oncogene ERBA; Rvr; T3R[a]; T3Ralpha; Thra; THRA1; THRA2; Thyroid hormone receptor alpha; thyroid hormone receptor alpha 1; thyroid hormone receptor alpha 1 (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 1 formerly ERBA1); thyroid hormone receptor alpha 2; thyroid hormone receptor beta; thyroid hormone receptor, alpha; thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian); thyroid normone nuclear receptor alpha variant 1; TR; TR alpha 1; TR alpha 1+2; TR alpha 2; triiodothyronine receptor; unnamed protein product; V-erbA-related protein 7
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