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Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1), ZO1-like (see TJP1), p55-like (see MPP1), and LIN2-like (see CASK), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001).
CH474011:EDL88200; Dlgh4; Dlgh4 protein; Fibroblast growth factor-inducible protein 15; MAGUK p55 subfamily member 6; MAGUK protein p55T; membrane palmitoylated protein 6; membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 6); membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6); Mpp6; P55t; P55T protein; Pals2; protein associated with Lin7 2; protein associated with Lin-7 2; VAM1; VAM-1; VELI-associated MAGUK 1
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