Invitrogen

TNF alpha Monoclonal Antibody (MAb11), FITC, eBioscience™

TNF alpha Antibody in Flow Cytometry (Flow)

FIGURE: 1 / 25

TNF alpha Antibody (11-7349-82) in Flow

Normal human blood peripheral cells were stimulated with PMA/Ionomycin in the presence of Brefeldin A (Product # 00-4506-51) for 6 hours. Unstimulated (left) or stimulated (right) cells were surface stained with Anti-Human CD3 PE (Product # 12-0038-42) and intracellularly stained with Anti-Human TNF alpha FITC.

TNF alpha Antibody in Flow Cytometry, Neutralization (Flow, Neu)

TNF alpha Antibody in Immunohistochemistry (IHC)

Product Image Gallery

Product Details

11-7349-82

Applications

Tested Dilution

Publications

Western Blot (WB)

View 1 publication 1 publication

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Flow Cytometry (Flow)

1 µg/test

View 29 publications 29 publications

Neutralization (Neu)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse, Rhesus monkey

Host/Isotype

Mouse / IgG1, kappa

Recommended Isotype Control

Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), FITC, eBioscience™

Class

Monoclonal

Type

Antibody

Clone

MAb11

Conjugate

FITC FITC FITC

Excitation/Emission Max

498/517 nm View spectra

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

0.09% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_465424

Product Specific Information

Description: The MAb11 antibody reacts with human tumor necrosis factor-alpha (TNF alpha), a 17 kDa cytokine produced by monocytes, macrophages, neutrophils, NK cells and CD4+ T cells. TN alpha has cytolytic activity against a range of tumor cells and is important in immune regulation. TNF alpha forms dimers and trimers and also exists as a 26 kDa membrane bound form. The MAb11 antibody is a neutralizing antibody.

Applications Reported:Mab11 has been reported for use in intracellular flow cytometric analysis.

Applications Tested: Has been tested by intracellular staining and flow cytometric analysis of stimulated human peripheral blood cells. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.

Filtration: 0.2 µm post-manufacturing filtered.

Target Information

TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions. Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice. Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors. TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Product References

R274X-mutated Phf6 increased the self-renewal and skewed T cell differentiation of hematopoietic stem cells.

iScience

Lan Y,Yuan S,Guo T,Hou S,Zhao F,Yang W,Cao Y,Chu Y,Jiang E,Yuan W,Wang X

11-7349-82 was used in Flow Cytometry to demonstrate that Phf6R274X plays a critical role in fine-tuning T cells and HSC homeostasis.

Fri Jun 16 00:00:00 EDT 2023

R274X-mutated Phf6 increased the self-renewal and skewed T cell differentiation of hematopoietic stem cells.

iScience

Lan Y,Yuan S,Guo T,Hou S,Zhao F,Yang W,Cao Y,Chu Y,Jiang E,Yuan W,Wang X

11-7349-82 was used in Flow Cytometry to demonstrate that Phf6R274X plays a critical role in fine-tuning T cells and HSC homeostasis.

Fri Jun 16 00:00:00 EDT 2023

LINC01123 promotes immune escape by sponging miR-214-3p to regulate B7-H3 in head and neck squamous-cell carcinoma.

Cell death & disease

Li H,Yang Z,Yang X,Zhang F,Wang J,Wu Z,Wanyan C,Meng Q,Gao W,Yang X,Wei J

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Thu Feb 03 00:00:00 EST 2022

PRDM1/BLIMP1 induces cancer immune evasion by modulating the USP22-SPI1-PD-L1 axis in hepatocellular carcinoma cells.

Nature communications

Li Q,Zhang L,You W,Xu J,Dai J,Hua D,Zhang R,Yao F,Zhou S,Huang W,Dai Y,Zhang Y,Baheti T,Qian X,Pu L,Xu J,Xia Y,Zhang C,Tang J,Wang X

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Mon Dec 12 00:00:00 EST 2022

Enhanced antibody responses in fully vaccinated individuals against pan-SARS-CoV-2 variants following Omicron breakthrough infection.

Cell reports. Medicine

Jeong HW,Kim SM,Jung MK,Noh JY,Yoo JS,Kim EH,Kim YI,Yu K,Jang SG,Gil J,Casel MA,Rare R,Choi JH,Kim HS,Kim JH,Um J,Kim C,Kim Y,Chin BS,Jung S,Choi JY,Song KH,Kim YD,Park JS,Song JY,Shin EC,Choi YK

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Tue Oct 18 00:00:00 EDT 2022

Transcriptional correlates of malaria in RTS,S/AS01-vaccinated African children: a matched case-control study.

eLife

Moncunill G,Carnes J,Chad Young W,Carpp L,De Rosa S,Campo JJ,Nhabomba A,Mpina M,Jairoce C,Finak G,Haas P,Muriel C,Van P,Sanz H,Dutta S,Mordmüller B,Agnandji ST,Díez-Padrisa N,Williams NA,Aponte JJ,Valim C,Neafsey DE,Daubenberger C,McElrath MJ,Dobaño C,Stuart K,Gottardo R

11-7349-82 was used in Flow cytometry/Cell sorting to understand RTS,S/AS01-induced immune responses associated with vaccine protection.

Fri Jan 21 00:00:00 EST 2022

Primary exposure to SARS-CoV-2 variants elicits convergent epitope specificities, immunoglobulin V gene usage and public B cell clones.

Nature communications

Lima NS,Musayev M,Johnston TS,Wagner DA,Henry AR,Wang L,Yang ES,Zhang Y,Birungi K,Black WP,O'Dell S,Schmidt SD,Moon D,Lorang CG,Zhao B,Chen M,Boswell KL,Roberts-Torres J,Davis RL,Peyton L,Narpala SR,O'Connell S,Serebryannyy L,Wang J,Schrager A,Talana CA,Shimberg G,Leung K,Shi W,Khashab R,Biber A,Zilberman T,Rhein J,Vetter S,Ahmed A,Novik L,Widge A,Gordon I,Guech M,Teng IT,Phung E,Ruckwardt TJ,Pegu A,Misasi J,Doria-Rose NA,Gaudinski M,Koup RA,Kwong PD,McDermott AB,Amit S,Schacker TW,Levy I,Mascola JR,Sullivan NJ,Schramm CA,Douek DC

11-7349-82 was used in Immunocytochemistry to develop a method to obtain immunoglobulin sequences with concurrent rapid production and functional assessment of monoclonal antibodies from hundreds of single B cells sorted by flow cytometry.

Wed Dec 14 00:00:00 EST 2022

Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques.

Cell

Hoang TN,Pino M,Boddapati AK,Viox EG,Starke CE,Upadhyay AA,Gumber S,Nekorchuk M,Busman-Sahay K,Strongin Z,Harper JL,Tharp GK,Pellegrini KL,Kirejczyk S,Zandi K,Tao S,Horton TR,Beagle EN,Mahar EA,Lee MYH,Cohen J,Jean SM,Wood JS,Connor-Stroud F,Stammen RL,Delmas OM,Wang S,Cooney KA,Sayegh MN,Wang L,Filev PD,Weiskopf D,Silvestri G,Waggoner J,Piantadosi A,Kasturi SP,Al-Shakhshir H,Ribeiro SP,Sekaly RP,Levit RD,Estes JD,Vanderford TH,Schinazi RF,Bosinger SE,Paiardini M

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Thu Jan 21 00:00:00 EST 2021

Membrane lymphotoxin-α₂β is a novel tumor necrosis factor (TNF) receptor 2 (TNFR2) agonist.

Cell death & disease

Kucka K,Lang I,Zhang T,Siegmund D,Medler J,Wajant H

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Tue Apr 06 00:00:00 EDT 2021

NKD2 mediates stimulation-dependent ORAI1 trafficking to augment Ca²⁺ entry in T cells.

Cell reports

Wu B,Woo JS,Vila P,Jew M,Leung J,Sun Z,Srikanth S,Gwack Y

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Tue Aug 24 00:00:00 EDT 2021

Development of an Inflammatory CD14⁺ Dendritic Cell Subset in Humanized Mice.

Frontiers in immunology

Iwabuchi R,Ide K,Terahara K,Wagatsuma R,Iwaki R,Matsunaga H,Tsunetsugu-Yokota Y,Takeyama H,Takahashi Y

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Mon Sep 27 00:00:00 EDT 2021

Rejuvenating Effector/Exhausted CAR T Cells to Stem Cell Memory-Like CAR T Cells By Resting Them in the Presence of CXCL12 and the NOTCH Ligand.

Cancer research communications

Ando M,Kondo T,Tomisato W,Ito M,Shichino S,Srirat T,Mise-Omata S,Nakagawara K,Yoshimura A

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Fri Oct 01 00:00:00 EDT 2021

Inhibition of Cholesterol Esterification Enzyme Enhances the Potency of Human Chimeric Antigen Receptor T Cells against Pancreatic Carcinoma.

Molecular therapy oncolytics

Zhao L,Liu Y,Zhao F,Jin Y,Feng J,Geng R,Sun J,Kang L,Yu L,Wei Y

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Fri Mar 27 00:00:00 EDT 2020

Abrogation of HLA surface expression using CRISPR/Cas9 genome editing: a step toward universal T cell therapy.

Scientific reports

Lee J,Sheen JH,Lim O,Lee Y,Ryu J,Shin D,Kim YY,Kim M

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Tue Oct 20 00:00:00 EDT 2020

Ghrelin ameliorates tumor-induced adipose tissue atrophy and inflammation via Ghrelin receptor-dependent and -independent pathways.

Oncotarget

Liu H,Luo J,Guillory B,Chen JA,Zang P,Yoeli JK,Hernandez Y,Lee II,Anderson B,Storie M,Tewnion A,Garcia JM

11-7349 was used in Immunohistochemistry to characterize the pathways involved in AT atrophy in the Lewis Lung Carcinoma (LLC)-induced cachexia model and those mediating the effects of ghrelin in Ghsr +/+ and Ghsr -/- mice.

Tue Sep 01 00:00:00 EDT 2020

Ghrelin ameliorates tumor-induced adipose tissue atrophy and inflammation via Ghrelin receptor-dependent and -independent pathways.

Oncotarget

Liu H,Luo J,Guillory B,Chen JA,Zang P,Yoeli JK,Hernandez Y,Lee II,Anderson B,Storie M,Tewnion A,Garcia JM

Tue Sep 01 00:00:00 EDT 2020

Mucosal-associated invariant T (MAIT) cells mediate protective host responses in sepsis.

eLife

Trivedi S,Labuz D,Anderson CP,Araujo CV,Blair A,Middleton EA,Jensen O,Tran A,Mulvey MA,Campbell RA,Hale JS,Rondina MT,Leung DT

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Mon Nov 09 00:00:00 EST 2020

CAIX Regulates GBM Motility and TAM Adhesion and Polarization through EGFR/STAT3 under Hypoxic Conditions.

International journal of molecular sciences

Huang BR,Liu YS,Lai SW,Lin HJ,Shen CK,Yang LY,Lu DY

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Fri Aug 14 00:00:00 EDT 2020

Siglec-9 Regulates an Effector Memory CD8⁺ T-cell Subset That Congregates in the Melanoma Tumor Microenvironment.

Cancer immunology research

Haas Q,Boligan KF,Jandus C,Schneider C,Simillion C,Stanczak MA,Haubitz M,Seyed Jafari SM,Zippelius A,Baerlocher GM,Läubli H,Hunger RE,Romero P,Simon HU,von Gunten S

11-7349 was used in Flow cytometry/Cell sorting to demonstrate cytotoxic CD8+ T cells in melanoma intratumoral blood express Siglec-9.

Wed May 01 00:00:00 EDT 2019

Exhaustion of the CD8⁺ T Cell Compartment in Patients with Mutations in Phosphoinositide 3-Kinase Delta.

Frontiers in immunology

Wentink MWJ,Mueller YM,Dalm VASH,Driessen GJ,van Hagen PM,van Montfrans JM,van der Burg M,Katsikis PD

11-7349 was used in Flow cytometry/Cell sorting to study exhaustion of the CD8+ T cell compartment in activated phosphoinositide 3-kinase delta syndrome patients and compare them with healthy controls and HIV patients.

Mon Jun 24 00:00:00 EDT 2019

Heterogeneous Tumor-Immune Microenvironments among Differentially Growing Metastases in an Ovarian Cancer Patient.

Cell

Jiménez-Sánchez A,Memon D,Pourpe S,Veeraraghavan H,Li Y,Vargas HA,Gill MB,Park KJ,Zivanovic O,Konner J,Ricca J,Zamarin D,Walther T,Aghajanian C,Wolchok JD,Sala E,Merghoub T,Snyder A,Miller ML

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Thu Aug 24 00:00:00 EDT 2017

The distribution and function of human memory T cell subsets in lung cancer.

Immunologic research

Sheng SY,Gu Y,Lu CG,Zou JY,Hong H,Wang R

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Thu Jun 01 00:00:00 EDT 2017

Application of a whole blood mycobacterial growth inhibition assay to study immunity against Mycobacterium tuberculosis in a high tuberculosis burden population.

PloS one

Baguma R,Penn-Nicholson A,Smit E,Erasmus M,Day J,Makhethe L,de Kock M,Hughes EJ,van Rooyen M,Pienaar B,Stone L,Hanekom W,Brennan MJ,Wallis RS,Hatherill M,Scriba TJ

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Wed Oct 18 00:00:00 EDT 2017

High pathogen burden in childhood promotes the development of unconventional innate-like CD8+ T cells.

JCI insight

Falanga YT,Frascoli M,Kaymaz Y,Forconi C,Ong'echa JM,Bailey JA,Berg LJ,Moormann AM

11-7349 was used in Flow cytometry/Cell sorting to suggest that the unconventional CD8dim T cells arise in a very particular immunological context and may provide a deeper understanding of the heterogeneity in human immune responses.

Thu Aug 03 00:00:00 EDT 2017

Compartment-specific immunity in the human gut: properties and functions of dendritic cells in the colon versus the ileum.

Gut

Mann ER,Bernardo D,English NR,Landy J,Al-Hassi HO,Peake ST,Man R,Elliott TR,Spranger H,Lee GH,Parian A,Brant SR,Lazarev M,Hart AL,Li X,Knight SC

11-7349 was used in Flow cytometry/Cell sorting to investigate and distinguish properties of dendritic cells in the colon and the ileum.

Mon Feb 01 00:00:00 EST 2016

Human Infant Memory B Cell and CD4+ T Cell Responses to HibMenCY-TT Glyco-Conjugate Vaccine.

PloS one

Fuery A,Richmond PC,Currie AJ

11-7349 was used in Flow cytometry/Cell sorting to demonstrate that Men C-specific memory B cells present pre-boost are influential in secondary IgG responses to HibMenCY-TT vaccine.

Thu Apr 28 00:00:00 EDT 2016

Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.

Science signaling

Kusne Y,Carrera-Silva EA,Perry AS,Rushing EJ,Mandell EK,Dietrich JD,Errasti AE,Gibbs D,Berens ME,Loftus JC,Hulme C,Yang W,Lu Z,Aldape K,Sanai N,Rothlin CV,Ghosh S

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Tue Aug 12 00:00:00 EDT 2014

Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.

Science signaling

Kusne Y,Carrera-Silva EA,Perry AS,Rushing EJ,Mandell EK,Dietrich JD,Errasti AE,Gibbs D,Berens ME,Loftus JC,Hulme C,Yang W,Lu Z,Aldape K,Sanai N,Rothlin CV,Ghosh S

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Tue Aug 12 00:00:00 EDT 2014

Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.

Science signaling

Kusne Y,Carrera-Silva EA,Perry AS,Rushing EJ,Mandell EK,Dietrich JD,Errasti AE,Gibbs D,Berens ME,Loftus JC,Hulme C,Yang W,Lu Z,Aldape K,Sanai N,Rothlin CV,Ghosh S

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Tue Aug 12 00:00:00 EDT 2014

Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.

Science signaling

Kusne Y,Carrera-Silva EA,Perry AS,Rushing EJ,Mandell EK,Dietrich JD,Errasti AE,Gibbs D,Berens ME,Loftus JC,Hulme C,Yang W,Lu Z,Aldape K,Sanai N,Rothlin CV,Ghosh S

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Tue Aug 12 00:00:00 EDT 2014

Attenuation of natural killer cell functions by capsaicin through a direct and TRPV1-independent mechanism.

Carcinogenesis

Kim HS,Kwon HJ,Kim GE,Cho MH,Yoon SY,Davies AJ,Oh SB,Lee H,Cho YK,Joo CH,Kwon SW,Kim SC,Kim YK

11-7349 was used in Flow cytometry/Cell sorting to demonstrate that capsaicin inhibits NK cell-mediated cytotoxicity and cytokine production (interferon-γ and tumor necrosis factor-α).

Tue Jul 01 00:00:00 EDT 2014

Attenuation of natural killer cell functions by capsaicin through a direct and TRPV1-independent mechanism.

Carcinogenesis

Kim HS,Kwon HJ,Kim GE,Cho MH,Yoon SY,Davies AJ,Oh SB,Lee H,Cho YK,Joo CH,Kwon SW,Kim SC,Kim YK

11-7349 was used in Flow cytometry/Cell sorting to demonstrate that capsaicin inhibits NK cell-mediated cytotoxicity and cytokine production (interferon-γ and tumor necrosis factor-α).

Tue Jul 01 00:00:00 EDT 2014

Attenuation of natural killer cell functions by capsaicin through a direct and TRPV1-independent mechanism.

Carcinogenesis

Kim HS,Kwon HJ,Kim GE,Cho MH,Yoon SY,Davies AJ,Oh SB,Lee H,Cho YK,Joo CH,Kwon SW,Kim SC,Kim YK

11-7349 was used in Flow cytometry/Cell sorting to demonstrate that capsaicin inhibits NK cell-mediated cytotoxicity and cytokine production (interferon-γ and tumor necrosis factor-α).

Tue Jul 01 00:00:00 EDT 2014

Attenuation of natural killer cell functions by capsaicin through a direct and TRPV1-independent mechanism.

Carcinogenesis

Kim HS,Kwon HJ,Kim GE,Cho MH,Yoon SY,Davies AJ,Oh SB,Lee H,Cho YK,Joo CH,Kwon SW,Kim SC,Kim YK

11-7349 was used in Flow cytometry/Cell sorting to demonstrate that capsaicin inhibits NK cell-mediated cytotoxicity and cytokine production (interferon-γ and tumor necrosis factor-α).

Tue Jul 01 00:00:00 EDT 2014

Cell-mediated immune responses to respiratory syncytial virus infection: magnitude, kinetics, and correlates with morbidity and age.

Human vaccines & immunotherapeutics

Geevarghese B,Weinberg A

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Mon Apr 25 00:00:00 EDT 2016

Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset.

PLoS pathogens

Lindestam Arlehamn CS,Gerasimova A,Mele F,Henderson R,Swann J,Greenbaum JA,Kim Y,Sidney J,James EA,Taplitz R,McKinney DM,Kwok WW,Grey H,Sallusto F,Peters B,Sette A

11-7349 was used in Flow cytometry/Cell sorting to further define the immunological footprint of Mycobacterium tuberculosis CD4 T cell recognition.

Tue Jan 01 00:00:00 EST 2013

Functional OCT4-specific CD4⁺ and CD8⁺ T cells in healthy controls and ovarian cancer patients.

Oncoimmunology

Di J,Massuger LF,Duiveman-de Boer T,Zusterzeel PL,Figdor CG,Torensma R

Published figure using TNF alpha monoclonal antibody (Product # 11-7349-82) in Flow Cytometry

Wed May 01 00:00:00 EDT 2013

Expansion of polyfunctional HIV-specific T cells upon stimulation with mRNA electroporated dendritic cells in the presence of immunomodulatory drugs.

Journal of virology

De Keersmaecker B,Allard SD,Lacor P,Schots R,Thielemans K,Aerts JL

11-7349 was used in Immunofluorescence to provide new information about the effects of IMiDs on antigen-specific T cells and suggest that these drugs increase the efficacy of immune therapies for infectious diseases and cancer.

Sat Sep 01 00:00:00 EDT 2012

Durable mucosal simian immunodeficiency virus-specific effector memory T lymphocyte responses elicited by recombinant adenovirus vectors in rhesus monkeys.

Journal of virology

Li H,Liu J,Carville A,Mansfield KG,Lynch D,Barouch DH

11-7349 was used in Flow cytometry/Cell sorting to demonstrate that nonreplicating rAd vectors induce durable and widely distributed effector memory mucosal T lymphocyte responses.

Tue Nov 01 00:00:00 EDT 2011

Bioinformatics

Protein Aliases: APC1 protein; Cachectin; DADB-70P7.1; TNF alpha; TNF superfamily; TNF α; TNF, macrophage-derived; TNF, monocyte-derived; TNF-a; TNF-alpha; TNFα; Tumor necrosis factor; tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; tumor necrosis factor-alpha

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Gene Aliases: DIF; TNF; TNF-alpha; TNFA; TNFSF2; TNLG1F

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UniProt ID: (Human) P01375

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Entrez Gene ID: (Human) 7124

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Function(s)

protease binding cytokine activity tumor necrosis factor receptor binding protein binding identical protein binding transcription regulatory region DNA binding

Process(es)

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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TNF alpha Monoclonal Antibody (MAb11), FITC, eBioscience™

TNF alpha Antibody (11-7349-82) in Flow

Product Details

11-7349-82

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Neutralization (Neu)

Species Reactivity

Published species

Host/Isotype

Recommended Isotype Control

Class

Type

Clone

Conjugate

Excitation/Emission Max

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

How to use the Panel Builder

Bioinformatics

Performance Guarantee

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