Invitrogen

HLA-ABC Monoclonal Antibody (W6/32), FITC, eBioscience™

Advanced Verification

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

9 Published Figures

40 References

View all (73) HLA-ABC antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

HLA-ABC Antibody in Flow Cytometry (Flow)

FIGURE: 1 / 12

HLA-ABC Antibody (11-9983-42) in Flow

Staining of normal human peripheral blood cells with Mouse IgG2a K Isotype Control FITC (Product # 11-4724-42) (blue histogram) or Anti-Human HLA-ABC FITC (purple histogram). Cells in the lymphocyte gate were used for analysis.

HLA-ABC Antibody in Immunocytochemistry (ICC/IF)

HLA-ABC Antibody in Neutralization (Neu)

Product Image Gallery

Product Details

11-9983-42

Applications

Tested Dilution

Publications

Immunohistochemistry (Frozen) (IHC (F))

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

5 µg/mL

View 3 publications 3 publications

Flow Cytometry (Flow)

5 µL (1 µg)/test

View 34 publications 34 publications

Neutralization (Neu)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human, Rhesus monkey

Host/Isotype

Mouse / IgG2a, kappa

Recommended Isotype Control

Mouse IgG2a kappa Isotype Control (eBM2a), FITC, eBioscience™

Class

Monoclonal

Type

Antibody

Clone

W6/32

Conjugate

FITC FITC FITC

Excitation/Emission Max

498/517 nm View spectra

Form

Liquid

Concentration

5 µL/Test

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with 0.2% BSA

Contains

0.09% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1633402

Product Specific Information

Description: The W6/32 monoclonal antibody reacts with the human major histocompatibility complex (MHC) class I, HLA-A, B, C. MHC class I antigens associated with beta 2-microglobulin are expressed by all human nucleated cells and are central in cell-mediated immune response and tumor surveillance. W6/32 mAb recognizes a non-polymorphic epitope shared among products of the HLA-A, B, and C loci and immunoprecipitates both 43 kDa and 11-12 kDa chains. Crossreactivity is also seen in baboon, rhesus and cynomolgus monkey.

Applications Reported: The W6/32 antibody has been reported for use in flow cytometric analysis.

Applications Tested: This W6/32 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (1 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.

Filtration: 0.2 µm post-manufacturing filtered.

Target Information

HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumor defense. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.

HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Product References

Mesenchymal stem cells transfer mitochondria to allogeneic Tregs in an HLA-dependent manner improving their immunosuppressive activity.

Nature communications

Piekarska K,Urban-Wójciuk Z,Kurkowiak M,Pelikant-Małecka I,Schumacher A,Sakowska J,Spodnik JH,Arcimowicz Ł,Zielińska H,Tymoniuk B,Renkielska A,Siebert J,Słomińska E,Trzonkowski P,Hupp T,Marek-Trzonkowska NM

Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry

Mon Feb 14 00:00:00 EST 2022

Doxorubicin sensitizes breast cancer cells to natural killer cells in connection with increased Fas receptors.

International journal of molecular medicine

Sawasdee N,Wattanapanitch M,Thongsin N,Phanthaphol N,Chiawpanit C,Thuwajit C,Yenchitsomanus PT,Panya A

11-9983-42 was used in Flow Cytometry, Immunocytochemistry to support the use of combined doxorubicin and NK immunotherapy in BC treatment.

Tue Mar 01 00:00:00 EST 2022

Cancer genes disfavoring T cell immunity identified via integrated systems approach.

Cell reports

Kishton RJ,Patel SJ,Decker AE,Vodnala SK,Cam M,Yamamoto TN,Patel Y,Sukumar M,Yu Z,Ji M,Henning AN,Gurusamy D,Palmer DC,Stefanescu RA,Girvin AT,Lo W,Pasetto A,Malekzadeh P,Deniger DC,Wood KC,Sanjana NE,Restifo NP

11-9983-42 was used in Flow cytometry/Cell sorting to establish that BIRC2 limits antigen presentation and T cell recognition of tumor cells by suppressing IRF1 activity and provide evidence that BIRC2 inhibition in combination with Adoptive T cell therapies is an effective strategy to increase efficacy.

Tue Aug 02 00:00:00 EDT 2022

A Costimulatory CAR Improves TCR-based Cancer Immunotherapy.

Cancer immunology research

Omer B,Cardenas MG,Pfeiffer T,Daum R,Huynh M,Sharma S,Nouraee N,Xie C,Tat C,Perconti S,Van Pelt S,Scherer L,DeRenzo C,Shum T,Gottschalk S,Arber C,Rooney CM

11-9983-42 was used in Flow Cytometry, Immunocytochemistry to demonstrate that the CoCAR can increase the activity of T cells expressing both native and transgenic TCRs and enhance antitumor responses.

Fri Apr 01 00:00:00 EDT 2022

Mesenchymal stem cells negatively regulate CD4⁺ T cell activation in patients with primary Sjögren syndrome through the miRNA‑125b and miRNA‑155 TCR pathway.

Molecular medicine reports

Gong B,Zheng L,Lu Z,Huang J,Pu J,Pan S,Zhang M,Liu J,Tang J

11-9983 was used in Flow cytometry/Cell sorting to indicate that the expression levels of miRNA‚125b‚5p and miRNA‚155 in TCR‚activated CD4+ T cells from patients with pSS may provide insight regarding autoimmune diseases and offer a novel target for prospective treatment.

Fri Jan 01 00:00:00 EST 2021

Capturing T Lymphocytes' Dynamic Interactions With Human Neural Cells Using Time-Lapse Microscopy.

Frontiers in immunology

Lemaître F,Carmena Moratalla A,Farzam-Kia N,Carpentier Solorio Y,Tastet O,Cleret-Buhot A,Guimond JV,Haddad E,Arbour N

Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Neutralization

Wed Oct 20 00:00:00 EDT 2021

Frequent amplification of HDAC genes and efficacy of HDAC inhibitor chidamide and PD-1 blockade combination in soft tissue sarcoma.

Journal for immunotherapy of cancer

Que Y,Zhang XL,Liu ZX,Zhao JJ,Pan QZ,Wen XZ,Xiao W,Xu BS,Hong DC,Guo TH,Shen LJ,Fan WJ,Chen HY,Weng DS,Xu HR,Zhou PH,Zhang YZ,Niu XH,Zhang X

Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry

Mon Feb 01 00:00:00 EST 2021

Attenuation of Heparan Sulfate Proteoglycan Binding Enhances In Vivo Transduction of Human Primary Hepatocytes with AAV2.

Molecular therapy. Methods & clinical development

Cabanes-Creus M,Westhaus A,Navarro RG,Baltazar G,Zhu E,Amaya AK,Liao SHY,Scott S,Sallard E,Dilworth KL,Rybicki A,Drouyer M,Hallwirth CV,Bennett A,Santilli G,Thrasher AJ,Agbandje-McKenna M,Alexander IE,Lisowski L

Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry

Fri Jun 12 00:00:00 EDT 2020

TOPK is regulated by PP2A and BCR/ABL in leukemia and enhances cell proliferation.

International journal of oncology

Uchida E,Suwa S,Yoshimoto R,Watanabe K,Kasama T,Miura O,Fukuda T

11-9983 was used in Flow cytometry/Cell sorting to study the association between chronic myeloid leukemia (CML) and T-lymphokine-activated killer cell-originated protein kinase (TOPK).

Wed May 01 00:00:00 EDT 2019

High-yield isolation of menstrual blood-derived endometrial stem cells by direct red blood cell lysis treatment.

Biology open

Sun Y,Ren Y,Yang F,He Y,Liang S,Guan L,Cheng F,Liu Y,Lin J

11-9983 was used in Flow cytometry/Cell sorting to determine whether primary MenSCs exist in the sedimentation of the deciduous endometrium after DGC and further to evaluate the isolation of MenSCs by direct red blood cell lysis treatment.

Thu May 02 00:00:00 EDT 2019

High-yield isolation of menstrual blood-derived endometrial stem cells by direct red blood cell lysis treatment.

Biology open

Sun Y,Ren Y,Yang F,He Y,Liang S,Guan L,Cheng F,Liu Y,Lin J

Thu May 02 00:00:00 EDT 2019

Exploration of the Combination of PLK1 Inhibition with Immunotherapy in Cancer Treatment.

Journal of oncology

Li M,Liu Z,Wang X

Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry

Thu Mar 31 00:00:00 EDT 2022

Activated human primary NK cells efficiently kill colorectal cancer cells in 3D spheroid cultures irrespectively of the level of PD-L1 expression.

Oncoimmunology

Lanuza PM,Vigueras A,Olivan S,Prats AC,Costas S,Llamazares G,Sanchez-Martinez D,Ayuso JM,Fernandez L,Ochoa I,Pardo J

11-9983 was used in Flow cytometry/Cell sorting to study the impact of 3D growth on solid cancer immunotherapy.

Tue Jan 12 00:00:00 EST 2021

Role of Nuclear Factor (Erythroid-Derived 2)-Like 2 Signaling for Effects of Fumaric Acid Esters on Dendritic Cells.

Frontiers in immunology

Hammer A,Waschbisch A,Knippertz I,Zinser E,Berg J,Jörg S,Kuhbandner K,David C,Pi J,Bayas A,Lee DH,Haghikia A,Gold R,Steinkasserer A,Linker RA

Wed Nov 20 00:00:00 EST 2019

Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells.

PloS one

Sethumadhavan S,Silva M,Philbrook P,Nguyen T,Hatfield SM,Ohta A,Sitkovsky MV

Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry

Wed Dec 06 00:00:00 EST 2017

Feasibility of placenta-derived mesenchymal stem cells as a tool for studying pregnancy-related disorders.

Scientific reports

Fuchi N,Miura K,Doi H,Li TS,Masuzaki H

11-9983 was used in Flow cytometry/Cell sorting to evaluate the feasibility of using placenta-derived mesenchymal stem cells as a tool to study pregnancy related disorders.

Wed Apr 12 00:00:00 EDT 2017

L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity.

Cell

Geiger R,Rieckmann JC,Wolf T,Basso C,Feng Y,Fuhrer T,Kogadeeva M,Picotti P,Meissner F,Mann M,Zamboni N,Sallusto F,Lanzavecchia A

11-9983 was used in Flow cytometry/Cell sorting to discover critical changes in the arginine metabolism that lead to a drop in intracellular L-arginine concentration, and characterise the effects in T cells.

Thu Oct 20 00:00:00 EDT 2016

Identification of the Cell-Intrinsic and -Extrinsic Pathways Downstream of EGFR and IFNγ That Induce PD-L1 Expression in Head and Neck Cancer.

Cancer research

Concha-Benavente F,Srivastava RM,Trivedi S,Lei Y,Chandran U,Seethala RR,Freeman GJ,Ferris RL

11-9983 was used in Flow cytometry/Cell sorting to investigate the mechanism by which EGFR and IFNγ upregulate PD-L1 expression in head and neck cancers cells, in the context of JAK/STAT pathway activation, Th1 inflammation, and HPV status.

Tue Mar 01 00:00:00 EST 2016

Identification and validation of multiple cell surface markers of clinical-grade adipose-derived mesenchymal stromal cells as novel release criteria for good manufacturing practice-compliant production.

Stem cell research & therapy

Camilleri ET,Gustafson MP,Dudakovic A,Riester SM,Garces CG,Paradise CR,Takai H,Karperien M,Cool S,Sampen HJ,Larson AN,Qu W,Smith J,Dietz AB,van Wijnen AJ

Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry

Thu Aug 11 00:00:00 EDT 2016

Blocking MHC class II on human endothelium mitigates acute rejection.

JCI insight

Abrahimi P,Qin L,Chang WG,Bothwell AL,Tellides G,Saltzman WM,Pober JS

11-9983 was used in Flow cytometry/Cell sorting to establish the immune cell network involved in acute allograft rejection in humans and identify targets for minimising this rejection.

Wed Nov 20 00:00:00 EST 2019

Efficient gene disruption in cultured primary human endothelial cells by CRISPR/Cas9.

Circulation research

Abrahimi P,Chang WG,Kluger MS,Qyang Y,Tellides G,Saltzman WM,Pober JS

11-9983 was used in Flow cytometry/Cell sorting to demonstrate that the CRISPR/Cas9 modification of epithelial cells is a powerful platform for vascular research and for regenerative medicine.

Fri Jul 03 00:00:00 EDT 2015

CD47 is an adverse prognostic factor and a therapeutic target in gastric cancer.

Cancer medicine

Yoshida K,Tsujimoto H,Matsumura K,Kinoshita M,Takahata R,Matsumoto Y,Hiraki S,Ono S,Seki S,Yamamoto J,Hase K

11-9983 was used in Flow cytometry/Cell sorting to demonstrate that higher expressions of CD44 and CD47 in gastric cancer cells correlate with higher proliferation and tumorigenicity.

Tue Sep 01 00:00:00 EDT 2015

Anti-angiogenic efficacy of 5'-triphosphate siRNA combining VEGF silencing and RIG-I activation in NSCLCs.

Oncotarget

Yuan D,Xia M,Meng G,Xu C,Song Y,Wei J

Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry

Tue Oct 06 00:00:00 EDT 2015

Anti-angiogenic efficacy of 5'-triphosphate siRNA combining VEGF silencing and RIG-I activation in NSCLCs.

Oncotarget

Yuan D,Xia M,Meng G,Xu C,Song Y,Wei J

Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry

Tue Oct 06 00:00:00 EDT 2015

Human NK cells activated by EBV⁺ lymphoblastoid cells overcome anti-apoptotic mechanisms of drug resistance in haematological cancer cells.

Oncoimmunology

Sánchez-Martínez D,Azaceta G,Muntasell A,Aguiló N,Núñez D,Gálvez EM,Naval J,Anel A,Palomera L,Vilches C,Marzo I,Villalba M,Pardo J

11-9983 was used in Flow cytometry/Cell sorting to demonstrate a novel mechanism for natural killer cells to overcome oncogenic alterations that allow haematological cancer cells to evade destruction.

Sun Mar 01 00:00:00 EST 2015

Multifunctional antitumor molecule 5'-triphosphate siRNA combining glutaminase silencing and RIG-I activation.

International journal of cancer

Meng G,Xia M,Xu C,Yuan D,Schnurr M,Wei J

Tue Apr 15 00:00:00 EDT 2014

Inhibition of mitogen-activated protein kinase pathway can induce upregulation of human leukocyte antigen class I without PD-L1-upregulation in contrast to interferon-γ treatment.

Cancer science

Mimura K,Kua LF,Shiraishi K,Kee Siang L,Shabbir A,Komachi M,Suzuki Y,Nakano T,Yong WP,So J,Kono K

11-9983 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which HLA class I and PD-L1 are regulated by MAPK inhibitors and interferon-γ.

Wed Oct 01 00:00:00 EDT 2014

Generation of functional, antigen-specific CD8+ human T cells from cord blood stem cells using exogenous Notch and tetramer-TCR signaling.

Stem cells (Dayton, Ohio)

Fernandez I,Ooi TP,Roy K

Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry

Wed Jan 01 00:00:00 EST 2014

IL-22 suppresses IFN-γ-mediated lung inflammation in asthmatic patients.

The Journal of allergy and clinical immunology

Pennino D,Bhavsar PK,Effner R,Avitabile S,Venn P,Quaranta M,Marzaioli V,Cifuentes L,Durham SR,Cavani A,Eyerich K,Chung KF,Schmidt-Weber CB,Eyerich S

11-9983 was used in Flow cytometry/Cell sorting to investigate the anti-inflammatory role for IL-22 in human asthma.

Fri Feb 01 00:00:00 EST 2013

HLA engineering of human pluripotent stem cells.

Molecular therapy : the journal of the American Society of Gene Therapy

Riolobos L,Hirata RK,Turtle CJ,Wang PR,Gornalusse GG,Zavajlevski M,Riddell SR,Russell DW

11-9983 was used in Flow cytometry/Cell sorting to develop two genetic engineering approaches to address the problem of rejection of transplanted cells due to differences in their human leukocyte antigen genes.

Sat Jun 01 00:00:00 EDT 2013

Methylglyoxal modulates immune responses: relevance to diabetes.

Journal of cellular and molecular medicine

Price CL,Hassi HO,English NR,Blakemore AI,Stagg AJ,Knight SC

11-9983 was used in Flow cytometry/Cell sorting to demonstrate that methylglyoxal blocks upregulation of the maturation marker CD83 on dendritic cells, and reduces their ability to stimulate T cells in allogeneic culture.

Tue Jun 01 00:00:00 EDT 2010

Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation.

PLoS genetics

Andrés AM,Dennis MY,Kretzschmar WW,Cannons JL,Lee-Lin SQ,Hurle B,Schwartzberg PL,Williamson SH,Bustamante CD,Nielsen R,Clark AG,Green ED

11-9983 was used in Flow cytometry/Cell sorting to study the haplotypes of ERAP2, a gene with a fundamental role in MHC class I presentation.

Thu Oct 14 00:00:00 EDT 2010

KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C.

The Journal of experimental medicine

Graef T,Moesta AK,Norman PJ,Abi-Rached L,Vago L,Older Aguilar AM,Gleimer M,Hammond JA,Guethlein LA,Bushnell DA,Robinson PJ,Parham P

11-9983 was used in Flow cytometry/Cell sorting to reinvestigate the HLA class I specificity of human killer cell immunoglobulin-like receptor 2DS4 (KIR2DS4) and its functional implications.

Mon Oct 26 00:00:00 EDT 2009

Physical and functional interaction of transmembrane thioredoxin-related protein with major histocompatibility complex class I heavy chain: redox-based protein quality control and its potential relevance to immune responses.

Molecular biology of the cell

Matsuo Y,Masutani H,Son A,Kizaka-Kondoh S,Yodoi J

11-9983 was used in Flow cytometry/Cell sorting to suggest a specific role for TMX and its mechanism of action in redox-based ER quality control in relation to MHC class I.

Sun Nov 01 00:00:00 EDT 2009

Mamu-A01/K(b) transgenic and MHC Class I knockout mice as a tool for HIV vaccine development.

Virology

Li J,Srivastava T,Rawal R,Manuel E,Isbell D,Tsark W,La Rosa C,Wang Z,Li Z,Barry PA,Hagen KD,Longmate J,Diamond DJ

11-9983 was used in Flow cytometry/Cell sorting to develop the Mamu-A01/K(b) Tg mice, which provide a model system to study the Mamu-A01 restricted T-cell response.

Sat Apr 25 00:00:00 EDT 2009

Mamu-A01/K(b) transgenic and MHC Class I knockout mice as a tool for HIV vaccine development.

Virology

Li J,Srivastava T,Rawal R,Manuel E,Isbell D,Tsark W,La Rosa C,Wang Z,Li Z,Barry PA,Hagen KD,Longmate J,Diamond DJ

11-9983 was used in Flow cytometry/Cell sorting to develop the Mamu-A01/K(b) Tg mice, which provide a model system to study the Mamu-A01 restricted T-cell response.

Sat Apr 25 00:00:00 EDT 2009

Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I.

Nature immunology

Di Pucchio T,Chatterjee B,Smed-Sörensen A,Clayton S,Palazzo A,Montes M,Xue Y,Mellman I,Banchereau J,Connolly JE

11-9983 was used in Flow cytometry/Cell sorting to demonstrate that pDCs use 'ready made' stores of MHC class I to rapidly present exogenous antigen to CD8+ T cells.

Thu May 01 00:00:00 EDT 2008

Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I.

Nature immunology

Di Pucchio T,Chatterjee B,Smed-Sörensen A,Clayton S,Palazzo A,Montes M,Xue Y,Mellman I,Banchereau J,Connolly JE

11-9983 was used in Flow cytometry/Cell sorting to demonstrate that pDCs use 'ready made' stores of MHC class I to rapidly present exogenous antigen to CD8+ T cells.

Thu May 01 00:00:00 EDT 2008

Polymorphic sites away from the Bw4 epitope that affect interaction of Bw4+ HLA-B with KIR3DL1.

Journal of immunology (Baltimore, Md. : 1950)

Sanjanwala B,Draghi M,Norman PJ,Guethlein LA,Parham P

11-9983 was used in Flow cytometry/Cell sorting to characterise the polymorphic sites throughout the HLA class I molecule that influence the interaction of the Bw4 epitope with KIR3DL1.

Sat Nov 01 00:00:00 EDT 2008

Clinical significance of costimulatory molecules CD80/CD86 expression in IgA nephropathy.

Kidney international

Wu Q,Jinde K,Endoh M,Sakai H

11-9983 was used in Flow cytometry/Cell sorting to suggest that CD80 and CD86 activate T cells in IgAN, CD80/CD86 expressions correlated with renal function at the time of renal biopsy, and monocyte/macrophages and tubular epithelial cells act as APC.

Mon Mar 01 00:00:00 EST 2004

High level of aneuploidy of chromosome 6 by FISH analysis of head and neck squamous cell carcinoma: limited applicability of LOH analysis to define HLA loss.

Human immunology

Koene GJ,Arts-Hilkes YH,van Dijk AJ,van der Ven KJ,Slootweg PJ,de Weger RA,Tilanus MG

Wed Dec 01 00:00:00 EST 2004

A study of human leukocyte antigen G expression in hydatidiform moles.

American journal of obstetrics and gynecology

Goldman-Wohl D,Ariel I,Greenfield C,Hochner-Celnikier D,Lavy Y,Yagel S

Wed Aug 01 00:00:00 EDT 2001

Bioinformatics

Protein Aliases: A29 protein; alpha chain of MHC class II; antigen presenting molecule; class I MHC, HLA-B antigen; epididymis secretory protein Li 83; H-2K; H-2K(d); H2-K; histocompatibility antigen; HLA -B; HLA A; HLA B-40011; HLA B44; HLA C; HLA class I antigen; HLA class I antigen HLA-B; HLA class I histocompatibility antigen C alpha chain; HLA class I histocompatibility antigen Cw-1 alpha chain; HLA class I histocompatibility antigen, A alpha chain; HLA class I histocompatibility antigen, A-30 alpha chain; HLA class I histocompatibility antigen, A-33 alpha chain; HLA class I histocompatibility antigen, A-74 alpha chain; HLA class I histocompatibility antigen, B alpha chain; HLA class I histocompatibility antigen, B-47 alpha chain; HLA class I histocompatibility antigen, B-50 alpha chain; HLA class I histocompatibility antigen, B-82 alpha chain; HLA class I histocompatibility antigen, C alpha chain; HLA class I histocompatibility antigen, Cw-15 alpha chain; HLA class I histocompatibility antigen, Cw-18 alpha chain; HLA locus; HLA molecule; HLA-A; HLA-A locus alpha 2 domain; HLA-A null; HLA-Aw33.1; HLA-B; HLA-B 1502; HLA-B alpha chain; HLA-B alpha chain (B*2706); HLA-B alpha chain (B*5002); HLA-B alpha-chain; HLA-B35; HLA-B35 antigen; HLA-Bw50 antigen; HLA-C; HLA-C alpha chain; HLA-C alpha chain (HLA-Cw*15v); HLA-C alpha chain for Cw*18GB; HLA-C alpha-chain; HLA-C antigen; HLA-Cw; HLA-Cw*04GB; HLA-Cw*1702; HLA-Cw*18GB; HLA-Cw-1503; Human leukocyte antigen A; Human leukocyte antigen B; Human leukocyte antigen C; human leukocyte antigen-C alpha chain; hypothetical protein; lecocyte antigen B; leucocyte antigen A; Leukocyte Antigen; leukocyte antigen C; leukocyte antigen class I-A; leukocyte antigen class I-B; Leukoocyte Antigen; lymphocyte antigen; major histocompatability complex B antigen; major histocompatibility antigen HLA-C; MCH class I antigen; MGC184092; MGC7052; MHC 1; MHC antigen; MHC clas I antigen; MHC Class 1; MHC class 1 antigen; MHC class I; MHC class I alpha chain; MHC class I anitgen; MHC class I anti; MHC Class I antigen; MHC class I antigen A*30; MHC class I antigen A*33; MHC class I antigen A*74; MHC class I antigen B*47; MHC class I antigen B*50; MHC class I antigen B*82; MHC class I antigen Cw*15; MHC class I antigen Cw*18; MHC class I antigen GN00104; MHC class I antigen heavy chain; MHC class I antigen heavy chain HLA-C; MHC class I antigen HLA-A heavy chain; MHC class I antigen HLA-A33; MHC class I antigen HLA-B alpha chain; MHC class I antigen HLA-B heavy chain; MHC class I antigen null protein; MHC class I antigen SHCHA; MHC class I antigene; MHC class I histocompatibility antigen; MHC class I human leukocyte antigen; MHC class I molecule; MHC class I protein; MHC class II antigen; MHC class l antigen; MHC classI antigen; MHC HLA-ABC; MHC HLA-B cell surface glycoprotein; MHC HLA-B transmembrane glycoprotein; MHC HLA-B27-HS; MHC HLA-B27d; MHC HLA-B39N; MHC I HLA; MHC1; surface antigen; truncated class I antigen; truncated MHC class I antigen

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Gene Aliases: AS; Aw-33; Aw-74; B-4901; B-5001; Bw-47; Bw-50; D6S204; HEL-S-83; HLA-A; HLA-A11; HLA-A33; HLA-B; HLA-B*45ZJ; HLA-B-3506; HLA-B-3905; HLA-B-5502; HLA-B-5602; HLA-B15; HLA-B39; HLA-B49; HLA-B50; HLA-B55; HLA-B59; HLA-B61; HLA-C; HLA-Cw; HLA-DQB1; HLA-DRB1; HLA-JY3; HLAA; HLAB; HLAC; HLC-C; MHC; PSORS1; SPDA1

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UniProt ID: (Human) Q9TQM6, (Human) Q31603, (Human) Q29990

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Entrez Gene ID: (Human) 3105, (Human) 3106, (Human) 3107

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Function(s)

protein binding beta-2-microglobulin binding peptide antigen binding poly(A) RNA binding antigen binding major histocompatibility complex protein

Process(es)

antigen processing and presentation of peptide antigen via MHC class I antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent viral process antigen processing and presentation regulation of immune response interferon-gamma-mediated signaling pathway type I interferon signaling pathway

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HLA-ABC Monoclonal Antibody (W6/32), FITC, eBioscience™

HLA-ABC Antibody (11-9983-42) in Flow

Product Details

11-9983-42

Immunohistochemistry (Frozen) (IHC (F))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Neutralization (Neu)

Species Reactivity

Published species

Host/Isotype

Recommended Isotype Control

Class

Type

Clone

Conjugate

Excitation/Emission Max

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

How to use the Panel Builder

Bioinformatics

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