Product References
Eosinophils protect against pulmonary hypertension through 14-HDHA and 17-HDHA.
The European respiratory journal
Shu T,Zhang J,Zhou Y,Chen Z,Li J,Tang Q,Lei W,Xing Y,Wang J,Wang C
12-1702-82 was used in Flow cytometry/Cell sorting to show that in PH development without external inflammatory stimulus, peripheral blood exhibits a low EOS level, in which EOS play a protective role through suppressing perivascular inflammation and maintaining PASMC homeostasis via 14/17-HDHA.
Wed Mar 01 00:00:00 EST 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
Published figure using CD170 (Siglec F) monoclonal antibody (Product # 12-1702-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
Calcaratarin D, a labdane diterpenoid, attenuates mouse asthma via modulating alveolar macrophage function.
British journal of pharmacology
Liao W,Foo HYC,Tran TNQ,Chai CLL,Wong WSF
12-1702-82 was used in Flow cytometry/Cell sorting to demonstrate for the first time that CalD is a novel anti-inflammatory natural compound for allergic asthma that modulates AM function.
Sat Apr 01 00:00:00 EDT 2023
Group 2 innate lymphoid cells protect mouse heart from myocardial infarction injury via interleukin 5, eosinophils, and dendritic cells.
Cardiovascular research
Liu T,Meng Z,Liu J,Li J,Zhang Y,Deng Z,Luo S,Wang M,Huang Q,Zhang S,Fendt P,Devouassoux J,Li D,McKenzie ANJ,Nahrendorf M,Libby P,Guo J,Shi GP
12-1702-82 was used in Flow cytometry/Cell sorting to reveal an indirect cardiac reparative role of ILC2 in post-MI hearts via the IL5, EOS, and DC mechanism.
Tue May 02 00:00:00 EDT 2023
Cells of the human intestinal tract mapped across space and time.
Nature
Elmentaite R,Kumasaka N,Roberts K,Fleming A,Dann E,King HW,Kleshchevnikov V,Dabrowska M,Pritchard S,Bolt L,Vieira SF,Mamanova L,Huang N,Perrone F,Goh Kai'En I,Lisgo SN,Katan M,Leonard S,Oliver TRW,Hook CE,Nayak K,Campos LS,Domínguez Conde C,Stephenson E,Engelbert J,Botting RA,Polanski K,van Dongen S,Patel M,Morgan MD,Marioni JC,Bayraktar OA,Meyer KB,He X,Barker RA,Uhlig HH,Mahbubani KT,Saeb-Parsy K,Zilbauer M,Clatworthy MR,Haniffa M,James KR,Teichmann SA
Published figure using CD170 (Siglec F) monoclonal antibody (Product # 12-1702-82) in Flow Cytometry
Wed Sep 01 00:00:00 EDT 2021
Arf6 exacerbates allergic asthma through cell-to-cell transmission of ASC inflammasomes.
JCI insight
Lee S,Ishitsuka A,Kuroki T,Lin YH,Shibuya A,Hongu T,Funakoshi Y,Kanaho Y,Nagata K,Kawaguchi A
Published figure using CD170 (Siglec F) monoclonal antibody (Product # 12-1702-82) in Flow Cytometry
Mon Aug 23 00:00:00 EDT 2021
Nociceptor neurons promote IgE class switch in B cells.
JCI insight
Mathur S,Wang JC,Seehus CR,Poirier F,Crosson T,Hsieh YC,Doyle B,Lee S,Woolf CJ,Foster SL,Talbot S
12-1702-82 was used in Flow cytometry/Cell sorting to suggest that nociceptors, in addition to their contributions to innate immunity, play a key role in modulating the adaptive immune response, particularly B cell antibody class switching to IgE.
Wed Dec 22 00:00:00 EST 2021
Muc5ac Expression Protects the Colonic Barrier in Experimental Colitis.
Inflammatory bowel diseases
Olli KE,Rapp C,O'Connell L,Collins CB,McNamee EN,Jensen O,Jedlicka P,Allison KC,Goldberg MS,Gerich ME,Frank DN,Ir D,Robertson CE,Evans CM,Aherne CM
12-1702 was used in Flow cytometry/Cell sorting to test the expression and functional role of MUC5AC/Muc5ac in UC biopsies and murine colitis.
Thu Aug 20 00:00:00 EDT 2020
Evaluation of K18-hACE2 Mice as a Model of SARS-CoV-2 Infection.
The American journal of tropical medicine and hygiene
Moreau GB,Burgess SL,Sturek JM,Donlan AN,Petri WA,Mann BJ
Published figure using CD170 (Siglec F) monoclonal antibody (Product # 12-1702-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2020
Eosinophils improve cardiac function after myocardial infarction.
Nature communications
Liu J,Yang C,Liu T,Deng Z,Fang W,Zhang X,Li J,Huang Q,Liu C,Wang Y,Yang D,Sukhova GK,Lindholt JS,Diederichsen A,Rasmussen LM,Li D,Newton G,Luscinskas FW,Liu L,Libby P,Wang J,Guo J,Shi GP
Published figure using CD170 (Siglec F) monoclonal antibody (Product # 12-1702-82) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
The cis-Regulatory Atlas of the Mouse Immune System.
Cell
Yoshida H,Lareau CA,Ramirez RN,Rose SA,Maier B,Wroblewska A,Desland F,Chudnovskiy A,Mortha A,Dominguez C,Tellier J,Kim E,Dwyer D,Shinton S,Nabekura T,Qi Y,Yu B,Robinette M,Kim KW,Wagers A,Rhoads A,Nutt SL,Brown BD,Mostafavi S,Buenrostro JD,Benoist C
12-1702-82 was used in Flow Cytometry to generate matched epigenome and transcriptome measurements in 86 primary cell types that span the mouse immune system and its differentiation cascade.
Thu Feb 07 00:00:00 EST 2019
11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.
Journal of autoimmunity
Hardy RS,Fenton C,Croft AP,Naylor AJ,Begum R,Desanti G,Buckley CD,Lavery G,Cooper MS,Raza K
Published figure using CD170 (Siglec F) monoclonal antibody (Product # 12-1702-82) in Flow Cytometry
Wed Aug 01 00:00:00 EDT 2018
Non-redundant Functions of IL-6 Produced by Macrophages and Dendritic Cells in Allergic Airway Inflammation.
Frontiers in immunology
Gubernatorova EO,Gorshkova EA,Namakanova OA,Zvartsev RV,Hidalgo J,Drutskaya MS,Tumanov AV,Nedospasov SA
12-1702 was used in Flow cytometry/Cell sorting to indicate that IL-6 plays a pathogenic role in the HDM-induced asthma model and that lung macrophages and dendritic cells are the predominant sources of pathogenic IL-6 but contribute differently to the disease.
Wed Oct 02 00:00:00 EDT 2019
Der f 31, a novel allergen from Dermatophagoides farinae, activates epithelial cells and enhances lung-resident group 2 innate lymphoid cells.
Scientific reports
Wang H,Lin J,Zeng L,Ouyang C,Ran P,Yang P,Liu Z
Published figure using CD170 (Siglec F) monoclonal antibody (Product # 12-1702-82) in Flow Cytometry
Thu Aug 17 00:00:00 EDT 2017
Expression of the inhibitory Ly49E receptor is not critically involved in the immune response against cutaneous, pulmonary or liver tumours.
Scientific reports
Filtjens J,Keirsse J,Van Ammel E,Taveirne S,Van Acker A,Kerre T,Taghon T,Vandekerckhove B,Plum J,Van Ginderachter JA,Leclercq G
12-1702 was used in Flow cytometry/Cell sorting to study the involvement of the inhibitory Ly49E NK cell receptor and its activating molecule uPA in skin, lung, and liver tumorigenesis.
Fri Jul 29 00:00:00 EDT 2016
Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production.
The Journal of allergy and clinical immunology
Doherty TA,Khorram N,Lund S,Mehta AK,Croft M,Broide DH
12-1702 was used in Flow cytometry/Cell sorting to determine if leukotrienes contribute to asthma pathogenesis by activating type 2 innate lymphoid cells and inducing interleukin production.
Mon Jul 01 00:00:00 EDT 2013