Product References
Chronic psychological stress promotes breast cancer pre-metastatic niche formation by mobilizing splenic MDSCs via TAM/CXCL1 signaling.
Journal of experimental & clinical cancer research : CR
Zheng Y,Wang N,Wang S,Zhang J,Yang B,Wang Z
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2069-42) in Flow Cytometry
Sat May 20 00:00:00 EDT 2023
Germline Neurofibromin 1 mutation enhances the anti-tumour immune response and decreases juvenile myelomonocytic leukaemia tumourigenicity.
British journal of haematology
Wang W,Li X,Qin X,Miao Y,Zhang Y,Li S,Yao R,Yang Y,Yu L,Zhu H,Song L,Mao S,Wang X,Chen J,Feng H,Li Y
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2069-42) in Flow Cytometry
Sat Jul 01 00:00:00 EDT 2023
Heme oxygenase-1 determines the cell fate of ferroptotic death of alveolar macrophages in COPD.
Frontiers in immunology
Li Y,Yang Y,Guo T,Weng C,Yang Y,Wang Z,Zhang L,Li W
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2069-42) in Flow Cytometry
Wed May 24 00:00:00 EDT 2023
Heme oxygenase-1 determines the cell fate of ferroptotic death of alveolar macrophages in COPD.
Frontiers in immunology
Li Y,Yang Y,Guo T,Weng C,Yang Y,Wang Z,Zhang L,Li W
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2069-42) in Flow Cytometry
Wed May 24 00:00:00 EDT 2023
miR‑382 inhibits breast cancer progression and metastasis by affecting the M2 polarization of tumor‑associated macrophages by targeting PGC‑1α.
International journal of oncology
Zhou H,Gan M,Jin X,Dai M,Wang Y,Lei Y,Lin Z,Ming J
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2069-42) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2022
Sphingomyelin synthase 2 is a positive regulator of the CSF1R-STAT3 pathway in pancreatic cancer-associated macrophage.
Frontiers in pharmacology
He S,Gu X,Yang J,Xu F,Hu J,Wang W,Huang Y,Lou B,Ding T,Zhou L,Ye D,Yu K,Dong J
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2069-42) in Flow Cytometry
Fri Nov 04 00:00:00 EDT 2022
M2-like tumor-associated macrophages transmit exosomal miR-27b-3p and maintain glioblastoma stem-like cell properties.
Cell death discovery
Zhao G,Ding L,Yu H,Wang W,Wang H,Hu Y,Qin L,Deng G,Xie B,Li G,Qi L
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2069-42) in Flow Cytometry
Thu Aug 04 00:00:00 EDT 2022
Genipin Attenuates Diabetic Cognitive Impairment by Reducing Lipid Accumulation and Promoting Mitochondrial Fusion via FABP4/Mfn1 Signaling in Microglia.
Antioxidants (Basel, Switzerland)
Liu W,Li K,Zheng M,He L,Chen T
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2069-42) in Flow Cytometry
Thu Dec 29 00:00:00 EST 2022
Genipin Attenuates Diabetic Cognitive Impairment by Reducing Lipid Accumulation and Promoting Mitochondrial Fusion via FABP4/Mfn1 Signaling in Microglia.
Antioxidants (Basel, Switzerland)
Liu W,Li K,Zheng M,He L,Chen T
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2069-42) in Flow Cytometry
Thu Dec 29 00:00:00 EST 2022
Ferroptosis Inducer Improves the Efficacy of Oncolytic Virus-Mediated Cancer Immunotherapy.
Biomedicines
Liu W,Chen H,Zhu Z,Liu Z,Ma C,Lee YJ,Bartlett DL,Guo ZS
12-2069-42 was used in Flow Cytometry to demonstrate that erastin can exert cytotoxicity on cancer cells via ferroptosis, but has little effect on immune activity by itself.
Wed Jun 15 00:00:00 EDT 2022
NIL10: A New IL10-Receptor Binding Nanoparticle That Induces Cardiac Protection in Mice and Pigs Subjected to Acute Myocardial Infarction through STAT3/NF-κB Activation.
Pharmaceutics
Tesoro L,Hernández I,Ramírez-Carracedo R,Díez-Mata J,Alcharani N,Jiménez-Guirado B,Ovejero-Paredes K,Filice M,Zamorano JL,Saura M,Zaragoza C,Botana L
12-2069-42 was used in flow cytometry to show that NIL10, a novel anti-inflammatory nanoparticle, induces cardiac protection after acute myocardial infarction following cardiac ischemia/reperfusion.
Mon Sep 26 00:00:00 EDT 2022
AIM2 inflammasome mediates hallmark neuropathological alterations and cognitive impairment in a mouse model of vascular dementia.
Molecular psychiatry
Poh L,Fann DY,Wong P,Lim HM,Foo SL,Kang SW,Rajeev V,Selvaraji S,Iyer VR,Parathy N,Khan MB,Hess DC,Jo DG,Drummond GR,Sobey CG,Lai MKP,Chen CL,Lim LHK,Arumugam TV
12-2069-42 was used in Immunohistochemistry to investigate its effect on the innate immune response-particularly the inflammasome signaling pathway using a bilateral common carotid artery stenosis (BCAS) mouse model of vascular dementia (VaD).
Sun Aug 01 00:00:00 EDT 2021
Interleukin 6 regulates the expression of programmed cell death ligand 1 in thyroid cancer.
Cancer science
Zhang GQ,Jiao Q,Shen CT,Song HJ,Zhang HZ,Qiu ZL,Luo QY
12-2069 was used in Flow cytometry/Cell sorting to investigate the expression of IL-6 and PD-L1 in thyroid cancer, and whether IL-6 regulates the PD-L1 expression.
Mon Mar 01 00:00:00 EST 2021
Interleukin 6 regulates the expression of programmed cell death ligand 1 in thyroid cancer.
Cancer science
Zhang GQ,Jiao Q,Shen CT,Song HJ,Zhang HZ,Qiu ZL,Luo QY
12-2069 was used in Flow cytometry/Cell sorting to investigate the expression of IL-6 and PD-L1 in thyroid cancer, and whether IL-6 regulates the PD-L1 expression.
Mon Mar 01 00:00:00 EST 2021
miR-155-5p regulates macrophage M1 polarization and apoptosis in the synovial fluid of patients with knee osteoarthritis.
Experimental and therapeutic medicine
Li GS,Cui L,Wang GD
12-2069 was used in Flow cytometry/Cell sorting to suggest that miR-155-5p may serve as a potential therapeutic target for KOA.
Fri Jan 01 00:00:00 EST 2021
The role of irreversible electroporation in promoting M1 macrophage polarization via regulating the HMGB1-RAGE-MAPK axis in pancreatic cancer.
Oncoimmunology
He C,Sun S,Zhang Y,Xie F,Li S
12-2069-42 was used in Flow Cytometry to analyze the associated markers of macrophages after exposure to tumor culture supernatant (TSN) of tumor cells treated with electroporation.
Thu Mar 11 00:00:00 EST 2021
The role of irreversible electroporation in promoting M1 macrophage polarization via regulating the HMGB1-RAGE-MAPK axis in pancreatic cancer.
Oncoimmunology
He C,Sun S,Zhang Y,Xie F,Li S
12-2069-42 was used in Flow Cytometry to analyze the associated markers of macrophages after exposure to tumor culture supernatant (TSN) of tumor cells treated with electroporation.
Thu Mar 11 00:00:00 EST 2021
Paliperidone Inhibits Glioblastoma Growth in Mouse Brain Tumor Model and Reduces PD-L1 Expression.
Cancers
Liu YS,Huang BR,Lin CJ,Shen CK,Lai SW,Chen CW,Lin HJ,Lin CH,Hsieh YC,Lu DY
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2069-42) in Flow Cytometry
Sat Aug 28 00:00:00 EDT 2021
High-Molecular-Weight Hyaluronic Acid Inhibits IL-1β-Induced Synovial Inflammation and Macrophage Polarization through the GRP78-NF-κB Signaling Pathway.
International journal of molecular sciences
Lee CH,Chiang CF,Kuo FC,Su SC,Huang CL,Liu JS,Lu CH,Hsieh CH,Wang CC,Lee CH,Shen PH
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2069-42) in Flow Cytometry
Wed Nov 03 00:00:00 EDT 2021
Annexin A1 drives macrophage skewing to accelerate muscle regeneration through AMPK activation.
The Journal of clinical investigation
McArthur S,Juban G,Gobbetti T,Desgeorges T,Theret M,Gondin J,Toller-Kawahisa JE,Reutelingsperger CP,Chazaud B,Perretti M,Mounier R
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2069-42) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
Lung transplantation for patients with severe COVID-19.
Science translational medicine
Bharat A,Querrey M,Markov NS,Kim S,Kurihara C,Garza-Castillon R,Manerikar A,Shilatifard A,Tomic R,Politanska Y,Abdala-Valencia H,Yeldandi AV,Lomasney JW,Misharin AV,Budinger GRS
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2069-42) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Lung transplantation for patients with severe COVID-19.
Science translational medicine
Bharat A,Querrey M,Markov NS,Kim S,Kurihara C,Garza-Castillon R,Manerikar A,Shilatifard A,Tomic R,Politanska Y,Abdala-Valencia H,Yeldandi AV,Lomasney JW,Misharin AV,Budinger GRS
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2069-42) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
The Immunosuppressive Microenvironment in BRCA1-IRIS-Overexpressing TNBC Tumors Is Induced by Bidirectional Interaction with Tumor-Associated Macrophages.
Cancer research
Sami E,Paul BT,Koziol JA,ElShamy WM
12-2069 was used in Flow cytometry/Cell sorting to investigate the effects of BRCA1-IRIS over-expression on macrophage recruitment and the production of protumour M2 TAMs.
Sun Mar 01 00:00:00 EST 2020
In Situ Therapeutic Cancer Vaccination with an Oncolytic Virus Expressing Membrane-Tethered IL-2.
Molecular therapy oncolytics
Liu W,Dai E,Liu Z,Ma C,Guo ZS,Bartlett DL
12-2069 was used in Flow cytometry/Cell sorting to establish in situ anticancer immunotherapy regimens.
Fri Jun 26 00:00:00 EDT 2020
CAIX Regulates GBM Motility and TAM Adhesion and Polarization through EGFR/STAT3 under Hypoxic Conditions.
International journal of molecular sciences
Huang BR,Liu YS,Lai SW,Lin HJ,Shen CK,Yang LY,Lu DY
12-2069 was used in Flow cytometry/Cell sorting to provide a comprehensive understanding of the mechanisms of CAIX in the GBM microenvironment.
Fri Aug 14 00:00:00 EDT 2020
CAIX Regulates GBM Motility and TAM Adhesion and Polarization through EGFR/STAT3 under Hypoxic Conditions.
International journal of molecular sciences
Huang BR,Liu YS,Lai SW,Lin HJ,Shen CK,Yang LY,Lu DY
12-2069 was used in Flow cytometry/Cell sorting to provide a comprehensive understanding of the mechanisms of CAIX in the GBM microenvironment.
Fri Aug 14 00:00:00 EDT 2020
Nanotopographical Coatings Induce an Early Phenotype-Specific Response of Primary Material-Resident M1 and M2 Macrophages.
Materials (Basel, Switzerland)
Schmitz T,Jannasch M,Weigel T,Moseke C,Gbureck U,Groll J,Walles H,Hansmann J
12-2069-42 was used in Flow Cytometry to investigate the influence of tubular TiO2 and fractal TiN nanostructures on primary human macrophages with M1 or M2-phenotype.
Wed Mar 04 00:00:00 EST 2020
Nanotopographical Coatings Induce an Early Phenotype-Specific Response of Primary Material-Resident M1 and M2 Macrophages.
Materials (Basel, Switzerland)
Schmitz T,Jannasch M,Weigel T,Moseke C,Gbureck U,Groll J,Walles H,Hansmann J
12-2069-42 was used in Flow Cytometry to investigate the influence of tubular TiO2 and fractal TiN nanostructures on primary human macrophages with M1 or M2-phenotype.
Wed Mar 04 00:00:00 EST 2020
Tumor-associated macrophages promote human hepatoma Huh-7 cell migration and invasion through the Gli2/IGF-II/ERK1/2 axis by secreting TGF-β1.
Cancer biology & therapy
Liu M,Zhong YB,Shao J,Zhang C,Shi C
12-2069-42 was used in Flow cytometry/Cell sorting to conclude that the TGF-β1 secreted by TAMs promotes the migration, invasion and EMT of human hepatoma Huh-7 cells through the Gli2/IGF-II/ERK1/2 pathway.
Sun Nov 01 00:00:00 EDT 2020
A Subset of Skin Macrophages Contributes to the Surveillance and Regeneration of Local Nerves.
Immunity
Kolter J,Feuerstein R,Zeis P,Hagemeyer N,Paterson N,d'Errico P,Baasch S,Amann L,Masuda T,Lösslein A,Gharun K,Meyer-Luehmann M,Waskow C,Franzke CW,Grün D,Lämmermann T,Prinz M,Henneke P
12-2069 was used in Immunohistochemistry to delineate the postnatal development of dermal macrophages and their differentiation into subsets by adapting single-cell transcriptomics, fate mapping, and imaging.
Tue Jun 18 00:00:00 EDT 2019
Role of adipokine zinc-α2-glycoprotein in coronary heart disease.
American journal of physiology. Endocrinology and metabolism
Huang D,Mao X,Peng J,Cheng M,Bai T,Du M,Huang K,Liu B,Yang L,Huang K,Zhang F
12-2069 was used in Flow cytometry/Cell sorting to investigate the role of AZGP1 in atherosclerosis and CHD.
Sun Dec 01 00:00:00 EST 2019
An altered response in macrophage phenotype following damage in aged human skeletal muscle: implications for skeletal muscle repair.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Sorensen JR,Kaluhiokalani JP,Hafen PS,Deyhle MR,Parcell AC,Hyldahl RD
12-2069 was used in Flow cytometry/Cell sorting to test the hypothesis that macrophage polarisation is altered in old compared to young skeletal muscle, possibly contributing to the poor satellite cell response observed in older muscle tissue.
Sun Sep 01 00:00:00 EDT 2019
Astragalus polysaccharides (PG2) Enhances the M1 Polarization of Macrophages, Functional Maturation of Dendritic Cells, and T Cell-Mediated Anticancer Immune Responses in Patients with Lung Cancer.
Nutrients
Bamodu OA,Kuo KT,Wang CH,Huang WC,Wu ATH,Tsai JT,Lee KY,Yeh CT,Wang LS
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2069-42) in Flow Cytometry
Fri Sep 20 00:00:00 EDT 2019
Human lactoferrin attenuates the proinflammatory response of neonatal monocyte-derived macrophages.
Clinical and experimental immunology
Wisgrill L,Wessely I,Spittler A,Förster-Waldl E,Berger A,Sadeghi K
12-2069 was used in Flow cytometry/Cell sorting to investigate the immunomodulatory effects of human lactoferrin on differentiation and activation of monocyte-derived macrophages.
Fri Jun 01 00:00:00 EDT 2018
Inhibition of lncRNA NEAT1 suppresses the inflammatory response in IBD by modulating the intestinal epithelial barrier and by exosome-mediated polarization of macrophages.
International journal of molecular medicine
Liu R,Tang A,Wang X,Chen X,Zhao L,Xiao Z,Shen S
12-2069 was used in Flow cytometry/Cell sorting to show nuclear paraspeckle assembly transcript 1 expression is high in inflammatory bowel disease and is involved in the inflammatory response by regulating the intestinal epithelial barrier and exosome-mediated macrophage polarization.
Thu Nov 01 00:00:00 EDT 2018
Ginsenoside Rg3 Mitigates Atherosclerosis Progression in Diabetic apoE-/- Mice by Skewing Macrophages to the M2 Phenotype.
Frontiers in pharmacology
Guo M,Xiao J,Sheng X,Zhang X,Tie Y,Wang L,Zhao L,Ji X
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2069-42) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Similarities and differences between helminth parasites and cancer cell lines in shaping human monocytes: Insights into parallel mechanisms of immune evasion.
PLoS neglected tropical diseases
Narasimhan PB,Akabas L,Tariq S,Huda N,Bennuru S,Sabzevari H,Hofmeister R,Nutman TB,Tolouei Semnani R
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2069-42) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
Diabetes impairs wound healing by Dnmt1-dependent dysregulation of hematopoietic stem cells differentiation towards macrophages.
Nature communications
Yan J,Tie G,Wang S,Tutto A,DeMarco N,Khair L,Fazzio TG,Messina LM
12-2069 was used in Flow cytometry/Cell sorting to demonstrate for the first time that type 2 diabetes mellitus induces an haematopoietic stem cell-autonomous mechanism that causes impaired wound healing.
Tue Jan 02 00:00:00 EST 2018
In vitro chemotaxis and tissue remodeling assays quantitatively characterize foreign body reaction.
ALTEX
Jannasch M,Weigel T,Engelhardt L,Wiezoreck J,Gaetzner S,Walles H,Schmitz T,Hansmann J
12-2069 was used in Flow cytometry/Cell sorting to investigate the material dependency of fibroblast chemotaxis and tissue remodelling mediated by material-resident macrophages.
Tue Oct 10 00:00:00 EDT 2017
Metformin-treated cancer cells modulate macrophage polarization through AMPK-NF-κB signaling.
Oncotarget
Chiang CF,Chao TT,Su YF,Hsu CC,Chien CY,Chiu KC,Shiah SG,Lee CH,Liu SY,Shieh YS
12-2069 was used in Flow cytometry/Cell sorting to elucidate the anti-tumour mechanisms of metformin on macrophages.
Tue Mar 28 00:00:00 EDT 2017
Metformin-treated cancer cells modulate macrophage polarization through AMPK-NF-κB signaling.
Oncotarget
Chiang CF,Chao TT,Su YF,Hsu CC,Chien CY,Chiu KC,Shiah SG,Lee CH,Liu SY,Shieh YS
12-2069 was used in Flow cytometry/Cell sorting to elucidate the anti-tumour mechanisms of metformin on macrophages.
Tue Mar 28 00:00:00 EDT 2017
ALX receptor ligands define a biochemical endotype for severe asthma.
JCI insight
Ricklefs I,Barkas I,Duvall MG,Cernadas M,Grossman NL,Israel E,Bleecker ER,Castro M,Erzurum SC,Fahy JV,Gaston BM,Denlinger LC,Mauger DT,Wenzel SE,Comhair SA,Coverstone AM,Fajt ML,Hastie AT,Johansson MW,Peters MC,Phillips BR,Levy BD
12-2069 was used in Flow cytometry/Cell sorting to determine the role of ALX expression and ligands in severe asthma.
Thu Jul 20 00:00:00 EDT 2017
A comparative multi-parametric in vitro model identifies the power of test conditions to predict the fibrotic tendency of a biomaterial.
Scientific reports
Jannasch M,Gaetzner S,Weigel T,Walles H,Schmitz T,Hansmann J
12-2069 was used in Flow cytometry/Cell sorting to show that biomaterial ranking obtained under native plasma test conditions showed a high predictive accuracy compared to in vivo assessments.
Wed May 10 00:00:00 EDT 2017
The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9.
Nature immunology
Beatson R,Tajadura-Ortega V,Achkova D,Picco G,Tsourouktsoglou TD,Klausing S,Hillier M,Maher J,Noll T,Crocker PR,Taylor-Papadimitriou J,Burchell JM
12206942 was used in flow cytometry to investigate the impact of a cancer-specific MUC1 glycoform
Tue Nov 01 00:00:00 EDT 2016
A Systematic Study of the Effect of Different Molecular Weights of Hyaluronic Acid on Mesenchymal Stromal Cell-Mediated Immunomodulation.
PloS one
Gómez-Aristizábal A,Kim KP,Viswanathan S
12-2069 was used in Flow cytometry/Cell sorting to investigate the combined mechanism of action of MSCs and hyaluronic acid.
Wed Jul 06 00:00:00 EDT 2016
miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program.
Nature communications
Su S,Zhao Q,He C,Huang D,Liu J,Chen F,Chen J,Liao JY,Cui X,Zeng Y,Yao H,Su F,Liu Q,Jiang S,Song E
Mon Oct 05 00:00:00 EDT 2015
Doxycycline inhibits polarization of macrophages to the proangiogenic M2-type and subsequent neovascularization.
The Journal of biological chemistry
He L,Marneros AG
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2069-42) in Flow Cytometry
Fri Mar 21 00:00:00 EDT 2014
Doxycycline inhibits polarization of macrophages to the proangiogenic M2-type and subsequent neovascularization.
The Journal of biological chemistry
He L,Marneros AG
Published figure using CD206 (MMR) monoclonal antibody (Product # 12-2069-42) in Flow Cytometry
Fri Mar 21 00:00:00 EDT 2014
