Invitrogen

IL-17A Monoclonal Antibody (eBio64DEC17), Biotin, eBioscience™

IL-17A Antibody in Immunocytochemistry, Immunohistochemistry (ICC/IF, IHC)

FIGURE: 1 / 44

IL-17A Antibody (13-7179-81) in ICC/IF, IHC

International journal of molecular medicine 2016 - Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Immunocytochemistry and Immunohistochemistry

IL-17A Antibody in Immunocytochemistry, Radioimmune assays (ICC/IF, RIA)

IL-17A Antibody in Immunocytochemistry (ICC/IF)

IL-17A Antibody in Immunohistochemistry (IHC)

IL-17A Antibody in Flow Cytometry (Flow)

Product Image Gallery

Product Details

13-7179-81

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

Assay-Dependent

Immunocytochemistry (ICC/IF)

View 3 publications 3 publications

Flow Cytometry (Flow)

View 21 publications 21 publications

ELISA (ELISA)

0.5-2 µg/mL

View 7 publications 7 publications

Neutralization (Neu)

View 1 publication 1 publication

Radioimmune Assays (RIA)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Hamster, Human

Host/Isotype

Mouse / IgG1, kappa

Recommended Isotype Control

Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Biotin, eBioscience™

Class

Monoclonal

Type

Antibody

Clone

eBio64DEC17

Conjugate

Biotin Biotin Biotin

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

0.09% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_494044

Product Specific Information

Description: The eBio64DEC17 antibody reacts with human IL-17A. The eBio64DEC17 antibody is a neutralizing antibody. Interleukin-17A (IL-17A) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection. The cDNA encoding human IL-17A was isolated from a library of CD4+ T cells; the encoded protein exhibits 72 percent amino acid identity with HVS13 , an open reading frame from a T lymphotropic Herpesvirus saimiri, and 63 percent with mouse CTLA-8 (cytotoxic T-lymphocyte associated antigen-8). Human IL-17A exists as glycosylated 20-30 kD homodimers. High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells. IL-17A enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts. Human IL-17A also stimulates epithelial, endothelial, or fibroblastic cells to secrete IL-6, IL-8, G-CSF, and PGE2. In the presence of human IL-17A, fibroblasts can sustain the proliferation of CD34+ hematopoietic progenitors and induce maturation into neutrophils. Mouse, rat, and human IL-17A can induce IL-6 secretion in mouse stromal cells, indicating that all homologs can recognize the mouse IL-17A receptor.

IL-23-dependent, IL-17A-producing CD4+ T cells (Th-17 cells) have been identified as a unique subset of Th cells that develops along a pathway that is distinct from the Th1- and Th2- cell differentiation pathways. The hallmark effector molecules of Th1 and Th2 cells, e.g., IFN gamma and IL-4, have each been found to negatively regulate the generation of these Th-17 cells.

Intracellular staining by eBio64DEC17 antibody identifies the same cell population as the eBio64CAP17 antibody, as can be seen in co-staining experiments using both antibodies.

Applications Reported: The eBio64DEC17 antibody has been reported for use as the detection antibody in human IL-17A ELISA and ELISPOT assays.

Applications Tested: The biotinylated eBio64DEC17 antibody has been tested as the detection antibody in a sandwich ELISA for measurement of human IL-17A protein levels, in combination with the Affinity Purified eBio64CAP17 antibody (14-7178) for capture and recombinant human IL-17A (14-8179) as the standard. A suitable range of concentrations of this antibody for ELISA detection is 0.5 - 2.0 µg/mL. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 1000 pg/mL - 8 pg/mL should be included in each ELISA plate.

Filtration: 0.2 µm post-manufacturing filtered.

Target Information

Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection. IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217). High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts. In particular, human IL-17A also stimulates epithelial, endothelial, or fibroblastic cells to secrete IL-6, IL-8, G-CSF, and PGE2. In the presence of human IL-17A, fibroblasts can sustain the proliferation of CD34+ hematopoietic progenitors and induce maturation into neutrophils. Mouse, rat, and human IL-17A can induce IL-6 secretion in mouse stromal cells, indicating that all homologs can recognize the mouse receptor. IL-17A regulates the activities of NF-kappa B and mitogen-activated protein kinases, stimulates the expression of IL-6 and cyclooxygenase-2 (PTGS2/COX-2), and enhances the production of nitric oxide (NO).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Identification of aryl hydrocarbon receptor as a barrier to HIV-1 infection and outgrowth in CD4⁺ T cells.

Cell reports

Chatterjee D,Zhang Y,Ngassaki-Yoka CD,Dutilleul A,Khalfi S,Hernalsteens O,Wiche Salinas TR,Dias J,Chen H,Smail Y,Goulet JP,Bell B,Routy JP,Van Lint C,Ancuta P

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Tue Jun 27 00:00:00 EDT 2023

Cathepsin S inhibition in dendritic cells prevents Th17 cell differentiation in perivascular adipose tissues following vascular injury in diabetic rats.

Journal of biochemical and molecular toxicology

Peng H,Lv Y,Li C,Cheng Z,He S,Wang C,Liu J

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Fri Sep 01 00:00:00 EDT 2023

FABP4 facilitates inflammasome activation to induce the Treg/Th17 imbalance in preeclampsia via forming a positive feedback with IL-17A.

Molecular therapy. Nucleic acids

Chang GP,Yang XL,Liu W,Lin S,Yang SL,Zhao MY

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Fri Jun 04 00:00:00 EDT 2021

Small molecule allosteric inhibitors of RORγt block Th17-dependent inflammation and associated gene expression in vivo.

PloS one

Saenz SA,Local A,Carr T,Shakya A,Koul S,Hu H,Chourb L,Stedman J,Malley J,D'Agostino LA,Shanmugasundaram V,Malona J,Schwartz CE,Beebe L,Clements M,Rajaraman G,Cho J,Jiang L,Dubrovskiy A,Kreilein M,Shimanovich R,Hamann LG,Escoubet L,Ellis JM

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Wed Dec 29 00:00:00 EST 2021

YY1 regulation by miR-124-3p promotes Th17 cell pathogenicity through interaction with T-bet in rheumatoid arthritis.

JCI insight

Lin J,Tang J,Lin J,He Y,Yu Z,Jiang R,Yang B,Ou Q

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Mon Nov 22 00:00:00 EST 2021

Neutrophil-Derived IL-17 Promotes Ventilator-Induced Lung Injury via p38 MAPK/MCP-1 Pathway Activation.

Frontiers in immunology

Liao X,Zhang W,Dai H,Jing R,Ye M,Ge W,Pei S,Pan L

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Immunohistochemistry (Paraffin)

Mon Feb 14 00:00:00 EST 2022

Th17/Treg imbalance modulates rat myocardial fibrosis and heart failure by regulating LOX expression.

Acta physiologica (Oxford, England)

Lu M,Qin X,Yao J,Yang Y,Zhao M,Sun L

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Neutralization

Sun Nov 01 00:00:00 EDT 2020

Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation.

Nature communications

Iske J,Seyda M,Heinbokel T,Maenosono R,Minami K,Nian Y,Quante M,Falk CS,Azuma H,Martin F,Passos JF,Niemann CU,Tchkonia T,Kirkland JL,Elkhal A,Tullius SG

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Thu Aug 27 00:00:00 EDT 2020

Developing Human Skin Contains Lymphocytes Demonstrating a Memory Signature.

Cell reports. Medicine

Dhariwala MO,Karthikeyan D,Vasquez KS,Farhat S,Weckel A,Taravati K,Leitner EG,Clancy S,Pauli M,Piper ML,Cohen JN,Ashouri JF,Lowe MM,Rosenblum MD,Scharschmidt TC

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Tue Nov 17 00:00:00 EST 2020

CXCL4 is a novel inducer of human Th17 cells and correlates with IL-17 and IL-22 in psoriatic arthritis.

European journal of immunology

Affandi AJ,Silva-Cardoso SC,Garcia S,Leijten EFA,van Kempen TS,Marut W,van Roon JAG,Radstake TRDJ

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Thu Mar 01 00:00:00 EST 2018

Accumulation of T-helper 22 cells, interleukin-22 and myeloid-derived suppressor cells promotes gastric cancer progression in elderly patients.

Oncology letters

Chen X,Wang Y,Wang J,Wen J,Jia X,Wang X,Zhang H

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Sun Jul 01 00:00:00 EDT 2018

Cutting Edge: Selective Oral ROCK2 Inhibitor Reduces Clinical Scores in Patients with Psoriasis Vulgaris and Normalizes Skin Pathology via Concurrent Regulation of IL-17 and IL-10.

Journal of immunology (Baltimore, Md. : 1950)

Zanin-Zhorov A,Weiss JM,Trzeciak A,Chen W,Zhang J,Nyuydzefe MS,Arencibia C,Polimera S,Schueller O,Fuentes-Duculan J,Bonifacio KM,Kunjravia N,Cueto I,Soung J,Fleischmann RM,Kivitz A,Lebwohl M,Nunez M,Woodson J,Smith SL,West RF,Berger M,Krueger JG,Ryan JL,Waksal SD

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in ELISA

Mon May 15 00:00:00 EDT 2017

Enhancing the toolbox to study IL-17A in cattle and sheep.

Veterinary research

Wattegedera SR,Corripio-Miyar Y,Pang Y,Frew D,McNeilly TN,Palarea-Albaladejo J,McInnes CJ,Hope JC,Glass EJ,Entrican G

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Sat Apr 08 00:00:00 EDT 2017

Berberine exerts an anti-inflammatory role in ocular Behcet's disease.

Molecular medicine reports

Yang Y,Wang Q,Xie M,Liu P,Qi X,Liu X,Li Z

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Sun Jan 01 00:00:00 EST 2017

Transcriptional signature of human pro-inflammatory T_H17 cells identifies reduced IL10 gene expression in multiple sclerosis.

Nature communications

Hu D,Notarbartolo S,Croonenborghs T,Patel B,Cialic R,Yang TH,Aschenbrenner D,Andersson KM,Gattorno M,Pham M,Kivisakk P,Pierre IV,Lee Y,Kiani K,Bokarewa M,Tjon E,Pochet N,Sallusto F,Kuchroo VK,Weiner HL

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Fri Nov 17 00:00:00 EST 2017

Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation.

JCI insight

Tischner D,Grimm M,Kaur H,Staudenraus D,Carvalho J,Looso M,Günther S,Wanke F,Moos S,Siller N,Breuer J,Schwab N,Zipp F,Waisman A,Kurschus FC,Offermanns S,Wettschureck N

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Thu Aug 03 00:00:00 EDT 2017

CD16⁺ Monocyte Subset Was Enriched and Functionally Exacerbated in Driving T-Cell Activation and B-Cell Response in Systemic Lupus Erythematosus.

Frontiers in immunology

Zhu H,Hu F,Sun X,Zhang X,Zhu L,Liu X,Li X,Xu L,Shi L,Gan Y,Su Y

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in ELISA

Wed Nov 20 00:00:00 EST 2019

CD16⁺ Monocyte Subset Was Enriched and Functionally Exacerbated in Driving T-Cell Activation and B-Cell Response in Systemic Lupus Erythematosus.

Frontiers in immunology

Zhu H,Hu F,Sun X,Zhang X,Zhu L,Liu X,Li X,Xu L,Shi L,Gan Y,Su Y

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in ELISA

Wed Nov 20 00:00:00 EST 2019

Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL-17 secretion.

Arthritis research & therapy

Noack M,Ndongo-Thiam N,Miossec P

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Thu Jun 23 00:00:00 EDT 2016

Altered expression of miR-92a correlates with Th17 cell frequency in patients with primary biliary cirrhosis.

International journal of molecular medicine

Liang DY,Hou YQ,Luo LJ,Ao L

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Immunofluorescence

Fri Jul 01 00:00:00 EDT 2016

Altered expression of miR-92a correlates with Th17 cell frequency in patients with primary biliary cirrhosis.

International journal of molecular medicine

Liang DY,Hou YQ,Luo LJ,Ao L

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Immunofluorescence

Fri Jul 01 00:00:00 EDT 2016

A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22.

JCI insight

Chang HH,Liu GY,Dwivedi N,Sun B,Okamoto Y,Kinslow JD,Deane KD,Demoruelle MK,Norris JM,Thompson PR,Sparks JA,Rao DA,Karlson EW,Hung HC,Holers VM,Ho IC

13-7179 was used in an ELISA assay to depict a molecular signature of preclinical rheumatoid arthritis that is triggered by impaired induction of PTPN22.

Thu Oct 20 00:00:00 EDT 2016

Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses.

Stem cell reports

Wang WB,Yen ML,Liu KJ,Hsu PJ,Lin MH,Chen PM,Sudhir PR,Chen CH,Chen CH,Sytwu HK,Yen BL

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Tue Sep 08 00:00:00 EDT 2015

Fiber composite slices for multiplexed immunoassays.

Biomicrofluidics

Kim J,Bae S,Song S,Chung K,Kwon S

13-7179 was used in Immuno-assay to describe a new type of low-cost fabrication method for a scalable immunoassay platform based on cotton threads.

Wed Jul 01 00:00:00 EDT 2015

Fiber composite slices for multiplexed immunoassays.

Biomicrofluidics

Kim J,Bae S,Song S,Chung K,Kwon S

13-7179 was used in Immuno-assay to describe a new type of low-cost fabrication method for a scalable immunoassay platform based on cotton threads.

Wed Jul 01 00:00:00 EDT 2015

Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages.

Nature communications

Vogelpoel LT,Hansen IS,Rispens T,Muller FJ,van Capel TM,Turina MC,Vos JB,Baeten DL,Kapsenberg ML,de Jong EC,den Dunnen J

13-7179 was used in Flow cytometry/Cell sorting to show that human M2 macrophages promote inflammation instead of suppressing inflammation on simultaneous exposure to complexed IgG (c-IgG) and TLR ligands.

Thu Nov 13 00:00:00 EST 2014

An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis.

Immunity

Boisson B,Wang C,Pedergnana V,Wu L,Cypowyj S,Rybojad M,Belkadi A,Picard C,Abel L,Fieschi C,Puel A,Li X,Casanova JL

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Thu Oct 17 00:00:00 EDT 2013

Patients with cystic fibrosis have inducible IL-17+IL-22+ memory cells in lung draining lymph nodes.

The Journal of allergy and clinical immunology

Chan YR,Chen K,Duncan SR,Lathrop KL,Latoche JD,Logar AJ,Pociask DA,Wahlberg BJ,Ray P,Ray A,Pilewski JM,Kolls JK

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Immunofluorescence

Mon Apr 01 00:00:00 EDT 2013

Increased frequencies of Th22 cells as well as Th17 cells in the peripheral blood of patients with ankylosing spondylitis and rheumatoid arthritis.

PloS one

Zhang L,Li YG,Li YH,Qi L,Liu XG,Yuan CZ,Hu NW,Ma DX,Li ZF,Yang Q,Li W,Li JM

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Fri Jul 27 00:00:00 EDT 2012

CD5 costimulation induces stable Th17 development by promoting IL-23R expression and sustained STAT3 activation.

Blood

de Wit J,Souwer Y,van Beelen AJ,de Groot R,Muller FJ,Klaasse Bos H,Jorritsma T,Kapsenberg ML,de Jong EC,van Ham SM

13-7179 was used in an ELISA assay to suggest that costimulation via CD5, rather than classic costimulation via CD28, primes naive T cells for stable Th17 development by promoting the expression of IL-23R.

Thu Dec 01 00:00:00 EST 2011

Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis.

The Journal of experimental medicine

Liu L,Okada S,Kong XF,Kreins AY,Cypowyj S,Abhyankar A,Toubiana J,Itan Y,Audry M,Nitschke P,Masson C,Toth B,Flatot J,Migaud M,Chrabieh M,Kochetkov T,Bolze A,Borghesi A,Toulon A,Hiller J,Eyerich S,Eyerich K,Gulácsy V,Chernyshova L,Chernyshov V,Bondarenko A,Grimaldo RM,Blancas-Galicia L,Beas IM,Roesler J,Magdorf K,Engelhard D,Thumerelle C,Burgel PR,Hoernes M,Drexel B,Seger R,Kusuma T,Jansson AF,Sawalle-Belohradsky J,Belohradsky B,Jouanguy E,Bustamante J,Bué M,Karin N,Wildbaum G,Bodemer C,Lortholary O,Fischer A,Blanche S,Al-Muhsen S,Reichenbach J,Kobayashi M,Rosales FE,Lozano CT,Kilic SS,Oleastro M,Etzioni A,Traidl-Hoffmann C,Renner ED,Abel L,Picard C,Maródi L,Boisson-Dupuis S,Puel A,Casanova JL

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Mon Aug 01 00:00:00 EDT 2011

Selective C-Rel activation via Malt1 controls anti-fungal T(H)-17 immunity by dectin-1 and dectin-2.

PLoS pathogens

Gringhuis SI,Wevers BA,Kaptein TM,van Capel TM,Theelen B,Boekhout T,de Jong EC,Geijtenbeek TB

13-7179 was used in an ELISA assay to demonstrate that Malt1 recruitment is pivotal to Th17 immunity by selective activation of c-Rel.

Thu Jan 20 00:00:00 EST 2011

IL-1β and TGF-β act antagonistically in induction and differentially in propagation of human proinflammatory precursor CD4+ T cells.

Journal of immunology (Baltimore, Md. : 1950)

Hebel K,Rudolph M,Kosak B,Chang HD,Butzmann J,Brunner-Weinzierl MC

13-7179 was used in an ELISpot assay to monitor early T cell differentiation after T cell activation in the presence of different inflammatory cytokines.

Thu Dec 01 00:00:00 EST 2011

A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

Kap YS,van Meurs M,van Driel N,Koopman G,Melief MJ,Brok HP,Laman JD,'t Hart BA

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Immunohistochemistry

Tue Dec 01 00:00:00 EST 2009

Interleukin-12 is the optimum cytokine to expand human Th17 cells in vitro.

Clinical and vaccine immunology : CVI

Nady S,Ignatz-Hoover J,Shata MT

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Mon Jun 01 00:00:00 EDT 2009

Interleukin-12 is the optimum cytokine to expand human Th17 cells in vitro.

Clinical and vaccine immunology : CVI

Nady S,Ignatz-Hoover J,Shata MT

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Flow Cytometry

Mon Jun 01 00:00:00 EDT 2009

Prolonged, granulocyte-macrophage colony-stimulating factor-dependent, neutrophil survival following rheumatoid synovial fibroblast activation by IL-17 and TNFalpha.

Arthritis research & therapy

Parsonage G,Filer A,Bik M,Hardie D,Lax S,Howlett K,Church LD,Raza K,Wong SH,Trebilcock E,Scheel-Toellner D,Salmon M,Lord JM,Buckley CD

Published figure using IL-17A monoclonal antibody (Product # 13-7179-81) in Immunofluorescence

Tue Sep 23 00:00:00 EDT 2008

Bioinformatics

Protein Aliases: CTLA-8; Cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; IL-17; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); Interleukin-17A; Interleukin17A; R-IL-17-A

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Gene Aliases: CTLA-8; CTLA8; IL-17; IL-17A; IL17; IL17A

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UniProt ID: (Human) Q16552

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Entrez Gene ID: (Human) 3605

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Function(s)

cytokine activity cytokine receptor binding protein binding

Process(es)

apoptotic process inflammatory response immune response cell surface receptor signaling pathway cell-cell signaling cell death positive regulation of necrotic cell death positive regulation of interleukin-23 production response to amino acid positive regulation of osteoclast differentiation positive regulation of transcription from RNA polymerase II promoter defense response to fungus cellular response to interleukin-1 cellular response to glucocorticoid stimulus fibroblast activation positive regulation of cytokine production involved in inflammatory response positive regulation of interleukin-6 secretion

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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IL-17A Monoclonal Antibody (eBio64DEC17), Biotin, eBioscience™

IL-17A Antibody (13-7179-81) in ICC/IF, IHC

Product Details

13-7179-81

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (Frozen) (IHC (F))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

ELISA (ELISA)

Neutralization (Neu)

Radioimmune Assays (RIA)

Species Reactivity

Published species

Host/Isotype

Recommended Isotype Control

Class

Type

Clone

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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