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14-3-3 eta Antibody (MA5-24792) in ICC/IF
Immunocytochemistry analysis of 14-3-3 eta in HeLa cells. Samples were incubated in 14-3-3 eta monoclonal antibody (Product # MA5-24792) using a dilution of 1:1000. Antibody in red. Blue is DAPI staining of nuclear DNA. The antibody reveals the diffuse cytoplasmic distribution of 14.3.3 protein with higher concentration in the perinuclear region.
Product Details
MA5-24792
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Dog,
Horse,
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3G12
Immunogen
Full length recombinant human 14-3-3 eta.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
5mM sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2717265
Target Information
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 14-3-3 eta; 14-3-3 protein eta; 14-3-3 protein eta chain; 14-3-3 protein eta-like protein; 14-3-3 protein eta-subtype; 1433F; KCIP-1; Protein AS1; Protein kinase C inhibitor protein 1; tyrosine 3-monooxygenase/tryotophan 5-monooxygenase activation protein; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; YWHA114-3-3 eta
Gene Aliases: 14-3-3e; YWHA1; YWHAH
UniProt ID: (Human) Q04917, (Bovine) P70198, (Rat) P68511, (Mouse) P68510
Entrez Gene ID: (Human) 7533, (Dog) 100687866, (Horse) 100062878, (Bovine) 282126, (Rat) 25576, (Mouse) 22629
actin binding
insulin-like growth factor receptor binding
protein binding
sodium channel regulator activity
enzyme binding
protein domain specific binding
glucocorticoid receptor binding
ion channel binding
protein heterodimerization activity
identical protein binding
molecular_function
scaffold/adaptor protein
regulation of sodium ion transport
glucocorticoid catabolic process
intracellular protein transport
substantia nigra development
glucocorticoid receptor signaling pathway
regulation of neuron differentiation
positive regulation of transcription, DNA-templated
regulation of synaptic plasticity
negative regulation of dendrite morphogenesis
membrane organization
membrane depolarization during action potential
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
regulation of sodium ion transmembrane transporter activity
biological_process
cytoskeleton organization
regulation of mitotic nuclear division
negative regulation of apoptotic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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