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Product Details
PA5-17426
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to the sequence of human 14-3-3 tau
Conjugate
Form
Liquid
Concentration
48 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10984345
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 14-3-3 protein T-cell; 14-3-3 protein tau; 14-3-3 protein theta; 14-3-3 tau; 14-3-3 theta; OTTHUMP00000165887; Protein HS1; protein tau; protein, theta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
Gene Aliases: 14-3-3; 14-3-3t; 1C5; 2700028P07Rik; AA409740; AU021156; HS1; R74690; YWHAQ
UniProt ID: (Human) P27348, (Rat) P68255, (Mouse) P68254
Entrez Gene ID: (Human) 10971, (Rat) 25577, (Mouse) 22630
protein targeting
small GTPase mediated signal transduction
substantia nigra development
negative regulation of ion transmembrane transport
negative regulation of transcription, DNA-templated
membrane organization
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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