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Product Details
PA5-22892
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Purified type I human placental 15-PGDH protein.
Conjugate
Form
Liquid
Concentration
1.38 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
4° C, store in dark
Shipping conditions
Wet ice
RRID
AB_11154115
Product Specific Information
Suggested positive control: antigen standard for HPGD (transient overexpression lysate), Treated A549 lung carcinoma cell lysates and LoVo colon carcinoma cell lysates.
Target Information
Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 15-hydroxyprostaglandin dehydrogenase; 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; 15-PGDH; Eicosanoid/docosanoid dehydrogenase [NAD(+)]; NAD+-dependent 15-hydroxyprostaglandin dehydrogenase; NAD-dependent 15-hydroxyprostaglandin dehydrogenase; PGDH; Prostaglandin dehydrogenase 1; Short chain dehydrogenase/reductase family 36C member 1; short chain dehydrogenase/reductase family 36C, member 1
Gene Aliases: 15-PGDH; AV026552; HPGD; PGDH; PGDH1; PHOAR1; SDR36C1
UniProt ID: (Human) P15428, (Rat) O08699, (Mouse) Q61106
Entrez Gene ID: (Human) 3248, (Rat) 79242, (Mouse) 15446
prostaglandin metabolic process
transforming growth factor beta receptor signaling pathway
female pregnancy
parturition
lipoxygenase pathway
ovulation
negative regulation of cell cycle
oxidation-reduction process
thrombin receptor signaling pathway
ductus arteriosus closure
lipoxin metabolic process
lipid metabolic process
fatty acid metabolic process
G-protein coupled receptor signaling pathway
metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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