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Product Details
PA5-34821
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 38 and 260 of 15-PGDH (Uniprot ID#P15428)
Conjugate
Form
Liquid
Concentration
0.69 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2552173
Product Specific Information
Recommended positive controls: 293T.
Predicted reactivity: Mouse (89%), Rat (88%), Dog (93%), Pig (93%), Bovine (91%), Guinea pig (88%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 15-hydroxyprostaglandin dehydrogenase; 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; 15-PGDH; Eicosanoid/docosanoid dehydrogenase [NAD(+)]; NAD+-dependent 15-hydroxyprostaglandin dehydrogenase; PGDH; Prostaglandin dehydrogenase 1; Short chain dehydrogenase/reductase family 36C member 1; short chain dehydrogenase/reductase family 36C, member 1
Gene Aliases: 15-PGDH; AV026552; HPGD; PGDH; PGDH1; PHOAR1; SDR36C1
UniProt ID: (Human) P15428, (Mouse) Q61106
Entrez Gene ID: (Human) 3248, (Mouse) 15446
prostaglandin metabolic process
transforming growth factor beta receptor signaling pathway
female pregnancy
parturition
lipoxygenase pathway
ovulation
negative regulation of cell cycle
oxidation-reduction process
thrombin receptor signaling pathway
ductus arteriosus closure
lipoxin metabolic process
lipid metabolic process
fatty acid metabolic process
G-protein coupled receptor signaling pathway
metabolic process
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