Product References
Zika Virus Infection Induces Interleukin-1β-Mediated Inflammatory Responses by Macrophages in the Brain of an Adult Mouse Model.
Journal of virology
Jeong GU,Lee S,Kim DY,Lyu J,Yoon GY,Kim KD,Ku KB,Ko J,Kwon YC
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 17-7114-80) in Flow Cytometry
Thu Jun 29 00:00:00 EDT 2023
Inhibition of autophagy in microglia and macrophages exacerbates innate immune responses and worsens brain injury outcomes.
Autophagy
Hegdekar N,Sarkar C,Bustos S,Ritzel RM,Hanscom M,Ravishankar P,Philkana D,Wu J,Loane DJ,Lipinski MM
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 17-7114-80) in Flow Cytometry
Sat Jul 01 00:00:00 EDT 2023
Brain innate immune response via miRNA-TLR7 sensing in polymicrobial sepsis.
Brain, behavior, and immunity
Zou L,He J,Gu L,Shahror RA,Li Y,Cao T,Wang S,Zhu J,Huang H,Chen F,Fan X,Wu J,Chao W
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 17-7114-80) in Flow Cytometry
Tue Feb 01 00:00:00 EST 2022
Stimulation of a subset of natural killer T cells by CD103+ DC is required for GM-CSF and protection from pneumococcal infection.
Cell reports
Murray MP,Crosby CM,Marcovecchio P,Hartmann N,Chandra S,Zhao M,Khurana A,Zahner SP,Clausen BE,Coleman FT,Mizgerd JP,Mikulski Z,Kronenberg M
17-7114-80 was used in Flow cytometry/Cell sorting to demonstrate how particular cellular interactions and responses of functional subsets of innate-like T cells contribute to protection from pathogenic lung infection.
Tue Jan 11 00:00:00 EST 2022
Lysosomal acid lipase, CSF1R, and PD-L1 determine functions of CD11c+ myeloid-derived suppressor cells.
JCI insight
Zhao T,Liu S,Ding X,Johnson EM,Hanna NH,Singh K,Sen CK,Wan J,Du H,Yan C
17-7114-80 was used in Flow cytometry/Cell sorting to investigate if CD11c+ cells switched their functions to immune suppression and tumor growth stimulation through CSF1R/PD-L1 upregulation and metabolic reprogramming.
Thu Sep 08 00:00:00 EDT 2022
Neuroinflammation in neuronopathic Gaucher disease: Role of microglia and NK cells, biomarkers, and response to substrate reduction therapy.
eLife
Boddupalli CS,Nair S,Belinsky G,Gans J,Teeple E,Nguyen TH,Mehta S,Guo L,Kramer ML,Ruan J,Wang H,Davison M,Kumar D,Vidyadhara DJ,Zhang B,Klinger K,Mistry PK
17-7114-80 was used in Flow cytometry/Cell sorting to advance nGD disease biology whilst identifying compelling biomarkers of nGD to improve patient management, enrich clinical trials, and illuminate therapeutic targets.
Tue Aug 16 00:00:00 EDT 2022
Nitric oxide controls proliferation of Leishmania major by inhibiting the recruitment of permissive host cells.
Immunity
Formaglio P,Alabdullah M,Siokis A,Handschuh J,Sauerland I,Fu Y,Krone A,Gintschel P,Stettin J,Heyde S,Mohr J,Philipsen L,Schröder A,Robert PA,Zhao G,Khailaie S,Dudeck A,Bertrand J,Späth GF,Kahlfuß S,Bousso P,Schraven B,Huehn J,Binder S,Meyer-Hermann M,Müller AJ
17-7114-80 was used in Flow cytometry/Cell sorting to conclude that NO fulfills two distinct functions for L. major containment: permitting direct killing and restricting the supply of proliferation-permissive host cells.
Tue Dec 14 00:00:00 EST 2021
TNF-Like Ligand 1 Aberrance Aggravates Nonalcoholic Steatohepatitis via M1 Macrophage Polarization.
Oxidative medicine and cellular longevity
Luo Y,Guo J,Jia W,Wu M,Yin F,Niu G,Shih DQ,Targan SR,Zhang X
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 17-7114-80) in Flow Cytometry
Fri Mar 04 00:00:00 EST 2022
NLRP3 Inflammasome Activation of Mast Cells by Estrogen via the Nuclear-Initiated Signaling Pathway Contributes to the Development of Endometriosis.
Frontiers in immunology
Guo X,Xu X,Li T,Yu Q,Wang J,Chen Y,Ding S,Zhu L,Zou G,Zhang X
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 17-7114-80) in Flow Cytometry
Tue Jan 18 00:00:00 EST 2022
MicroRNA-326 attenuates immune escape and prevents metastasis in lung adenocarcinoma by targeting PD-L1 and B7-H3.
Cell death discovery
Shao L,He Q,Wang J,He F,Lin S,Wu L,Gao Y,Ma W,Dong J,Yang X,Li F
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 17-7114-80) in Flow Cytometry
Tue Jun 15 00:00:00 EDT 2021
Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation.
Nature communications
Jones N,Blagih J,Zani F,Rees A,Hill DG,Jenkins BJ,Bull CJ,Moreira D,Bantan AIM,Cronin JG,Avancini D,Jones GW,Finlay DK,Vousden KH,Vincent EE,Thornton CA
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 17-7114-80) in Flow Cytometry
Mon Feb 22 00:00:00 EST 2021
Interleukin-1β Suppresses Gastrin via Primary Cilia and Induces Antral Hyperplasia.
Cellular and molecular gastroenterology and hepatology
Ding L,Sontz EA,Saqui-Salces M,Merchant JL
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 17-7114-80) in Flow Cytometry
Tue Mar 08 00:00:00 EST 2022
β-Glucan-stimulated neutrophil secretion of IL-1α is independent of GSDMD and mediated through extracellular vesicles.
Cell reports
Ratitong B,Marshall M,Pearlman E
17-7114-80 was used in Flow Cytometry to identify neutrophils as a source of IL-1α and demonstrate a role for EVs, specifically exosomes, in neutrophil secretion of bioactive IL-1α.
Tue May 18 00:00:00 EDT 2021
Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway.
Journal of neuroinflammation
Duan RN,Yang CL,Du T,Liu A,Wang AR,Sun WJ,Li X,Li JX,Yan CZ,Liu QJ
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 17-7114-80) in Flow Cytometry
Mon Jun 28 00:00:00 EDT 2021
NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8+ T cell responses.
iScience
Souza COS,Ketelut-Carneiro N,Milanezi CM,Faccioli LH,Gardinassi LG,Silva JS
17-7114-80 was used in Flow Cytometry to investigate if NLRC4 promotes disease by regulating the production of inflammatory cytokines and cellular responses that depend on the NLRP3 inflammasome activity.
Fri Jun 25 00:00:00 EDT 2021
GM-CSF production by non-classical monocytes controls antagonistic LPS-driven functions in allergic inflammation.
Cell reports
Kaur K,Bachus H,Lewis C,Papillion AM,Rosenberg AF,Ballesteros-Tato A,León B
17-7114-80 was used in Flow cytometry/Cell sorting to show here that lipopolysaccharide activity switches from pro-pathogenic to protective depending on the production of granulocyte-macrophage colony-stimulating factor by non-classical monocytes.
Tue Dec 28 00:00:00 EST 2021
Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells.
Cell metabolism
Rosser EC,Piper CJM,Matei DE,Blair PA,Rendeiro AF,Orford M,Alber DG,Krausgruber T,Catalan D,Klein N,Manson JJ,Drozdov I,Bock C,Wedderburn LR,Eaton S,Mauri C
17-7114 was used in Flow cytometry/Cell sorting to investigate butyrate supplementation as a potential therapy for the amelioration of systemic autoimmune disorders.
Tue Apr 07 00:00:00 EDT 2020
Legionella-Infected Macrophages Engage the Alveolar Epithelium to Metabolically Reprogram Myeloid Cells and Promote Antibacterial Inflammation.
Cell host & microbe
Liu X,Boyer MA,Holmgren AM,Shin S
17-7114-80 was used in Flow Cytometry to reveal that alveolar macrophages engage alveolar epithelial signals to metabolically reprogram monocytes for antibacterial inflammation.
Wed Nov 11 00:00:00 EST 2020
T cells instruct myeloid cells to produce inflammasome-independent IL-1β and cause autoimmunity.
Nature immunology
Jain A,Irizarry-Caro RA,McDaniel MM,Chawla AS,Carroll KR,Overcast GR,Philip NH,Oberst A,Chervonsky AV,Katz JD,Pasare C
17-7114 was used in Flow cytometry/Cell sorting to describe an inflammasome-independent pathway of IL-1β production that was triggered upon cognate interactions between effector CD4+ T cells and mononuclear phagocytes.
Wed Jan 01 00:00:00 EST 2020
Hippocampal interleukin-33 mediates neuroinflammation-induced cognitive impairments.
Journal of neuroinflammation
Reverchon F,de Concini V,Larrigaldie V,Benmerzoug S,Briault S,Togbé D,Ryffel B,Quesniaux VFJ,Menuet A
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 17-7114-80) in Flow Cytometry
Fri Sep 11 00:00:00 EDT 2020
Triacylglycerol synthesis enhances macrophage inflammatory function.
Nature communications
Castoldi A,Monteiro LB,van Teijlingen Bakker N,Sanin DE,Rana N,Corrado M,Cameron AM,Hässler F,Matsushita M,Caputa G,Klein Geltink RI,Büscher J,Edwards-Hicks J,Pearce EL,Pearce EJ
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 17-7114-80) in Flow Cytometry
Fri Aug 14 00:00:00 EDT 2020
Heme Oxygenase-1 Induction by Blood-Feeding Arthropods Controls Skin Inflammation and Promotes Disease Tolerance.
Cell reports
DeSouza-Vieira T,Iniguez E,Serafim TD,de Castro W,Karmakar S,Disotuar MM,Cecilio P,Lacsina JR,Meneses C,Nagata BM,Cardoso S,Sonenshine DE,Moore IN,Borges VM,Dey R,Soares MP,Nakhasi HL,Oliveira F,Valenzuela JG,Kamhawi S
17-7114 was used in Flow cytometry/Cell sorting to demonstrate that HO-1 induction through erythrophagocytosis is a universal mechanism that regulates skin inflammation following blood feeding by arthropods, thus promoting early-stage disease tolerance to vector-borne pathogens.
Tue Oct 27 00:00:00 EDT 2020
GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation.
Cell reports
Castro-Dopico T,Fleming A,Dennison TW,Ferdinand JR,Harcourt K,Stewart BJ,Cader Z,Tuong ZK,Jing C,Lok LSC,Mathews RJ,Portet A,Kaser A,Clare S,Clatworthy MR
17-7114 was used in Flow cytometry/Cell sorting to identify granulocyte-macrophage colony stimulating factor (GM-CSF) as a critical regulator of intestinal macrophage activation in patients with IBD and mice with dextran sodium sulfate (DSS)-induced colitis.
Tue Jul 07 00:00:00 EDT 2020
Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.
Immunity
Castro-Dopico T,Dennison TW,Ferdinand JR,Mathews RJ,Fleming A,Clift D,Stewart BJ,Jing C,Strongili K,Labzin LI,Monk EJM,Saeb-Parsy K,Bryant CE,Clare S,Parkes M,Clatworthy MR
17-7114-80 was used in Flow cytometry/Cell sorting to understand the mechanisms whereby changes in FcγRIIA affinity would affect inflammation in an IgA-dominated organ.
Tue Apr 16 00:00:00 EDT 2019
Toxin-Triggered Interleukin-1 Receptor Signaling Enables Early-Life Discrimination of Pathogenic versus Commensal Skin Bacteria.
Cell host & microbe
Leech JM,Dhariwala MO,Lowe MM,Chu K,Merana GR,Cornuot C,Weckel A,Ma JM,Leitner EG,Gonzalez JR,Vasquez KS,Diep BA,Scharschmidt TC
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 17-7114-80) in Flow Cytometry
Wed Dec 11 00:00:00 EST 2019
Reprogramming the adjuvant properties of aluminum oxyhydroxide with nanoparticle technology.
NPJ vaccines
Orr MT,Khandhar AP,Seydoux E,Liang H,Gage E,Mikasa T,Beebe EL,Rintala ND,Persson KH,Ahniyaz A,Carter D,Reed SG,Fox CB
17-7114 was used in Flow cytometry/Cell sorting to determine whether the particle size and aggregated state of aluminum oxyhydroxide affects its adjuvant activity.
Thu Oct 01 00:00:00 EDT 2020
1,25-Dihydroxyvitamin D suppresses M1 macrophages and promotes M2 differentiation at bone injury sites.
JCI insight
Wasnik S,Rundle CH,Baylink DJ,Yazdi MS,Carreon EE,Xu Y,Qin X,Lau KW,Tang X
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 17-7114-80) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
Notch Regulates Macrophage-Mediated Inflammation in Diabetic Wound Healing.
Frontiers in immunology
Kimball AS,Joshi AD,Boniakowski AE,Schaller M,Chung J,Allen R,Bermick J,Carson WF,Henke PK,Maillard I,Kunkel SL,Gallagher KA
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 17-7114-80) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Depletion of microglia exacerbates postischemic inflammation and brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Jin WN,Shi SX,Li Z,Li M,Wood K,Gonzales RJ,Liu Q
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 17-7114-80) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
Dendritic cells, macrophages, NK and CD8+ T lymphocytes play pivotal roles in controlling HSV-1 in the trigeminal ganglia by producing IL1-beta, iNOS and granzyme B.
Virology journal
Lucinda N,Figueiredo MM,Pessoa NL,Santos BS,Lima GK,Freitas AM,Machado AM,Kroon EG,Antonelli LR,Campos MA
17-7114 was used in Flow cytometry/Cell sorting to provide strong evidence that the responses mediated by DCs, Mo/M?, NK and CD8+ T lymphocytes through IL-1β, iNOS and granzyme B production, respectively, together with the production of type I IFN early in the infection, are crucial to host defense against HSV-1.
Tue Feb 21 00:00:00 EST 2017
The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation.
Nature
Ravindran R,Loebbermann J,Nakaya HI,Khan N,Ma H,Gama L,Machiah DK,Lawson B,Hakimpour P,Wang YC,Li S,Sharma P,Kaufman RJ,Martinez J,Pulendran B
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 17-7114-80) in Flow Cytometry
Thu Mar 24 00:00:00 EDT 2016
Blockade of MK2 is protective in inflammation-associated colorectal cancer development.
International journal of cancer
Ray AL,Castillo EF,Morris KT,Nofchissey RA,Weston LL,Samedi VG,Hanson JA,Gaestel M,Pinchuk IV,Beswick EJ
17-7114 was used in Flow cytometry/Cell sorting to investigate the role of MAPK-activated protein kinase 2 in development of colitis-associated colon cancer.
Mon Feb 01 00:00:00 EST 2016
Neutrophils Oppose Uterine Epithelial Carcinogenesis via Debridement of Hypoxic Tumor Cells.
Cancer cell
Blaisdell A,Crequer A,Columbus D,Daikoku T,Mittal K,Dey SK,Erlebacher A
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 17-7114-80) in Flow Cytometry
Mon Dec 14 00:00:00 EST 2015
Differential Immunometabolic Phenotype in Th1 and Th2 Dominant Mouse Strains in Response to High-Fat Feeding.
PloS one
Jovicic N,Jeftic I,Jovanovic I,Radosavljevic G,Arsenijevic N,Lukic ML,Pejnovic N
17-7114 was used in Flow cytometry/Cell sorting to investigate the onset of obesity-associated metabolic diseases in two mouse strains with different immune phenotypes.
Tue May 03 00:00:00 EDT 2016
Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity.
Nature medicine
Kim HY,Lee HJ,Chang YJ,Pichavant M,Shore SA,Fitzgerald KA,Iwakura Y,Israel E,Bolger K,Faul J,DeKruyff RH,Umetsu DT
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 17-7114-80) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2014
Cell-selective inhibition of NF-κB signaling improves therapeutic index in a melanoma chemotherapy model.
Cancer discovery
Enzler T,Sano Y,Choo MK,Cottam HB,Karin M,Tsao H,Park JM
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 17-7114-80) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2011