Invitrogen

CD105 (Endoglin) Monoclonal Antibody (SN6), PE-Cyanine7, eBioscience™

CD105 (Endoglin) Antibody in Flow Cytometry (Flow)

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CD105 (Endoglin) Antibody (25-1057-42) in Flow

Staining of U937 cells with Mouse IgG1 K Isotype Control PE-Cyanine7 (Product # 25-4714-80) (blue histogram) or Anti-Human CD105 (Endoglin) PE-Cyanine7 (purple histogram). Total viable cells, as determined by Fixable Viability Dye eFluor® 780, were used for analysis.

Product Image Gallery

Product Details

25-1057-42

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

5 µL (0.125 µg)/test

View 57 publications 57 publications

Product Specifications

Species Reactivity

Human

Published species

Cat, Dog, Fruit fly, Human

Host/Isotype

Mouse / IgG1, kappa

Recommended Isotype Control

Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), PE-Cyanine7, eBioscience™

Class

Monoclonal

Type

Antibody

Clone

SN6

Conjugate

PE-Cyanine7 PE-Cyanine7 PE-Cyanine7

Excitation/Emission Max

569/780 nm View spectra

Form

Liquid

Concentration

5 µL/Test

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with 0.2% BSA

Contains

0.09% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11217682

Product Specific Information

Description: The SN6 monoclonal antibody reacts with human CD105, also known as Endoglin. CD105, an approximately 90 kDa disulfide-linked homodimer is expressed by vascular endothelial cells and some bone marrow cells and activated macrophages. It is suggested that CD105 functions in adhesion and embryonic angiogenesis.

Applications Reported: This SN6 antibody has been reported for use in flow cytometric analysis.

Applications Tested: This SN6 antibody has been pre-titrated and tested by flow cytometric analysis of the U937 cell line. This can be used at 5 µL (0.125 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

Light sensitivity: This tandem dye is sensitive photo-induced oxidation. Please protect this vial and stained samples from light.

Fixation: Samples can be stored in IC Fixation Buffer (Product # 00-822-49) (100 µL cell sample + 100 µL IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product # 00-5333-54) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically.

Excitation: 488-561 nm; Emission: 775 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.

Filtration: 0.2 µm post-manufacturing filtered.

Target Information

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

Product References

Enhanced chondrogenic differentiation of iPS cell-derived mesenchymal stem/stromal cells via neural crest cell induction for hyaline cartilage repair.

Frontiers in cell and developmental biology

Zujur D,Al-Akashi Z,Nakamura A,Zhao C,Takahashi K,Aritomi S,Theoputra W,Kamiya D,Nakayama K,Ikeya M

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Sun May 28 00:00:00 EDT 2023

Exercise combined with administration of adipose-derived stem cells ameliorates neuropathic pain after spinal cord injury.

Neural regeneration research

Cheng X,Mao GP,Hu WJ,Yu ZR,Xu YY,Chen W,Li X,Zeng XL,Zhang WW,Chen JW,Wan Y,Wang L

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Tue Aug 01 00:00:00 EDT 2023

Exosomes derived from stem cells of human deciduous exfoliated teeth inhibit angiogenesis in vivo and in vitro via the transfer of miR-100-5p and miR-1246.

Stem cell research & therapy

Liu P,Zhang Q,Mi J,Wang S,Xu Q,Zhuang D,Chen W,Liu C,Zhang L,Guo J,Wu X

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Thu Mar 03 00:00:00 EST 2022

Production enhancement of human adipose-derived mesenchymal stem cells by low-intensity ultrasound stimulation.

Scientific reports

Min S,Byeon Y,Kim M,Lee Y,Lee SH,Lee Y,Farooqi HMU,Lee HK,Paeng DG

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Wed Dec 21 00:00:00 EST 2022

Isolation and characterization mesenchymal stem cells from red panda (Ailurus fulgens styani) endometrium.

Conservation physiology

Wang DH,Wu XM,Chen JS,Cai ZG,An JH,Zhang MY,Li Y,Li FP,Hou R,Liu YL

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Sat Jan 01 00:00:00 EST 2022

Induced Neurodifferentiation of hBM-MSCs through Activation of the ERK/CREB Pathway via Pulsed Electromagnetic Fields and Physical Stimulation Promotes Neurogenesis in Cerebral Ischemic Models.

International journal of molecular sciences

Park HJ,Choi JH,Nam MH,Seo YK

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Fri Jan 21 00:00:00 EST 2022

Mesenchymal stem cells derived from patients with premature aging syndromes display hallmarks of physiological aging.

Life science alliance

Trani JP,Chevalier R,Caron L,El Yazidi C,Broucqsault N,Toury L,Thomas M,Annab K,Binetruy B,De Sandre-Giovannoli A,Levy N,Magdinier F,Robin JD

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Wed Sep 14 00:00:00 EDT 2022

Aberrant Expression of COX-2 and FOXG1 in Infrapatellar Fat Pad-Derived ASCs from Pre-Diabetic Donors.

Cells

O'Donnell BT,Monjure TA,Al-Ghadban S,Ives CJ,L'Ecuyer MP,Rhee C,Romero-Lopez M,Li Z,Goodman SB,Lin H,Tuan RS,Bunnell BA

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Mon Aug 01 00:00:00 EDT 2022

TRPA1 triggers hyperalgesia and inflammation after tooth bleaching.

Scientific reports

Chen C,Huang X,Zhu W,Ding C,Huang P,Li R

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Tue Aug 31 00:00:00 EDT 2021

Development, characterization, and hematopoietic differentiation of Griscelli syndrome type 2 induced pluripotent stem cells.

Stem cell research & therapy

Güney-Esken G,Erol ÖD,Pervin B,Gürhan Sevinç G,Önder T,Bilgiç E,Korkusuz P,Günel-Özcan A,Uçkan-Çetinkaya D,Aerts-Kaya F

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Thu May 13 00:00:00 EDT 2021

Human Amniotic Mesenchymal Stem Cells Inhibit aGVHD by Regulating Balance of Treg and T Effector Cells.

Journal of inflammation research

Gao Y,Li W,Bu X,Xu Y,Cai S,Zhong J,Du M,Sun H,Huang L,He Y,Hu X,Liu Q,Jin H,Wang Q,Ping B

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Tue Apr 26 00:00:00 EDT 2022

Therapeutic potential of human umbilical cord mesenchymal stem cells on aortic atherosclerotic plaque in a high-fat diet rabbit model.

Stem cell research & therapy

Li Y,Shi G,Han Y,Shang H,Li H,Liang W,Zhao W,Bai L,Qin C

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Thu Jul 15 00:00:00 EDT 2021

ZKSCAN3 counteracts cellular senescence by stabilizing heterochromatin.

Nucleic acids research

Hu H,Ji Q,Song M,Ren J,Liu Z,Wang Z,Liu X,Yan K,Hu J,Jing Y,Wang S,Zhang W,Liu GH,Qu J

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Fri Jun 19 00:00:00 EDT 2020

Rescue of premature aging defects in Cockayne syndrome stem cells by CRISPR/Cas9-mediated gene correction.

Protein & cell

Wang S,Min Z,Ji Q,Geng L,Su Y,Liu Z,Hu H,Wang L,Zhang W,Suzuiki K,Huang Y,Zhang P,Tang TS,Qu J,Yu Y,Liu GH,Qiao J

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Wed Jan 01 00:00:00 EST 2020

Down-Regulated Exosomal MicroRNA-221 - 3p Derived From Senescent Mesenchymal Stem Cells Impairs Heart Repair.

Frontiers in cell and developmental biology

Sun L,Zhu W,Zhao P,Zhang J,Lu Y,Zhu Y,Zhao W,Liu Y,Chen Q,Zhang F

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Mon Sep 28 00:00:00 EDT 2020

Differentiation Potential of Early- and Late-Passage Adipose-Derived Mesenchymal Stem Cells Cultured under Hypoxia and Normoxia.

Stem cells international

Zhao AG,Shah K,Freitag J,Cromer B,Sumer H

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Tue Oct 06 00:00:00 EDT 2020

Resveratrol rescues TNF‑α‑induced inhibition of osteogenesis in human periodontal ligament stem cells via the ERK1/2 pathway.

Molecular medicine reports

Yuan J,Wang X,Ma D,Gao H,Zheng D,Zhang J

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Fri May 01 00:00:00 EDT 2020

Vasculogenesis from Human Dental Pulp Stem Cells Grown in Matrigel with Fully Defined Serum-Free Culture Media.

Biomedicines

Luzuriaga J,Irurzun J,Irastorza I,Unda F,Ibarretxe G,Pineda JR

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Mon Nov 09 00:00:00 EST 2020

PF-127 hydrogel plus sodium ascorbyl phosphate improves Wharton's jelly mesenchymal stem cell-mediated skin wound healing in mice.

Stem cell research & therapy

Deng Q,Huang S,Wen J,Jiao Y,Su X,Shi G,Huang J

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Fri Apr 03 00:00:00 EDT 2020

Chondrogenic Differentiation from Induced Pluripotent Stem Cells Using Non-Viral Minicircle Vectors.

Cells

Rim YA,Nam Y,Park N,Jung H,Lee K,Lee J,Ju JH

25-1057 was used in Flow cytometry/Cell sorting to explore the use of minicircle vectors in cartilage regeneration using human induced pluripotent stem cells.

Sun Mar 01 00:00:00 EST 2020

Chondrogenic Differentiation from Induced Pluripotent Stem Cells Using Non-Viral Minicircle Vectors.

Cells

Rim YA,Nam Y,Park N,Jung H,Lee K,Lee J,Ju JH

25-1057 was used in Flow cytometry/Cell sorting to explore the use of minicircle vectors in cartilage regeneration using human induced pluripotent stem cells.

Sun Mar 01 00:00:00 EST 2020

The Effect of Angiotensin II, Retinoic Acid, EGCG, and Vitamin C on the Cardiomyogenic Differentiation Induction of Human Amniotic Fluid-Derived Mesenchymal Stem Cells.

International journal of molecular sciences

Gasiūnienė M,Valatkaitė E,Navakauskaitė A,Navakauskienė R

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Thu Nov 19 00:00:00 EST 2020

Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages.

Stem cell research & therapy

Liu J,Qiu X,Lv Y,Zheng C,Dong Y,Dou G,Zhu B,Liu A,Wang W,Zhou J,Liu S,Liu S,Gao B,Jin Y

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Fri Nov 27 00:00:00 EST 2020

Comparison of Canine and Feline Adipose-Derived Mesenchymal Stem Cells/Medicinal Signaling Cells With Regard to Cell Surface Marker Expression, Viability, Proliferation, and Differentiation Potential.

Frontiers in veterinary science

Voga M,Kovač V,Majdic G

25-1057-42 was used in Flow cytometry/Cell sorting to examine the viability of cells measured by two different methods at passage 3 differed between the species, and finally, canine ADMSCs possess greater proliferation and differentiation potential in comparison to the feline ADMSCs.

Tue Feb 02 00:00:00 EST 2021

Telomere-dependent and telomere-independent roles of RAP1 in regulating human stem cell homeostasis.

Protein & cell

Zhang X,Liu Z,Liu X,Wang S,Zhang Y,He X,Sun S,Ma S,Shyh-Chang N,Liu F,Wang Q,Wang X,Liu L,Zhang W,Song M,Liu GH,Qu J

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Sun Sep 01 00:00:00 EDT 2019

Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis.

PLoS biology

Fu L,Hu Y,Song M,Liu Z,Zhang W,Yu FX,Wu J,Wang S,Izpisua Belmonte JC,Chan P,Qu J,Tang F,Liu GH

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Mon Apr 01 00:00:00 EDT 2019

Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.

Stem cells international

Sun B,Luo X,Yang C,Liu P,Yang Y,Dong X,Yang Z,Xu J,Zhang Y,Li L

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Thu May 13 00:00:00 EDT 2021

TGF‑β induces periodontal ligament stem cell senescence through increase of ROS production.

Molecular medicine reports

Fan C,Ji Q,Zhang C,Xu S,Sun H,Li Z

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Tue Oct 01 00:00:00 EDT 2019

Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis.

Nature communications

Deng L,Ren R,Liu Z,Song M,Li J,Wu Z,Ren X,Fu L,Li W,Zhang W,Guillen P,Izpisua Belmonte JC,Chan P,Qu J,Liu GH

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Fri Jul 26 00:00:00 EDT 2019

Visfatin Mediates Malignant Behaviors through Adipose-Derived Stem Cells Intermediary in Breast Cancer.

Cancers

Huang JY,Wang YY,Lo S,Tseng LM,Chen DR,Wu YC,Hou MF,Yuan SF

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Fri Dec 20 00:00:00 EST 2019

Better therapeutic potential of bone marrow-derived mesenchymal stem cells compared with chorionic villi-derived mesenchymal stem cells in airway injury model.

Regenerative medicine

Ji S,Wu C,Tong L,Wang L,Zhou J,Chen C,Song Y

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Fri Mar 01 00:00:00 EST 2019

Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome.

Protein & cell

Wu Z,Zhang W,Song M,Wang W,Wei G,Li W,Lei J,Huang Y,Sang Y,Chan P,Chen C,Qu J,Suzuki K,Belmonte JCI,Liu GH

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Sun Apr 01 00:00:00 EDT 2018

Antagonizing CD105 enhances radiation sensitivity in prostate cancer.

Oncogene

Madhav A,Andres A,Duong F,Mishra R,Haldar S,Liu Z,Angara B,Gottlieb R,Zumsteg ZS,Bhowmick NA

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Wed Aug 01 00:00:00 EDT 2018

Human umbilical cord-derived mesenchymal stem cells ameliorate the enteropathy of food allergies in mice.

Experimental and therapeutic medicine

Yan N,Xu J,Zhao C,Wu Y,Gao F,Li C,Zhou W,Xiao T,Zhou X,Shao Q,Xia S

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Sat Dec 01 00:00:00 EST 2018

ATF6 safeguards organelle homeostasis and cellular aging in human mesenchymal stem cells.

Cell discovery

Wang S,Hu B,Ding Z,Dang Y,Wu J,Li D,Liu X,Xiao B,Zhang W,Ren R,Lei J,Hu H,Chen C,Chan P,Li D,Qu J,Tang F,Liu GH

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Thu Oct 01 00:00:00 EDT 2020

Immunosuppressive Mesenchymal Stromal Cells Derived from Human-Induced Pluripotent Stem Cells Induce Human Regulatory T Cells In Vitro and In Vivo.

Frontiers in immunology

Roux C,Saviane G,Pini J,Belaïd N,Dhib G,Voha C,Ibáñez L,Boutin A,Mazure NM,Wakkach A,Blin-Wakkach C,Rouleau M

25-1057 was used in Flow cytometry/Cell sorting to examine the immunosuppressive activity of human induced pluripotent stem cell derived-mesenchymal stromal cells on human T-cell stimulation with a concomitant generation of human regulatory T cells in vivo.

Wed Nov 20 00:00:00 EST 2019

Transplantation of betatrophin-expressing adipose-derived mesenchymal stem cells induces β-cell proliferation in diabetic mice.

International journal of molecular medicine

Sun LL,Liu TJ,Li L,Tang W,Zou JJ,Chen XF,Zheng JY,Jiang BG,Shi YQ

25-1057 was used in Flow cytometry/Cell sorting to demonstrate a novel, betatrophin-based strategy for inducing β-cell regeneration.

Sat Apr 01 00:00:00 EDT 2017

The Improvement of Respiratory Performance After Phototherapy-Induced EPC Mobilization in Preterm Infants With RDS.

Journal of cellular biochemistry

Siavashi V,Asadian S,Taheri-Asl M,Babaei H,Keshavarz S,Bazaei M,Nassiri SM

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2017

Circulation Enrichment of Functional Endothelial Progenitor Cells by Infantile Phototherapy.

Journal of cellular biochemistry

Siavashi V,Asadian S,Sharifi A,Esmaeilivand M,Norouzinia R,Azadbakht M,Nassiri SM

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Wed Feb 01 00:00:00 EST 2017

Human umbilical cord mesenchymal stem cells improve the reserve function of perimenopausal ovary via a paracrine mechanism.

Stem cell research & therapy

Li J,Mao Q,He J,She H,Zhang Z,Yin C

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Thu Mar 09 00:00:00 EST 2017

Adenovirus-Mediated Expression of BMP-2 and BFGF in Bone Marrow Mesenchymal Stem Cells Combined with Demineralized Bone Matrix For Repair of Femoral Head Osteonecrosis in Beagle Dogs.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Peng WX,Wang L

25-1057 was used in Flow cytometry/Cell sorting to indicate that the use of Ad-BMP-2/bFGF-modified BMSCs in conjunction with DBM could successfully repair ONFH in a dog model by promoting bone formation and angiogenesis.

Mon Dec 18 00:00:00 EST 2017

Etanercept-Synthesising Mesenchymal Stem Cells Efficiently Ameliorate Collagen-Induced Arthritis.

Scientific reports

Park N,Rim YA,Jung H,Kim J,Yi H,Kim Y,Jang Y,Jung SM,Lee J,Kwok SK,Park SH,Ju JH

25-1057 was used in Flow cytometry/Cell sorting to develop a novel method to produce synthetic biological drugs from engineered MSCs, and investigate the anti-arthritic effect of these cells in a collagen-induced arthritis mouse model.

Fri Jan 13 00:00:00 EST 2017

SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2.

Cell research

Pan H,Guan D,Liu X,Li J,Wang L,Wu J,Zhou J,Zhang W,Ren R,Zhang W,Li Y,Yang J,Hao Y,Yuan T,Yuan G,Wang H,Ju Z,Mao Z,Li J,Qu J,Tang F,Liu GH

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Mon Feb 01 00:00:00 EST 2016

Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification.

Annals of surgery

Loder S,Agarwal S,Sorkin M,Breuler C,Li J,Peterson J,Gardenier J,Hsieh HH,Wang SC,Mehrara BJ,Levi B

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Thu Dec 01 00:00:00 EST 2016

A Member of the Nuclear Receptor Superfamily, Designated as NR2F2, Supports the Self-Renewal Capacity and Pluripotency of Human Bone Marrow-Derived Mesenchymal Stem Cells.

Stem cells international

Zhu N,Wang H,Wang B,Wei J,Shan W,Feng J,Huang H

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Tue Jan 19 00:00:00 EST 2016

Angiogenic activity mediates bone repair from human pluripotent stem cell-derived osteogenic cells.

Scientific reports

Zou L,Chen Q,Quanbeck Z,Bechtold JE,Kaufman DS

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Wed Mar 16 00:00:00 EDT 2016

Influence of aging on the quantity and quality of human cardiac stem cells.

Scientific reports

Nakamura T,Hosoyama T,Kawamura D,Takeuchi Y,Tanaka Y,Samura M,Ueno K,Nishimoto A,Kurazumi H,Suzuki R,Ito H,Sakata K,Mikamo A,Li TS,Hamano K

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Mon Mar 07 00:00:00 EST 2016

MIF Plays a Key Role in Regulating Tissue-Specific Chondro-Osteogenic Differentiation Fate of Human Cartilage Endplate Stem Cells under Hypoxia.

Stem cell reports

Yao Y,Deng Q,Song W,Zhang H,Li Y,Yang Y,Fan X,Liu M,Shang J,Sun C,Tang Y,Jin X,Liu H,Huang B,Zhou Y

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Tue Aug 09 00:00:00 EDT 2016

CRISPR/Cas9-based genetic correction for recessive dystrophic epidermolysis bullosa.

NPJ Regenerative medicine

Webber BR,Osborn MJ,McElroy AN,Twaroski K,Lonetree CL,DeFeo AP,Xia L,Eide C,Lees CJ,McElmurry RT,Riddle MJ,Kim CJ,Patel DD,Blazar BR,Tolar J

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Wed Sep 30 00:00:00 EDT 2020

Spontaneous Differentiation of Human Mesenchymal Stem Cells on Poly-Lactic-Co-Glycolic Acid Nano-Fiber Scaffold.

PloS one

Sonomoto K,Yamaoka K,Kaneko H,Yamagata K,Sakata K,Zhang X,Kondo M,Zenke Y,Sabanai K,Nakayamada S,Sakai A,Tanaka Y

25-1057 was used in Flow cytometry/Cell sorting to investigate the combination of MSCs and NFs as a therapeutic technique for the repair of joints affected by bone and cartilage destruction.

Thu Sep 01 00:00:00 EDT 2016

Modeling familial cancer with induced pluripotent stem cells.

Cell

Lee DF,Su J,Kim HS,Chang B,Papatsenko D,Zhao R,Yuan Y,Gingold J,Xia W,Darr H,Mirzayans R,Hung MC,Schaniel C,Lemischka IR

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Thu Apr 09 00:00:00 EDT 2015

Impaired function of bone marrow stromal cells in systemic mastocytosis.

Stem cell research

Nemeth K,Wilson TM,Ren JJ,Sabatino M,Stroncek DM,Krepuska M,Bai Y,Robey PG,Metcalfe DD,Mezey E

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Wed Jul 01 00:00:00 EDT 2015

Human adipose-derived stem cells partially rescue the stroke syndromes by promoting spatial learning and memory in mouse middle cerebral artery occlusion model.

Stem cell research & therapy

Zhou F,Gao S,Wang L,Sun C,Chen L,Yuan P,Zhao H,Yi Y,Qin Y,Dong Z,Cao L,Ren H,Zhu L,Li Q,Lu B,Liang A,Xu GT,Zhu H,Gao Z,Ma J,Xu J,Chen X

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Sat May 09 00:00:00 EDT 2015

Human Gingival Integration-Free iPSCs; a Source for MSC-Like Cells.

International journal of molecular sciences

Umezaki Y,Hashimoto Y,Nishishita N,Kawamata S,Baba S

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Mon Jun 15 00:00:00 EDT 2015

Serum- and growth-factor-free three-dimensional culture system supports cartilage tissue formation by promoting collagen synthesis via Sox9-Col2a1 interaction.

Tissue engineering. Part A

Ahmed N,Iu J,Brown CE,Taylor DW,Kandel RA

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Fri Aug 01 00:00:00 EDT 2014

Epithelial cell differentiation of human mesenchymal stromal cells in decellularized lung scaffolds.

Tissue engineering. Part A

Mendez JJ,Ghaedi M,Steinbacher D,Niklason LE

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Sun Jun 01 00:00:00 EDT 2014

Hypoxia-cultured human adipose-derived mesenchymal stem cells are non-oncogenic and have enhanced viability, motility, and tropism to brain cancer.

Cell death & disease

Feng Y,Zhu M,Dangelmajer S,Lee YM,Wijesekera O,Castellanos CX,Denduluri A,Chaichana KL,Li Q,Zhang H,Levchenko A,Guerrero-Cazares H,Quiñones-Hinojosa A

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Thu Dec 11 00:00:00 EST 2014

Early intervention with gene-modified mesenchymal stem cells overexpressing interleukin-4 enhances anti-inflammatory responses and functional recovery in experimental autoimmune demyelination.

Cell adhesion & migration

Payne NL,Dantanarayana A,Sun G,Moussa L,Caine S,McDonald C,Herszfeld D,Bernard CC,Siatskas C

Published figure using CD105 (Endoglin) monoclonal antibody (Product # 25-1057-42) in Flow Cytometry

Wed Dec 19 00:00:00 EST 2012

Bioinformatics

Protein Aliases: CD105; CD105 antigen; Endoglin; ORW

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Gene Aliases: END; ENG; HHT1; ORW1

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UniProt ID: (Human) P17813

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Entrez Gene ID: (Human) 2022

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Function(s)

transmembrane signaling receptor activity transforming growth factor beta receptor, cytoplasmic mediator activity type II transforming growth factor beta receptor binding protein binding galactose binding glycosaminoglycan binding type I transforming growth factor beta receptor binding BMP binding protein homodimerization activity activin binding transforming growth factor beta binding transmembrane signal receptor

Process(es)

chronological cell aging patterning of blood vessels vasculogenesis positive regulation of protein phosphorylation heart looping sprouting angiogenesis endocardial cushion morphogenesis cardiac ventricle morphogenesis cardiac atrium morphogenesis ventricular trabecula myocardium morphogenesis cell migration involved in endocardial cushion formation regulation of transcription, DNA-templated cell adhesion negative regulation of gene expression positive regulation of pathway-restricted SMAD protein phosphorylation regulation of transforming growth factor beta receptor signaling pathway central nervous system vasculogenesis negative regulation of cell migration BMP signaling pathway positive regulation of BMP signaling pathway negative regulation of protein autophosphorylation dorsal aorta morphogenesis positive regulation of angiogenesis positive regulation of transcription from RNA polymerase II promoter smooth muscle tissue development artery morphogenesis venous blood vessel morphogenesis endocardial cushion to mesenchymal transition positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

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CD105 (Endoglin) Monoclonal Antibody (SN6), PE-Cyanine7, eBioscience™

CD105 (Endoglin) Antibody (25-1057-42) in Flow

Product Details

25-1057-42

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