Product References
RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation.
Acta neuropathologica
Kim YA,Siddiqui T,Blaze J,Cosacak MI,Winters T,Kumar A,Tein E,Sproul AA,Teich AF,Bartolini F,Akbarian S,Kizil C,Hargus G,Santa-Maria I
44-750G was used in Western Blot to indicate that neuronal NSun2 deficiency promotes dysregulation of miR-125b and tau phosphorylation in AD and highlights a novel avenue for therapeutic targeting.
Sun Jan 01 00:00:00 EST 2023
Toxicities of amyloid-beta and tau protein are reciprocally enhanced in the Drosophila model.
Neural regeneration research
Sun ZD,Hu JX,Wu JR,Zhou B,Huang YP
Published figure using Phospho-Tau (Ser262) polyclonal antibody (Product # 44-750G) in Western Blot
Sat Oct 01 00:00:00 EDT 2022
Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy.
Molecular neurodegeneration
Brody AH,Nies SH,Guan F,Smith LM,Mukherjee B,Salazar SA,Lee S,Lam TKT,Strittmatter SM
Published figure using Phospho-Tau (Ser262) polyclonal antibody (Product # 44-750G) in Western Blot
Tue May 03 00:00:00 EDT 2022
Tau antibody 77G7 targeting microtubule binding domain suppresses proteopathic tau to seed tau aggregation.
CNS neuroscience & therapeutics
Li L,Miao J,Chu D,Jin N,Tung YC,Dai CL,Hu W,Gong CX,Iqbal K,Liu F
44-750G was used in Immunohistochemistry and Western Blotting to indicate that 77G7 can effectively suppress the seeding activity of AD O-tau and thus could be developed as a potential immunotherapeutic drug to inhibit the propagation of tau pathology in AD and related tauopathies.
Thu Dec 01 00:00:00 EST 2022
Tau antibody 77G7 targeting microtubule binding domain suppresses proteopathic tau to seed tau aggregation.
CNS neuroscience & therapeutics
Li L,Miao J,Chu D,Jin N,Tung YC,Dai CL,Hu W,Gong CX,Iqbal K,Liu F
44-750G was used in Immunohistochemistry and Western Blotting to indicate that 77G7 can effectively suppress the seeding activity of AD O-tau and thus could be developed as a potential immunotherapeutic drug to inhibit the propagation of tau pathology in AD and related tauopathies.
Thu Dec 01 00:00:00 EST 2022
Crry silencing alleviates Alzheimer's disease injury by regulating neuroinflammatory cytokines and the complement system.
Neural regeneration research
Zhu XC,Liu L,Dai WZ,Ma T
44-750G was used in Immunohistochemistry (Paraffin), Western Blot to suggest that Crry silencing in the P301S mouse model reduces tau protein phosphorylation by reducing the levels of neuroinflammation and complement components, thereby improving cognitive function.
Mon Aug 01 00:00:00 EDT 2022
Crry silencing alleviates Alzheimer's disease injury by regulating neuroinflammatory cytokines and the complement system.
Neural regeneration research
Zhu XC,Liu L,Dai WZ,Ma T
44-750G was used in Immunohistochemistry (Paraffin), Western Blot to suggest that Crry silencing in the P301S mouse model reduces tau protein phosphorylation by reducing the levels of neuroinflammation and complement components, thereby improving cognitive function.
Mon Aug 01 00:00:00 EDT 2022
Tau protein is differentially phosphorylated in young- and old-aged rats with experimentally induced hyperthyroidism.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience
Tan B,Babur E,Toy N,Günaydın B,Dursun N,Süer C
44-750G was used in Immunohistochemistry (Paraffin), Western Blot to study long-term potentiation (LTP) and accompanying phosphorylation of Tau protein in different residues in the hippocampus of young and old rats with experimentally induced hyperthyroidism.
Tue Nov 01 00:00:00 EDT 2022
Protein phosphatase 2A restrains DLK signaling to promote proper Drosophila synaptic development and mammalian cortical neuron survival.
Neurobiology of disease
Hayne M,DiAntonio A
44-750G was used in Western Blotting to demonstrate that inhibition of the DLK pathway is an essential function of Protein phosphatase 2A (PP2A) required for normal Drosophila synaptic terminal development and mammalian cortical neuron survival.
Tue Feb 01 00:00:00 EST 2022
Identification of a reciprocal negative feedback loop between tau-modifying proteins MARK2 kinase and CBP acetyltransferase.
The Journal of biological chemistry
Tabassum Z,Tseng JH,Isemann C,Tian X,Chen Y,Herring LE,Cohen TJ
44-750G was used in Immunoelectrophoresis to suggest that PTM profiles occur through the post-translational control of the master PTM remodeling enzymes themselves.
Wed Jun 01 00:00:00 EDT 2022
Urolithin A suppresses high glucose-induced neuronal amyloidogenesis by modulating TGM2-dependent ER-mitochondria contacts and calcium homeostasis.
Cell death and differentiation
Lee HJ,Jung YH,Choi GE,Kim JS,Chae CW,Lim JR,Kim SY,Yoon JH,Cho JH,Lee SJ,Han HJ
44-750G was used in Western Blot to investigate the effect of urolithin A on reducing amyloidogenesis by modulating mitochondrial calcium influx and mitochondrial ROS production in neuronal cells.
Fri Jan 01 00:00:00 EST 2021
PKR kinase directly regulates tau expression and Alzheimer's disease-related tau phosphorylation.
Brain pathology (Zurich, Switzerland)
Reimer L,Betzer C,Kofoed RH,Volbracht C,Fog K,Kurhade C,Nilsson E,Överby AK,Jensen PH
44-750G was used in Western Blot to indicate that PKR, independent of other kinases and upon acute brain inflammation, is capable of triggering pathological modulation of tau, which, in turn, might form the initial pathologic seed in several tauopathies such as Alzheimer's disease and Chronic traumatic encephalopathy where inflammation is severe.
Fri Jan 01 00:00:00 EST 2021
Pentoxifylline prevents epileptic seizure via modulating HMGB1/RAGE/TLR4 signalling pathway and improves memory in pentylenetetrazol kindling rats.
Clinical and experimental pharmacology & physiology
Badawi GA,Shokr MM,Zaki HF,Mohamed AF
44-750G was used in Immunohistochemistry (Paraffin), Western Blot to find that PTX or its combination with phenytoin represent a promising drug to inhibit the epilepsy progression via targeting the HMGB1/TLR4/RAGE signalling pathway.
Sun Aug 01 00:00:00 EDT 2021
Loganin substantially ameliorates molecular deficits, pathologies and cognitive impairment in a mouse model of Alzheimer's disease.
Aging
Nie L,He K,Xie F,Xiao S,Li S,Xu J,Zhang K,Yang C,Zhou L,Liu J,Zou L,Yang X
Published figure using Phospho-Tau (Ser262) polyclonal antibody (Product # 44-750G) in Immunohistochemistry
Sat Oct 23 00:00:00 EDT 2021
Sustained Hippocampal Synaptic Pathophysiology Following Single and Repeated Closed-Head Concussive Impacts.
Frontiers in cellular neuroscience
McDaid J,Briggs CA,Barrington NM,Peterson DA,Kozlowski DA,Stutzmann GE
Published figure using Phospho-Tau (Ser262) polyclonal antibody (Product # 44-750G) in Immunohistochemistry
Wed Apr 21 00:00:00 EDT 2021
Sustained Hippocampal Synaptic Pathophysiology Following Single and Repeated Closed-Head Concussive Impacts.
Frontiers in cellular neuroscience
McDaid J,Briggs CA,Barrington NM,Peterson DA,Kozlowski DA,Stutzmann GE
Published figure using Phospho-Tau (Ser262) polyclonal antibody (Product # 44-750G) in Immunohistochemistry
Wed Apr 21 00:00:00 EDT 2021
Mixed pathologies in pancreatic β cells from subjects with neurodegenerative diseases and their interaction with prion protein.
Acta neuropathologica communications
Martinez-Valbuena I,Valenti-Azcarate R,Amat-Villegas I,Marcilla I,Marti-Andres G,Caballero MC,Riverol M,Tuñon MT,Fraser PE,Luquin MR
44-750G was used in Immunohistochemistry to show that the involvement of amylin, pancreatic α-synuclein, Aβ, PrP and tau in the complex pathophysiology of type two diabetes and in the appearance of insulin resistance in Alzheimer's and Parkinson's disease.
Thu Apr 08 00:00:00 EDT 2021
Mixed pathologies in pancreatic β cells from subjects with neurodegenerative diseases and their interaction with prion protein.
Acta neuropathologica communications
Martinez-Valbuena I,Valenti-Azcarate R,Amat-Villegas I,Marcilla I,Marti-Andres G,Caballero MC,Riverol M,Tuñon MT,Fraser PE,Luquin MR
44-750G was used in Immunohistochemistry to show that the involvement of amylin, pancreatic α-synuclein, Aβ, PrP and tau in the complex pathophysiology of type two diabetes and in the appearance of insulin resistance in Alzheimer's and Parkinson's disease.
Thu Apr 08 00:00:00 EDT 2021
IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer's disease.
Cell reports
Brigas HC,Ribeiro M,Coelho JE,Gomes R,Gomez-Murcia V,Carvalho K,Faivre E,Costa-Pereira S,Darrigues J,de Almeida AA,Buée L,Dunot J,Marie H,Pousinha PA,Blum D,Silva-Santos B,Lopes LV,Ribot JC
44-750G was used in Western Blot to support the idea that cognition relies on a finely regulated balance of "inflammatory" cytokines derived from the meningeal immune system.
Tue Aug 31 00:00:00 EDT 2021
Brain-specific repression of AMPKα1 alleviates pathophysiology in Alzheimer's model mice.
The Journal of clinical investigation
Zimmermann HR,Yang W,Kasica NP,Zhou X,Wang X,Beckelman BC,Lee J,Furdui CM,Keene CD,Ma T
44-750G was used in Western Blotting to show that distinct disruption of hippocampal AMPKα isoform expression patterns in postmortem human Alzheimer's disease(AD) patients and AD model mice.
Wed Jul 01 00:00:00 EDT 2020
Melatonin directly binds and inhibits death-associated protein kinase 1 function in Alzheimer's disease.
Journal of pineal research
Chen D,Mei Y,Kim N,Lan G,Gan CL,Fan F,Zhang T,Xia Y,Wang L,Lin C,Ke F,Zhou XZ,Lu KP,Lee TH
44-750G was used in Western Blot to study melatonin as a critical regulator of death-associated protein kinase 1 levels and function, in patients with upregulated death-associated protein kinase 1 expression, implicated in the development of Alzheimer's disease.
Tue Sep 01 00:00:00 EDT 2020
Effects of Aerobic Exercise on Tau and Related Proteins in Rats with the Middle Cerebral Artery Occlusion.
International journal of molecular sciences
Mankhong S,Kim S,Moon S,Lee KH,Jeon HE,Hwang BH,Beak JW,Joa KL,Kang JH
44-750G was used in Western Blotting to evaluate the effects of aerobic exercise on the phosphorylation and acetylation of tau and the expressions of tau-related proteins, after middle cerebral artery occlusion (MCAO) stroke.
Fri Aug 14 00:00:00 EDT 2020
Effects of Aerobic Exercise on Tau and Related Proteins in Rats with the Middle Cerebral Artery Occlusion.
International journal of molecular sciences
Mankhong S,Kim S,Moon S,Lee KH,Jeon HE,Hwang BH,Beak JW,Joa KL,Kang JH
44-750G was used in Western Blotting to evaluate the effects of aerobic exercise on the phosphorylation and acetylation of tau and the expressions of tau-related proteins, after middle cerebral artery occlusion (MCAO) stroke.
Fri Aug 14 00:00:00 EDT 2020
Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization.
Scientific reports
Dominguez-Meijide A,Vasili E,König A,Cima-Omori MS,Ibáñez de Opakua A,Leonov A,Ryazanov S,Zweckstetter M,Griesinger C,Outeiro TF
44-750G was used in Western Blotting to assess the effects of different pharmacological interventions on the aggregation and internalization of tau and aSyn.
Thu Jul 30 00:00:00 EDT 2020
Truncation of Tau selectively facilitates its pathological activities.
The Journal of biological chemistry
Gu J,Xu W,Jin N,Li L,Zhou Y,Chu D,Gong CX,Iqbal K,Liu F
44-750G was used in Western Blotting to suggest that the first 150 aa and the last 50 aa protect Tau from pathological characteristics and that their deletions facilitate pathological activities.
Fri Oct 02 00:00:00 EDT 2020
Amylin as a potential link between type 2 diabetes and alzheimer disease.
Annals of neurology
Martinez-Valbuena I,Valenti-Azcarate R,Amat-Villegas I,Riverol M,Marcilla I,de Andrea CE,Sánchez-Arias JA,Del Mar Carmona-Abellan M,Marti G,Erro ME,Martínez-Vila E,Tuñon MT,Luquin MR
44-750G was used in Immunohistochemistry (Paraffin), Western Blot to assess ed whether tau and β-amyloid (Aβ) deposits might be present in pancreatic tissue of subjects with Alzheimer's disease, and whether amylin, an amyloidogenic protein deposited in the pancreas of T2DM patients, might accumulate in the brain of Alzheimer's disease patients.
Tue Oct 01 00:00:00 EDT 2019
Amylin as a potential link between type 2 diabetes and alzheimer disease.
Annals of neurology
Martinez-Valbuena I,Valenti-Azcarate R,Amat-Villegas I,Riverol M,Marcilla I,de Andrea CE,Sánchez-Arias JA,Del Mar Carmona-Abellan M,Marti G,Erro ME,Martínez-Vila E,Tuñon MT,Luquin MR
44-750G was used in Immunohistochemistry (Paraffin), Western Blot to assess ed whether tau and β-amyloid (Aβ) deposits might be present in pancreatic tissue of subjects with Alzheimer's disease, and whether amylin, an amyloidogenic protein deposited in the pancreas of T2DM patients, might accumulate in the brain of Alzheimer's disease patients.
Tue Oct 01 00:00:00 EDT 2019
Pathological Tau From Alzheimer's Brain Induces Site-Specific Hyperphosphorylation and SDS- and Reducing Agent-Resistant Aggregation of Tau in vivo.
Frontiers in aging neuroscience
Miao J,Shi R,Li L,Chen F,Zhou Y,Tung YC,Hu W,Gong CX,Iqbal K,Liu F
44-750G was used in Western Blotting to speculate that AD P-tau seeds hyperphosphorylated tau to form aggregates, which resist to the dephosphorylation by PP2A, resulting in hyperphosphorylation and pathology of tau.
Thu Oct 01 00:00:00 EDT 2020
Isozyme-Specific Role of SAD-A in Neuronal Migration During Development of Cerebral Cortex.
Cerebral cortex (New York, N.Y. : 1991)
Nakanishi K,Niida H,Tabata H,Ito T,Hori Y,Hattori M,Johmura Y,Yamada C,Ueda T,Takeuchi K,Yamada K,Nagata KI,Wakamatsu N,Kishi M,Pan YA,Ugawa S,Shimada S,Sanes JR,Higashi Y,Nakanishi M
44-750G was used in Western Blotting to reveal a nonredundant role for SAD-A in neuronal migration and differentiation in the cerebral cortex of mice.
Wed Aug 14 00:00:00 EDT 2019
α-lipoic acid attenuates spatial learning and memory impairment induced by hepatectomy.
Experimental and therapeutic medicine
Zhang Y,Lv YL,Si YN,Zhou J,Qian Y,Bao HG
Published figure using Phospho-Tau (Ser262) polyclonal antibody (Product # 44-750G) in Western Blot
Fri Mar 01 00:00:00 EST 2019
Caffeine Consumption During Pregnancy Accelerates the Development of Cognitive Deficits in Offspring in a Model of Tauopathy.
Frontiers in cellular neuroscience
Zappettini S,Faivre E,Ghestem A,Carrier S,Buée L,Blum D,Esclapez M,Bernard C
Published figure using Phospho-Tau (Ser262) polyclonal antibody (Product # 44-750G) in Western Blot
Wed Sep 30 00:00:00 EDT 2020
GSKIP-Mediated Anchoring Increases Phosphorylation of Tau by PKA but Not by GSK3beta via cAMP/PKA/GSKIP/GSK3/Tau Axis Signaling in Cerebrospinal Fluid and iPS Cells in Alzheimer Disease.
Journal of clinical medicine
Ko HJ,Chiou SJ,Wong YH,Wang YH,Lai Y,Chou CH,Wang C,Loh JK,Lieu AS,Cheng JT,Lin YT,Lu PJ,Fann MJ,Huang CF,Hong YR
Published figure using Phospho-Tau (Ser262) polyclonal antibody (Product # 44-750G) in Western Blot
Mon Oct 21 00:00:00 EDT 2019
The KLDpT activation loop motif is critical for MARK kinase activity.
PloS one
Sonntag T,Moresco JJ,Yates JR,Montminy M
44-750G was used in Western Blotting to show that, although MARKs and the closely related salt-inducible kinases phosphorylate substrates with consensus AMPK motifs comparably, MARKs are more potent in recognising variant ζXKXGSXXNΨ motifs on cellular tau.
Wed Mar 25 00:00:00 EDT 2020
Subacute to chronic Alzheimer-like alterations after controlled cortical impact in human tau transgenic mice.
Scientific reports
Zhang Y,Wu F,Iqbal K,Gong CX,Hu W,Liu F
44-750G was used in Western Blotting to characterise Alzheimer-like alterations behaviourally, biochemically and immunohistochemically 6 weeks and 7 months after unilateral mild-to-moderate controlled cortical impact in human tau transgenic mice.
Thu Mar 07 00:00:00 EST 2019
The Isoquinoline Alkaloid Dauricine Targets Multiple Molecular Pathways to Ameliorate Alzheimer-Like Pathological Changes In Vitro.
Oxidative medicine and cellular longevity
Liu P,Chen X,Zhou H,Wang L,Zhang Z,Ren X,Zhu F,Guo Y,Huang X,Liu J,Spencer PS,Yang X
Published figure using Phospho-Tau (Ser262) polyclonal antibody (Product # 44-750G) in Western Blot
Mon Oct 22 00:00:00 EDT 2018
Isoflurane anesthesia in aged mice and effects of A1 adenosine receptors on cognitive impairment.
CNS neuroscience & therapeutics
Zuo CL,Wang CM,Liu J,Shen T,Zhou JP,Hao XR,Pan YZ,Liu HC,Lian QQ,Lin H
Published figure using Phospho-Tau (Ser262) polyclonal antibody (Product # 44-750G) in Western Blot
Thu Mar 01 00:00:00 EST 2018
Involvement of Activation of Asparaginyl Endopeptidase in Tau Hyperphosphorylation in Repetitive Mild Traumatic Brain Injury.
Journal of Alzheimer's disease : JAD
Hu W,Tung YC,Zhang Y,Liu F,Iqbal K
44-750G was used in Western Blotting to test the effect of repetitive mild traumatic brain injury on tau hyperphosphorylation, in triple-transgenic mouse model of Alzheimer's disease.
Mon Jul 15 00:00:00 EDT 2019
Involvement of Activation of Asparaginyl Endopeptidase in Tau Hyperphosphorylation in Repetitive Mild Traumatic Brain Injury.
Journal of Alzheimer's disease : JAD
Hu W,Tung YC,Zhang Y,Liu F,Iqbal K
44-750G was used in Western Blotting to test the effect of repetitive mild traumatic brain injury on tau hyperphosphorylation, in triple-transgenic mouse model of Alzheimer's disease.
Mon Jul 15 00:00:00 EDT 2019
Rac1 activation links tau hyperphosphorylation and Aβ dysmetabolism in Alzheimer's disease.
Acta neuropathologica communications
Borin M,Saraceno C,Catania M,Lorenzetto E,Pontelli V,Paterlini A,Fostinelli S,Avesani A,Di Fede G,Zanusso G,Benussi L,Binetti G,Zorzan S,Ghidoni R,Buffelli M,Bolognin S
44-750G was used in Immunocytochemistry-immunoflourescence to show that Rac1 levels decreased in the frontal cortex of Alzheimer's disease patients compared to non-demented controls.
Fri Jul 13 00:00:00 EDT 2018
Tau deletion promotes brain insulin resistance.
The Journal of experimental medicine
Marciniak E,Leboucher A,Caron E,Ahmed T,Tailleux A,Dumont J,Issad T,Gerhardt E,Pagesy P,Vileno M,Bournonville C,Hamdane M,Bantubungi K,Lancel S,Demeyer D,Eddarkaoui S,Vallez E,Vieau D,Humez S,Faivre E,Grenier-Boley B,Outeiro TF,Staels B,Amouyel P,Balschun D,Buee L,Blum D
44-750G was used in Western Blotting to find that tau deletion leads to an impaired hippocampal response to insulin, caused by altered IRS-1 and PTEN activity.
Mon Aug 07 00:00:00 EDT 2017
Stabilization of dynamic microtubules by mDia1 drives Tau-dependent Aβ1-42 synaptotoxicity.
The Journal of cell biology
Qu X,Yuan FN,Corona C,Pasini S,Pero ME,Gundersen GG,Shelanski ML,Bartolini F
Published figure using Phospho-Tau (Ser262) polyclonal antibody (Product # 44-750G) in Western Blot
Mon Oct 02 00:00:00 EDT 2017
A Dual Pathogenic Mechanism Links Tau Acetylation to Sporadic Tauopathy.
Scientific reports
Trzeciakiewicz H,Tseng JH,Wander CM,Madden V,Tripathy A,Yuan CX,Cohen TJ
44750G was used in western blot to study the mechanisms of pathogenesis via tau acetylation in Alzheimer's disease
Mon Mar 13 00:00:00 EDT 2017
The Deacetylase HDAC6 Mediates Endogenous Neuritic Tau Pathology.
Cell reports
Tseng JH,Xie L,Song S,Xie Y,Allen L,Ajit D,Hong JS,Chen X,Meeker RB,Cohen TJ
Published figure using Phospho-Tau (Ser262) polyclonal antibody (Product # 44-750G) in Immunocytochemistry
Tue Aug 29 00:00:00 EDT 2017
Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma.
BMC neuroscience
O'Hare Doig RL,Chiha W,Giacci MK,Yates NJ,Bartlett CA,Smith NM,Hodgetts SI,Harvey AR,Fitzgerald M
44-750G was used in Immunohistochemistry to determine how flux through specific ion channels contributes to the various pathologies, using partial optic nerve transection in adult female rats to model secondary degeneration following neurotrauma.
Mon Aug 14 00:00:00 EDT 2017
Elucidation of Dietary Polyphenolics as Potential Inhibitor of Microtubule Affinity Regulating Kinase 4: In silico and In vitro Studies.
Scientific reports
Khan P,Rahman S,Queen A,Manzoor S,Naz F,Hasan GM,Luqman S,Kim J,Islam A,Ahmad F,Hassan MI
44-750G was used in Flow cytometry to evaluate different natural dietary polyphenolics as microtubule affinity regulating kinase 4 inhibitors.
Fri Aug 25 00:00:00 EDT 2017
Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein.
Aging cell
Manassero G,Guglielmotto M,Zamfir R,Borghi R,Colombo L,Salmona M,Perry G,Odetti P,Arancio O,Tamagno E,Tabaton M
44-750G was used in western blot elucidate the mechanistic relationship between amyloid beta1-42 and Tau
Sat Oct 01 00:00:00 EDT 2016
Neutral Sphingomyelinase-2 Deficiency Ameliorates Alzheimer's Disease Pathology and Improves Cognition in the 5XFAD Mouse.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Dinkins MB,Enasko J,Hernandez C,Wang G,Kong J,Helwa I,Liu Y,Terry AV,Bieberich E
44750G was used in western blot to report that reduced exosome secretion due to nSMase2 loss improves pathology and cognition in a mouse model of Alzheimer's disease
Wed Aug 17 00:00:00 EDT 2016
Tau hyperphosphorylation in synaptosomes and neuroinflammation are associated with canine cognitive impairment.
The Journal of comparative neurology
Smolek T,Madari A,Farbakova J,Kandrac O,Jadhav S,Cente M,Brezovakova V,Novak M,Zilka N
44-750G was used in immunohistochemistry - paraffin section and western blot to study canine cognitive impairment syndrome.
Tue Mar 01 00:00:00 EST 2016
Tau hyperphosphorylation in synaptosomes and neuroinflammation are associated with canine cognitive impairment.
The Journal of comparative neurology
Smolek T,Madari A,Farbakova J,Kandrac O,Jadhav S,Cente M,Brezovakova V,Novak M,Zilka N
44-750G was used in immunohistochemistry - paraffin section and western blot to study canine cognitive impairment syndrome.
Tue Mar 01 00:00:00 EST 2016
Tau hyperphosphorylation in synaptosomes and neuroinflammation are associated with canine cognitive impairment.
The Journal of comparative neurology
Smolek T,Madari A,Farbakova J,Kandrac O,Jadhav S,Cente M,Brezovakova V,Novak M,Zilka N
44-750G was used in immunohistochemistry - paraffin section and western blot to study canine cognitive impairment syndrome.
Tue Mar 01 00:00:00 EST 2016
Attenuation of synaptic toxicity and MARK4/PAR1-mediated Tau phosphorylation by methylene blue for Alzheimer's disease treatment.
Scientific reports
Sun W,Lee S,Huang X,Liu S,Inayathullah M,Kim KM,Tang H,Ashford JW,Rajadas J
Published figure using Phospho-Tau (Ser262) polyclonal antibody (Product # 44-750G) in Western Blot
Thu Oct 06 00:00:00 EDT 2016
Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain.
Nature communications
Takeda S,Wegmann S,Cho H,DeVos SL,Commins C,Roe AD,Nicholls SB,Carlson GA,Pitstick R,Nobuhara CK,Costantino I,Frosch MP,Müller DJ,Irimia D,Hyman BT
44-750G was used in western blot to research Alzheimer's disease brain and neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau
Tue Oct 13 00:00:00 EDT 2015
Tau pathogenesis is promoted by Aβ1-42 but not Aβ1-40.
Molecular neurodegeneration
Hu X,Li X,Zhao M,Gottesdiener A,Luo W,Paul S
Published figure using Phospho-Tau (Ser262) polyclonal antibody (Product # 44-750G) in Western Blot
Sun Nov 23 00:00:00 EST 2014
Tau pathogenesis is promoted by Aβ1-42 but not Aβ1-40.
Molecular neurodegeneration
Hu X,Li X,Zhao M,Gottesdiener A,Luo W,Paul S
Published figure using Phospho-Tau (Ser262) polyclonal antibody (Product # 44-750G) in Western Blot
Sun Nov 23 00:00:00 EST 2014
Specificity of anti-tau antibodies when analyzing mice models of Alzheimer's disease: problems and solutions.
PloS one
Petry FR,Pelletier J,Bretteville A,Morin F,Calon F,Hébert SS,Whittington RA,Planel E
44-750G was used in western blot to study the specificity of a panel of commonly used anti-tau antibodies and issues likely to be encounted in Western blot experiments using material from murine Alzheimer's disease models
Mon Dec 22 00:00:00 EST 2014
Age-dependent effects of A53T alpha-synuclein on behavior and dopaminergic function.
PloS one
Oaks AW,Frankfurt M,Finkelstein DI,Sidhu A
44-750G was used in western blot to use a mouse model to examine motor activity, anxiety-like, and depressive-like behaviors both before and after the onset of Parkinson's disease
Mon Sep 16 00:00:00 EDT 2013
Microtubule-associated protein tau in bovine retinal photoreceptor rod outer segments: comparison with brain tau.
Biochimica et biophysica acta
Yamazaki A,Nishizawa Y,Matsuura I,Hayashi F,Usukura J,Bondarenko VA
44-750G was used in western blot to characterize tau in the rod outer segment of bovine retinal photoreceptors.
Tue Oct 01 00:00:00 EDT 2013
An experimental rat model of sporadic Alzheimer's disease and rescue of cognitive impairment with a neurotrophic peptide.
Acta neuropathologica
Bolognin S,Blanchard J,Wang X,Basurto-Islas G,Tung YC,Kohlbrenner E,Grundke-Iqbal I,Iqbal K
44-750G was used in immunohistochemistry - free floating and western blot to report that expression of the N-terminal I2NTF and C-terminal I2CTF halves of I2PP2A in rat brain reproduced key features of Alzheimer's disease
Sun Jan 01 00:00:00 EST 2012
Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo.
Autophagy
Congdon EE,Wu JW,Myeku N,Figueroa YH,Herman M,Marinec PS,Gestwicki JE,Dickey CA,Yu WH,Duff KE
44-750G was used in western blot to report that autophagy is a mechanism by which methylene blue reduces tau levels.
Sun Apr 01 00:00:00 EDT 2012
Asp664 cleavage of amyloid precursor protein induces tau phosphorylation by decreasing protein phosphatase 2A activity.
Journal of neurochemistry
Park SS,Jung HJ,Kim YJ,Park TK,Kim C,Choi H,Mook-Jung IH,Koo EH,Park SA
Published figure using Phospho-Tau (Ser262) polyclonal antibody (Product # 44-750G) in Immunocytochemistry
Sat Dec 01 00:00:00 EST 2012
Asp664 cleavage of amyloid precursor protein induces tau phosphorylation by decreasing protein phosphatase 2A activity.
Journal of neurochemistry
Park SS,Jung HJ,Kim YJ,Park TK,Kim C,Choi H,Mook-Jung IH,Koo EH,Park SA
Published figure using Phospho-Tau (Ser262) polyclonal antibody (Product # 44-750G) in Immunocytochemistry
Sat Dec 01 00:00:00 EST 2012
Transgenic mouse and cell culture models demonstrate a lack of mechanistic connection between endoplasmic reticulum stress and tau dysfunction.
Journal of neuroscience research
Spatara ML,Robinson AS
44-750G was used in western blot to elucidate the between tau aggregation and the unfolded protein response in neurodegenerative disorders
Thu Jul 01 00:00:00 EDT 2010
Developmental regulation of tau phosphorylation, tau kinases, and tau phosphatases.
Journal of neurochemistry
Yu Y,Run X,Liang Z,Li Y,Liu F,Liu Y,Iqbal K,Grundke-Iqbal I,Gong CX
Sun Mar 01 00:00:00 EST 2009
Developmental regulation of tau phosphorylation, tau kinases, and tau phosphatases.
Journal of neurochemistry
Yu Y,Run X,Liang Z,Li Y,Liu F,Liu Y,Iqbal K,Grundke-Iqbal I,Gong CX
Sun Mar 01 00:00:00 EST 2009
Interleukin-18 increases expression of kinases involved in tau phosphorylation in SH-SY5Y neuroblastoma cells.
Journal of neuroimmunology
Ojala JO,Sutinen EM,Salminen A,Pirttilä T
44-750G was used in western blot to suggest that IL-18 over-expression induces hyperphosphorylation of tau and induces cell cycle activators
Mon Dec 15 00:00:00 EST 2008
Kinase activities increase during the development of tauopathy in htau mice.
Journal of neurochemistry
Kelleher I,Garwood C,Hanger DP,Anderton BH,Noble W
Sat Dec 01 00:00:00 EST 2007
Suppression of tubulin polymerization by the LKB1-microtubule-associated protein/microtubule affinity-regulating kinase signaling.
The Journal of biological chemistry
Kojima Y,Miyoshi H,Clevers HC,Oshima M,Aoki M,Taketo MM
44-750G was used in Western Blotting to study the involvement of LKB1 in the regulation of microtubule dynamics through the activation of microtubule-associated protein/microtubule affinity-regulating kinases.
Fri Aug 10 00:00:00 EDT 2007
Increased tau phosphorylation on mitogen-activated protein kinase consensus sites and cognitive decline in transgenic models for Alzheimer's disease and FTDP-17: evidence for distinct molecular processes underlying tau abnormalities.
Molecular and cellular biology
Lambourne SL,Sellers LA,Bush TG,Choudhury SK,Emson PC,Suh YH,Wilkinson LS
Sat Jan 01 00:00:00 EST 2005
Pseudophosphorylation of tau protein alters its ability for self-aggregation.
Journal of neurochemistry
Haase C,Stieler JT,Arendt T,Holzer M
Mon Mar 01 00:00:00 EST 2004
Pseudophosphorylation of tau protein alters its ability for self-aggregation.
Journal of neurochemistry
Haase C,Stieler JT,Arendt T,Holzer M
Mon Mar 01 00:00:00 EST 2004
