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5-mCpA Antibody (61783) in DB
5-meCpA Antibody Specifity Dot blot analysis was used to confirm the specificity of 5-meCpA antibody for the 5-meCpA dinucleotide. Single-stranded DNA oligonucleotides (amount of oligo in nanograms listed on the left side of the blot) were spotted on to a positively charged nylon membrane and blotted with 5-meCpA (1 µg/ml dilution).
Product Details
61783
Product Specifications
Species Reactivity
Chemical
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2C8H8A6
Immunogen
This antibody was raised against 5-methyl-cytosine-adenosine di-nucleoside conjugated to KLH and recognized 5-mCpA.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.5, with 30% glycerol
Contains
0.035% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2793764
Target Information
Methylation of CpA (mCpA) generates a DNA pyrimidine with a methyl group in the 5-carbon position. DNA methylation is usually catalyzed by DNA methyltransferases generally at CpG dinucleotide positions, though non-CpG methylation has also been reported at CpA and CpT sites. DNA methylation is known to repress gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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