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Proteintech
Apolipoprotein AI Monoclonal Antibody (1C9G5)
Product Details
66206-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
1C9G5
Immunogen
Apolipoprotein AI Fusion Protein Ag21920 (19-267 aa encoded by BC005380)
Conjugate
Form
Liquid
Concentration
1.07 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody was generated against the C-terminal region of human ApoA1.
Immunogen sequence: RHFWQQDEP PQSPWDRVKD LATVYVDVLK DSGRDYVSQF EGSALGKQLN LKLLDNWDSV TSTFSKLREQ LGPVTQEFWD NLEKETEGLR QEMSKDLEEV KAKVQPYLDD FQKKWQEEME LYRQKVEPLR AELQEGARQK LHELQEKLSP LGEEMRDRAR AHVDALRTHL APYSDELRQR LAARLEALKE NGGARLAEYH AKATEHLSTL SEKAKPALED LRQGLLPVLE SFKVSFLSAL EEYTKKLNTQ (19-267 aa encoded by BC005380)
Target Information
Apolipoprotein A-1 (apo A-1) in human plasma is a major protein component of high density lipoprotein (HDL). The molecular mass is 24 kDa. Apo A-1 is a cofactor for enzymes involved in the normal turnover of cholesterol and is produced in the liver. Plasma concentration is 270-380 mg/100 mL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 1-Sep; 2-Sep; Apo a; apo A-1; APO A1; APO I; Apo-AI; ApoAI; Apolipoprotein; Apolipoprotein A-I; Apolipoprotein A1; Apolipoprotein AI; MGC102525; MGC117399; MGC124929; Udpgt; Ugt1; Ugt1a7
Gene Aliases: Alp-1; apo(a); apo-AI; Apoa-1; apoA-I; APOA1; Brp-14; Ltw-1; Lvtw-1; Sep-1; Sep-2; Sep2
UniProt ID: (Human) P02647, (Mouse) Q00623
Entrez Gene ID: (Human) 335, (Mouse) 11806
beta-amyloid binding
protein binding
phospholipid binding
phospholipid transporter activity
high-density lipoprotein particle binding
cholesterol binding
cholesterol transporter activity
enzyme binding
phosphatidylcholine binding
apolipoprotein receptor binding
apolipoprotein A-I receptor binding
identical protein binding
chemorepellent activity
lipase inhibitor activity
phosphatidylcholine-sterol O-acyltransferase activator activity
high-density lipoprotein particle receptor binding
lipid transporter activity
lipid binding
lipoprotein particle binding
apolipoprotein
retinoid metabolic process
regulation of protein phosphorylation
endothelial cell proliferation
platelet degranulation
negative regulation of cytokine secretion involved in immune response
phospholipid metabolic process
phosphatidylcholine biosynthetic process
cholesterol biosynthetic process
receptor-mediated endocytosis
transforming growth factor beta receptor signaling pathway
G-protein coupled receptor signaling pathway
integrin-mediated signaling pathway
response to nutrient
cholesterol metabolic process
glucocorticoid metabolic process
negative regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of cholesterol esterification
positive regulation of triglyceride catabolic process
negative regulation of very-low-density lipoprotein particle remodeling
peripheral nervous system axon regeneration
protein oxidation
peptidyl-methionine modification
triglyceride catabolic process
lipid storage
regulation of intestinal cholesterol absorption
cholesterol transport
adrenal gland development
organ regeneration
neuron projection regeneration
regulation of Cdc42 protein signal transduction
cholesterol efflux
phospholipid efflux
negative regulation of heterotypic cell-cell adhesion
high-density lipoprotein particle remodeling
high-density lipoprotein particle assembly
high-density lipoprotein particle clearance
positive regulation of Rho protein signal transduction
lipoprotein metabolic process
lipoprotein biosynthetic process
response to drug
cholesterol homeostasis
blood vessel endothelial cell migration
response to estrogen
reverse cholesterol transport
cellular protein metabolic process
positive regulation of fatty acid biosynthetic process
negative regulation of interleukin-1 beta secretion
negative regulation of inflammatory response
protein stabilization
negative chemotaxis
positive regulation of lipoprotein lipase activity
vitamin transport
positive regulation of hydrolase activity
positive regulation of stress fiber assembly
transmembrane transport
phospholipid homeostasis
negative regulation of lipase activity
negative regulation of cell adhesion molecule production
negative regulation of response to cytokine stimulus
triglyceride homeostasis
ERK1 and ERK2 cascade
cholesterol import
positive regulation of substrate adhesion-dependent cell spreading
lipid metabolic process
transport
lipid transport
protein localization
steroid metabolic process
phospholipid transport
axon regeneration
very-low-density lipoprotein particle remodeling
phosphatidylcholine metabolic process
negative regulation of hydrolase activity
positive regulation of transferase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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