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Product Details
66226-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Not Applicable
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1D8B8
Immunogen
HPSE Fusion Protein Ag10067 (159-543 aa encoded by BC051321)
Conjugate
Form
Liquid
Concentration
2.08 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: KFKNSTYSR SSVDVLYTFA NCSGLDLIFG LNALLRTADL QWNSSNAQLL LDYCSSKGYN ISWELGNEPN SFLKKADIFI NGSQLGEDFI QLHKLLRKST FKNAKLYGPD VGQPRRKTAK MLKSFLKAGG EVIDSVTWHH YYLNGRTATR EDFLNPDVLD IFISSVQKVF QVVESTRPGK KVWLGETSSA YGGGAPLLSD TFAAGFMWLD KLGLSARMGI EVVMRQVFFG AGNYHLVDEN FDPLPDYWLS LLFKKLVGTK VLMASVQGSK RRKLRVYLHC TNTDNPRYKE GDLTLYAINL HNVTKYLRLP YPFSNKQVDK YLLRPLGPHG LLSKSVQLNG LTLKMVDDQT LPPLMEKPLR PGSSLGLPAF SYSFFVIRNA KVAACI (159-543 aa encoded by BC051321)
Target Information
Stem cells offer a therapeutic promise for many diseases. In the case of diabetes, stem cells offer the promise that beta cells may be generated ex vivo for the possible transplantation and cure of Type I diabetes (Couri CE, et al. ). For this to happen, stem cells will need to be isolated and expanded, they will need to be differentiated toward the beta cell lineage, and the differentiated cell progeny used for transplantation may need to be isolated from complex cell mixtures following differentiation. Appropriate markers targeting cell surface molecules on developing and mature pancreatic cells will be required for such research.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Endo-glucoronidase; Heparanase; Heparanase-1; Hpa1
Gene Aliases: HEP; HPA; HPA1; HPR1; HPSE; HPSE1; HSE1
UniProt ID: (Human) Q9Y251
Entrez Gene ID: (Human) 10855
carbohydrate metabolic process
glycosaminoglycan catabolic process
proteoglycan metabolic process
cell-matrix adhesion
positive regulation of vascular endothelial growth factor production
positive regulation of blood coagulation
extracellular matrix organization
heparan sulfate proteoglycan catabolic process
positive regulation of osteoblast proliferation
regulation of hair follicle development
positive regulation of hair follicle development
positive regulation of protein kinase B signaling
angiogenesis involved in wound healing
vascular wound healing
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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