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MPG functions in the hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3' end of the Mid1 gene, localized 68 kb upstream the humanzeta globin gene on 16p; 3-alkyladenine DNA glycosylase; 3-methyladenine DNA glycosidase; ADPG; CRA36.1 (3-methyl-adenine DNA glycosylase); DNA-3-methyladenine glycosylase; N-methylpurine-DNA glycocylase; N-methylpurine-DNA glycosylase; N-methylpurine-DNA glycosylase, MPG; proliferation-inducing protein 11; proliferation-inducing protein 16
Gene Aliases: AAG; ADPG; ANPG; APNG; CRA36.1; MDG; MID1; MPG; PIG11; PIG16
UniProt ID: (Human) Q13770
Entrez Gene ID: (Human) 4350, (Rat) 24561
Molecular Function:
DNA metabolism protein
DNA glycosylase
nucleic acid metabolism protein
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