Product References
A novel NEDD4L-TXNIP-CHOP axis in the pathogenesis of nonalcoholic steatohepatitis.
Theranostics
Guo Q,Xin M,Lu Q,Feng D,Yang V,Peng LF,Whelan KA,Hu W,Wu S,Yang X,Wang H,Rothberg BS,Gamero AM,Gerhard GS,Gao B,Yang L
MA1-135 was used in Western Blotting to reveal a pathogenic role of hepatic TXNIP in NASH and identified a novel NEDD4L-TXNIP-CHOP axis in the pathogenesis of NASH.
Wed May 10 00:00:00 EDT 2023
Svep1 is a binding ligand of Tie1 and affects specific aspects of facial lymphatic development in a Vegfc-independent manner.
eLife
Hußmann M,Schulte D,Weischer S,Carlantoni C,Nakajima H,Mochizuki N,Stainier DYR,Zobel T,Koch M,Schulte-Merker S
MA1-135 was used in Western Blotting to uncover an essential role for the secreted protein Svep1 and the transmembrane receptor Tie1 during the development of subpopulations of the zebrafish facial lymphatic network.
Tue Apr 25 00:00:00 EDT 2023
Anti-COX-2 autoantibody is a novel biomarker of immune aplastic anemia.
Leukemia
Kelkka T,Tyster M,Lundgren S,Feng X,Kerr C,Hosokawa K,Huuhtanen J,Keränen M,Patel B,Kawakami T,Maeda Y,Nieminen O,Kasanen T,Aronen P,Yadav B,Rajala H,Nakazawa H,Jaatinen T,Hellström-Lindberg E,Ogawa S,Ishida F,Nishikawa H,Nakao S,Maciejewski J,Young NS,Mustjoki S
MA1-135 was used in DELFIA to suggest that aCOX-2 Ab defines a distinct subgroup of IAA and may serve as a valuable disease biomarker.
Thu Sep 01 00:00:00 EDT 2022
Virus-like particles displaying conserved toxin epitopes stimulate polyspecific, murine antibody responses capable of snake venom recognition.
Scientific reports
Menzies SK,Dawson CA,Crittenden E,Edge RJ,Hall SR,Alsolaiss J,Wilkinson MC,Casewell NR,Harrison RA,Ainsworth S
MA1-135 was used in Western Blotting to demonstrate proof-of-principle that virus like particles engineered to display conserved toxin linear epitopes can elicit specific antibody responses in mice which are able to recognise a geographically broad range of elapid venoms.
Tue Jul 05 00:00:00 EDT 2022
Bassoon contributes to tau-seed propagation and neurotoxicity.
Nature neuroscience
Martinez P,Patel H,You Y,Jury N,Perkins A,Lee-Gosselin A,Taylor X,You Y,Viana Di Prisco G,Huang X,Dutta S,Wijeratne AB,Redding-Ochoa J,Shahid SS,Codocedo JF,Min S,Landreth GE,Mosley AL,Wu YC,McKinzie DL,Rochet JC,Zhang J,Atwood BK,Troncoso J,Lasagna-Reeves CA
MA1-135 was used in Immunohistochemistry (Paraffin) to improve the understanding of how tau seeds can be stabilized by interactors such as BSN.
Thu Dec 01 00:00:00 EST 2022
Fast clearance of platelets in a commonly used mouse model for GPIbα is impeded by an anti-GPIbβ antibody derivative.
Journal of thrombosis and haemostasis : JTH
Chen W,Wilson MS,Wang Y,Bergmeier W,Lanza F,Li R
MA1-135 was used in ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot, Flow Cytometry to provide the key evidence supporting the causative link of Trigger sequence exposure to accelerated platelet clearance, and suggest that a RAM.1 derivative may be therapeutically developed to treat GPIb-IX-mediated thrombocytopenia.
Wed Jun 01 00:00:00 EDT 2022
MeV-Stealth: A CD46-specific oncolytic measles virus resistant to neutralization by measles-immune human serum.
PLoS pathogens
Muñoz-Alía MÁ,Nace RA,Tischer A,Zhang L,Bah ES,Auton M,Russell SJ
Published figure using 6x-His Tag monoclonal antibody (Product # MA1-135) in ELISA
Mon Feb 01 00:00:00 EST 2021
Plxdc family members are novel receptors for the rhesus monkey rhadinovirus (RRV).
PLoS pathogens
Großkopf AK,Schlagowski S,Fricke T,Ensser A,Desrosiers RC,Hahn AS
MA1-135 was used in an ELISA assay to dentify additional cellular receptors for RRV by affinity enrichment and mass spectrometry.
Mon Mar 01 00:00:00 EST 2021
ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import.
Human molecular genetics
Lin BC,Phung TH,Higgins NR,Greenslade JE,Prado MA,Finley D,Karbowski M,Polster BM,Monteiro MJ
MA1-135 was used in Immunocytochemistry-immunoflourescence to indicate a potential key pathogenic disturbance in mitochondrial health caused by UBQLN2 mutations.
Thu Jun 17 00:00:00 EDT 2021
Leishmania donovani Secretory Mevalonate Kinase Regulates Host Immune Response and Facilitates Phagocytosis.
Frontiers in cellular and infection microbiology
Bamra T,Shafi T,Das S,Kumar M,Dikhit MR,Kumar A,Kumar A,Abhishek K,Pandey K,Sen A,Das P
Published figure using 6x-His Tag monoclonal antibody (Product # MA1-135) in Western Blot
Mon Jul 05 00:00:00 EDT 2021
Characterization of Phosphopantetheinyl Hydrolase from Mycobacterium tuberculosis.
Microbiology spectrum
Pandey S,Singh A,Yang G,d'Andrea FB,Jiang X,Hartman TE,Mosior JW,Bourland R,Gold B,Roberts J,Geiger A,Tang S,Rhee K,Ouerfelli O,Sacchettini JC,Nathan CF,Burns-Huang K
Published figure using 6x-His Tag monoclonal antibody (Product # MA1-135) in Western Blot
Sun Oct 31 00:00:00 EDT 2021
Analysis of the DNA-binding properties of Alx1, an evolutionarily conserved regulator of skeletogenesis in echinoderms.
The Journal of biological chemistry
Guerrero-Santoro J,Khor JM,Açıkbaş AH,Jaynes JB,Ettensohn CA
MA1-135 was used in Western Blot to show that the D2 domain influences the DNA-binding properties of Alx1 in vitro, suggesting that the exonization of this motif may have facilitated the acquisition of new transcriptional targets and consequently a novel developmental function.
Thu Jul 01 00:00:00 EDT 2021
Analysis of the DNA-binding properties of Alx1, an evolutionarily conserved regulator of skeletogenesis in echinoderms.
The Journal of biological chemistry
Guerrero-Santoro J,Khor JM,Açıkbaş AH,Jaynes JB,Ettensohn CA
MA1-135 was used in Western Blot to show that the D2 domain influences the DNA-binding properties of Alx1 in vitro, suggesting that the exonization of this motif may have facilitated the acquisition of new transcriptional targets and consequently a novel developmental function.
Thu Jul 01 00:00:00 EDT 2021
The BRCT domains of ECT2 have distinct functions during cytokinesis.
Cell reports
Schneid S,Wolff F,Buchner K,Bertram N,Baygün S,Barbosa P,Mangal S,Zanin E
MA1-135 was used in Western Blot to provide detailed mechanistic insights into how ECT2 activity is regulated and how that regulation ensures, together with other signaling pathways, successful cell division.
Tue Mar 02 00:00:00 EST 2021
UBE2S promotes cell chemoresistance through PTEN-AKT signaling in hepatocellular carcinoma.
Cell death discovery
Gui L,Zhang S,Xu Y,Zhang H,Zhu Y,Kong L
MA1-135 was used in Immunoprecipitation to show ubiquitin-conjugating enzyme E2S (UBE2S) upregulation is relevant with large tumor size, recurrence, and advanced TNM stage, serving as an independent risk factor of overall survival and disease-free survival for hepatocellular cancer patients.
Tue Nov 16 00:00:00 EST 2021
A conserved and seemingly redundant Escherichia coli biotin biosynthesis gene expressed only during anaerobic growth.
Molecular microbiology
Song X,Cronan JE
MA1-135 was used in Western Blotting to report that YnfK is a functional DTBS, although an enzyme of poor activity that is poorly expressed.
Mon Nov 01 00:00:00 EDT 2021
CRK2 and C-terminal Phosphorylation of NADPH Oxidase RBOHD Regulate Reactive Oxygen Species Production in Arabidopsis.
The Plant cell
Kimura S,Hunter K,Vaahtera L,Tran HC,Citterico M,Vaattovaara A,Rokka A,Stolze SC,Harzen A,Meißner L,Wilkens MMT,Hamann T,Toyota M,Nakagami H,Wrzaczek M
MA1-135 was used in western blotting to determine that reactive oxygen species production in Arabidopsis is regulated by CRK2 and the phosphorylation of the C-terminal region of NADPH oxidase.
Wed Apr 01 00:00:00 EDT 2020
Phospholipase pPLAIIIα Increases Germination Rate and Resistance to Turnip Crinkle Virus when Overexpressed.
Plant physiology
Jang JH,Nguyen NQ,Légeret B,Beisson F,Kim YJ,Sim HJ,Lee OR
MA1-135 was used in Western Blotting to provide new insights into the pathways downstream of pPLAIIIα.
Sun Nov 01 00:00:00 EDT 2020
Hepatitis Delta Virus histone mimicry drives the recruitment of chromatin remodelers for viral RNA replication.
Nature communications
Abeywickrama-Samarakoon N,Cortay JC,Sureau C,Müller S,Alfaiate D,Guerrieri F,Chaikuad A,Schröder M,Merle P,Levrero M,Dény P
Published figure using 6x-His Tag monoclonal antibody (Product # MA1-135) in Western Blot
Tue Jan 21 00:00:00 EST 2020
Cross-kingdom mimicry of the receptor signaling and leukocyte recruitment activity of a human cytokine by its plant orthologs.
The Journal of biological chemistry
Sinitski D,Gruner K,Brandhofer M,Kontos C,Winkler P,Reinstädler A,Bourilhon P,Xiao Z,Cool R,Kapurniotu A,Dekker FJ,Panstruga R,Bernhagen J
MA1-135 was used in Western Blotting to characterize three MIF orthologs (termed MIF/d-dopachrome tautomerase-like proteins or MDLs) of the model plant Arabidopsis thaliana Recombinant Arabidopsis MDLs (AtMDLs).
Fri Jan 17 00:00:00 EST 2020
A Direct Podocalyxin-Dynamin-2 Interaction Regulates Cytoskeletal Dynamics to Promote Migration and Metastasis in Pancreatic Cancer Cells.
Cancer research
Wong BS,Shea DJ,Mistriotis P,Tuntithavornwat S,Law RA,Bieber JM,Zheng L,Konstantopoulos K
MA1-135 was used in Western Blotting to investigate the role of podocalyxin in migration and metastasis of pancreatic adenocarcinomas using SW1990 and Pa03c as cell models.
Sat Jun 01 00:00:00 EDT 2019
Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.
Nature communications
Sigoillot M,Overtus M,Grodecka M,Scholl D,Garcia-Pino A,Laeremans T,He L,Pardon E,Hildebrandt E,Urbatsch I,Steyaert J,Riordan JR,Govaerts C
Published figure using 6x-His Tag monoclonal antibody (Product # MA1-135) in ELISA
Fri Jun 14 00:00:00 EDT 2019
Phylogenetically Defined Isoforms of Listeria monocytogenes Invasion Factor InlB Differently Activate Intracellular Signaling Pathways and Interact with the Receptor gC1q-R.
International journal of molecular sciences
Chalenko Y,Kalinin E,Marchenkov V,Sysolyatina E,Surin A,Sobyanin K,Ermolaeva S
Published figure using 6x-His Tag monoclonal antibody (Product # MA1-135) in ELISA
Sat Aug 24 00:00:00 EDT 2019
Integrin alpha11 is an Osteolectin receptor and is required for the maintenance of adult skeletal bone mass.
eLife
Shen B,Vardy K,Hughes P,Tasdogan A,Zhao Z,Yue R,Crane GM,Morrison SJ
MA1-135 was used in Binding experiments to identify a receptor for Osteolectin, integrin α11, which is expressed by Leptin Receptor positive cells and osteoblasts.
Fri Jan 11 00:00:00 EST 2019
Probing Morbillivirus Antisera Neutralization Using Functional Chimerism between Measles Virus and Canine Distemper Virus Envelope Glycoproteins.
Viruses
Muñoz-Alía MA,Russell SJ
MA1-135 was used in Flow cytometry/Cell sorting to shed further light on the factors constraining the evolution of new morbillivirus serotypes.
Sat Jul 27 00:00:00 EDT 2019
Probing Morbillivirus Antisera Neutralization Using Functional Chimerism between Measles Virus and Canine Distemper Virus Envelope Glycoproteins.
Viruses
Muñoz-Alía MA,Russell SJ
MA1-135 was used in Flow cytometry/Cell sorting to shed further light on the factors constraining the evolution of new morbillivirus serotypes.
Sat Jul 27 00:00:00 EDT 2019
Pyruvate kinase M2 is requisite for Th1 and Th17 differentiation.
JCI insight
Kono M,Maeda K,Stocton-Gavanescu I,Pan W,Umeda M,Katsuyama E,Burbano C,Orite SYK,Vukelic M,Tsokos MG,Yoshida N,Tsokos GC
MA1-135 was used in Immunoprecipitation to demonstrate that CaMK4 binds to PKM2 and promotes its activity, which is requisite for Th1 and Th17 differentiation.
Thu Jun 20 00:00:00 EDT 2019
CaMK4 compromises podocyte function in autoimmune and nonautoimmune kidney disease.
The Journal of clinical investigation
Maeda K,Otomo K,Yoshida N,Abu-Asab MS,Ichinose K,Nishino T,Kono M,Ferretti A,Bhargava R,Maruyama S,Bickerton S,Fahmy TM,Tsokos MG,Tsokos GC
MA1-135 was used in Immunoprecipitation to explore the role of Ca2+/calmodulin-dependent kinase signalling in podocytes.
Wed Aug 01 00:00:00 EDT 2018
Interaction between ROR1 and MuSK activation complex in myogenic cells.
FEBS letters
Karvonen H,Summala K,Niininen W,Barker HR,Ungureanu D
MA1-135 was used in Western blotting following immunoprecipitation to identify MuSK as a ROR1 as a new interacting partner for MuSK and Dok-7, which may have an important role in myogenic cell signalling.
Thu Feb 01 00:00:00 EST 2018
Interaction between ROR1 and MuSK activation complex in myogenic cells.
FEBS letters
Karvonen H,Summala K,Niininen W,Barker HR,Ungureanu D
MA1-135 was used in Western blotting following immunoprecipitation to identify MuSK as a ROR1 as a new interacting partner for MuSK and Dok-7, which may have an important role in myogenic cell signalling.
Thu Feb 01 00:00:00 EST 2018
Design of Peptoid-peptide Macrocycles to Inhibit the β-catenin TCF Interaction in Prostate Cancer.
Nature communications
Schneider JA,Craven TW,Kasper AC,Yun C,Haugbro M,Briggs EM,Svetlov V,Nudler E,Knaut H,Bonneau R,Garabedian MJ,Kirshenbaum K,Logan SK
Published figure using 6x-His Tag monoclonal antibody (Product # MA1-135) in ELISA
Tue Oct 23 00:00:00 EDT 2018
Towards synthetic cells using peptide-based reaction compartments.
Nature communications
Vogele K,Frank T,Gasser L,Goetzfried MA,Hackl MW,Sieber SA,Simmel FC,Pirzer T
Published figure using 6x-His Tag monoclonal antibody (Product # MA1-135) in Western Blot
Fri Sep 21 00:00:00 EDT 2018
A novel c-di-GMP binding domain in glycosyltransferase BgsA is responsible for the synthesis of a mixed-linkage β-glucan.
Scientific reports
Pérez-Mendoza D,Bertinetti D,Lorenz R,Gallegos MT,Herberg FW,Sanjuán J
MA1-135 was used in Dot blot to suggest that the cytoplasmic C-terminal domain of BgsA domain is important for both, c-di-GMP binding and glycosyltransferase activity of BgsA.
Mon Aug 21 00:00:00 EDT 2017
