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Product Details
80777-1-RR
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
Mammalian cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
7F14
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: PDDSGTFYDQ AVVSNDMEEH LEEPVAEPEP DPEPEPEQEP VSEIQEEKPE PVLEETAPED AQKSSSPAPA DIAQTVQEDL RTFSWASVTS KNLPPSGAVP VTGIPPHVVK VPASQPRPES KPESQIPPQR PQRDQRVREQ RINIPPQRGP RPIREAGEQG DIEPRRMVRH PDSHQLFIGN LPHEVDKSEL KDFFQSYGNV VELRINSGGK LPNFGFVVFD DSEPVQKVLS NRPIMFRGEV RLNVEEKKTR AAREGDRRDN RLRGPGGPRG GLGGGMRGPP RGGMVQKPGF GVGRGLAPRQ
Target Information
This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent DNA helicase VIII; DNA helicase VIII; G3BP-1; GAP binding protein; GAP SH3 domain-binding protein 1; GTPase activating protein (SH3 domain) binding protein 1; hDH VIII; MGC111040; Ras GTPase-activating protein-binding protein 1; Ras-GTPase-activating protein SH3-domain-binding protein; RasGAP-associated endoribonuclease G3BP
Gene Aliases: G3BP; G3BP1; HDH-VIII
UniProt ID: (Human) Q13283
Entrez Gene ID: (Human) 10146
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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