Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: LSGVDFQLRR GEKELLVPRS STSPDRIFFH LNAVALGDGG HYTCRYRLHD NQNGWSGDSA PVELILSDET LPAPEFSPEP ESGRALRLRC LAPLEGARFA LVREDRGGRR VHRFQSPAGT EALFELHNIS VADSANYSCV YVDLKPPFGG SAPSERLELH VDGPPPRPQL RATWSGAVLA GRDAVLRCEG PIPDVTFELL REGETKAVKT VRTPGAAANL ELIFVGPQHA GNYRCRYRSW VPHTFESELS DPVELLVAES; Positive Samples: SKOV3, HeLa, Mouse kidney, Rat liver
Alpha-1-B glycoprotein (A1BG) which is a plasma protein with no known function belongs to the immunoglobulin superfamily. Although the human A1BG has been known for four decades, and the information about the amino acid sequence, chromosomal assignment, and even genetic polymorphism in different populations have been known, no biological function has been suggested. A1BG (Mr approximately equal to 63,000) consists of one polypeptide chain of 474 amino acids with four glucosamine oligosaccharides. The polypeptide has five intrachain disulfide bonds and consists of five repeating structural domains, each containing about 95 amino acids and one disulfide bond. Recently human cysteine-rich secretory protein 3 (CRISP-3) has been found to be a binding partner of A1B, suggesting the A1BG-CRISP-3 complex displays a protecting function from a potentially harmful effect of free CRISP-3 in circulation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Alpha-1-B glycoprotein; alpha-1-B-glycoprotein; Alpha-1B-glycoprotein; alpha1B-glycoprotein; DKFZp686F0970; epididymis secretory sperm binding protein Li 163pA; HEL-S-163pA
Gene Aliases: A1B; A1BG; ABG; GAB; HYST2477
UniProt ID: (Human) P04217
Entrez Gene ID: (Human) 1
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