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The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. The encoded protein, which is a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor.
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Protein Aliases: alpha 14-galactosyltransferase; Alpha-1,4-galactosyltransferase; Alpha-1,4-N-acetylglucosaminyltransferase; Alpha4Gal-T1; cd77; CD77 synthase; GB3 synthase; Globotriaosylceramide synthase; lac; Lactosylceramide 4-alpha-galactosyltransferase; P blood group (P one antigen); P(k) antigen synthase; P1/Pk synthase; truncated alpha 1,4-galactosyltransferase; UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase
Gene Aliases: A14GALT; A4GALT; A4GALT1; Gb3S; P(k); P1; P1PK; PK
UniProt ID: (Human) Q9NPC4
Entrez Gene ID: (Human) 53947
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