Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: SAGIPELLS WLKQLQIKLH NPPTIHYQPS QGQMDLCVTS GSQQGLCKVF EMIINPGDNV LLDEPAYSGT LQSLHPLGCN IINVASDESG IVPDSLRDIL SRWKPEDAKN PQKNTPKFLY TVPNGNNPTG NSLTSERKKE IYELARKYDF LIIEDDPYYF LQFNKFRVPT FLSMDVDGRV IRADSFSKII SSGLRIGFLT GPKPLIERVI LHIQVSTLHP STFNQLMISQ LLHEWGEEGF MAHVDRVIDF YSNQKDAILA AADKWLTGLA EWHVPAAGMF LWIKVKGIND VKELIEEKAV KMGVLMLPGN AFYVDSSAPS PYLRASFSSA SPEQMDVAFQ VLAQLIKESL (81-429 aa encoded by BC031068)
This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; AadAT; Alpha-aminoadipate aminotransferase; Glycine transaminase AADAT; KAT/AadAT; kynurenine aminotransferase 2; Kynurenine aminotransferase II; Kynurenine--glyoxylate transaminase AADAT; kynurenine--oxoglutarate; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; Kynurenine--oxoglutarate transaminase II; Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; L kynurenine/alpha aminoadipate aminotransferase; Methionine--glyoxylate transaminase AADAT
Gene Aliases: AADAT; Aadt; AI875679; KAT2; KATII; KYAT2; mKat-2
UniProt ID: (Human) Q8N5Z0, (Mouse) Q9WVM8, (Rat) Q64602
Entrez Gene ID: (Human) 51166, (Mouse) 23923, (Rat) 29416
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