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AATK Antibody (PA5-104417) in ICC/IF
Immunocytochemistry analysis of AATK in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with AATK polyclonal antibody (Product # PA5-104417) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-104417
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human AATK(Accession Q6ZMQ8), corresponding to amino acid residues S523-A573.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2853723
Product Specific Information
Antibody detects endogenous levels of total LMTK1.
Target Information
The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AATYK; Apoptosis-associated tyrosine kinase; apoptosis-associated tyrosine kinase 1B; Brain apoptosis-associated tyrosine kinase; CDK5-binding protein; Lemur tyrosine kinase 1; p35-binding protein; p35BP; protein phosphatase 1, regulatory subunit 77; Serine/threonine-protein kinase LMTK1
Gene Aliases: AATK; AATYK; AATYK1; KIAA0641; LMR1; LMTK1; mKIAA0641; p35BP; PPP1R77
UniProt ID: (Human) Q6ZMQ8, (Mouse) Q80YE4
Entrez Gene ID: (Human) 9625, (Mouse) 11302
Performance Guarantee
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