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Product Details
PA5-92379
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 29-300 of human GABA transaminase (GABA transaminase (ABAT)) (NP_0011209201)
Conjugate
Form
Liquid
Concentration
1.04 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2806464
Product Specific Information
Immunogen sequence: SQAAAKVDVE FDYDGPLMKT EVPGPRSQEL MKQLNIIQNA EAVHFFCNYE ESRGNYLVDV DGNRMLDLYS QISSVPIGYS HPALLKLIQQ PQNASMFVNR PALGILPPEN FVEKLRQSLL SVAPKGMSQL ITMACGSCSN ENALKTIFMW YRSKERGQRG FSQEELETCM INQAPGCPDY SILSFMGAFH GRTMGCLATT HSKAIHKIDI PSFDWPIAPF PRLKYPLEEF VKENQQEEAR CLEEVEDLIV KYRKKKKTVA GIIVEPIQSE GG; Positive Samples: SW480, A375, Mouse liver, Mouse kidney, Mouse brain; Cellular Location: Mitochondrion matrix
Target Information
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: (S)-3-amino-2-methylpropionate transaminase; 4-aminobutyrate aminotransferase, mitochondrial; 4-aminobutyrate transaminase; beta-AlaAT I; beta-alanine oxoglutarate aminotransferase; FLJ17813; FLJ30272; GABA aminotransferase; GABA AT; GABA T; GABA transaminase; GABA transferase; GABA-AT; GABA-T; Gamma-amino-N-butyrate transaminase; hCG1984265; L AIBAT; L-AIBAT
Gene Aliases: 9630038C02Rik; ABAT; AI255750; beta-AlaAT; ENSMUSG00000051226; GABA-AT; Gabaat; GABAT; Gm9851; I54; Laibat; NPD009; X61497
UniProt ID: (Human) P80404, (Rat) P50554, (Mouse) P61922
Entrez Gene ID: (Human) 18, (Rat) 81632, (Mouse) 268860
4-aminobutyrate transaminase activity
pyridoxal phosphate binding
succinate-semialdehyde dehydrogenase binding
protein homodimerization activity
metal ion binding
(S)-3-amino-2-methylpropionate transaminase activity
iron-sulfur cluster binding
catalytic activity
transaminase activity
transferase activity
transaminase
response to hypoxia
aging
copulation
locomotory behavior
gamma-aminobutyric acid biosynthetic process
gamma-aminobutyric acid catabolic process
response to iron ion
negative regulation of gamma-aminobutyric acid secretion
cerebellum development
positive regulation of heat generation
positive regulation of insulin secretion
negative regulation of dopamine secretion
response to nicotine
exploration behavior
neurotransmitter catabolic process
response to drug
response to ethanol
negative regulation of blood pressure
positive regulation of dopamine metabolic process
behavioral response to cocaine
positive regulation of uterine smooth muscle contraction
negative regulation of platelet aggregation
positive regulation of inhibitory postsynaptic potential
positive regulation of prolactin secretion
positive regulation of aspartate secretion
response to cocaine
gamma-aminobutyric acid metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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