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Product Details
PA5-120484
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 140-350 of human ABCA2 (NP_001597.2).
Conjugate
Form
Liquid
Concentration
1.50 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914056
Product Specific Information
Positive test controls include: HeLa, Rat brain. The target is usually found in the following locations: Endosome membrane, Lysosome membrane, Multi-pass membrane protein.
Immunogen sequence: SHLDRSTVSS FSLDSVARNP QELWRFLTQN LSLPNSTAQA LLAARVDPPE VYHLLFGPSS ALDSQSGLHK GQEPWSRLGG NPLFRMEELL LAPALLEQLT CTPGSGELGR ILTVPESQKG ALQGYRDAVC SGQAAARARR FSGLSAELRN QLDVAKVSQQ LGLDAPNGSD SSPQAPPPRR LQALLGDLLD AQKVLQDVDV LSALALLLPQ G
Target Information
Probable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and neural development.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: abca2 {ECO:0000312|RGD:620238}; ATP-binding cassette 2; ATP-binding cassette sub-family A member 2; ATP-binding cassette transporter 2; ATP-binding cassette, sub-family A (ABC1), member 2; ATP-binding cassette, sub-family A, member 2
Gene Aliases: ABC2; ABCA2; AI413825; D2H0S1474E; KIAA1062; mKIAA1062
UniProt ID: (Human) Q9BZC7, (Rat) Q9ESR9
Entrez Gene ID: (Human) 20, (Mouse) 11305, (Rat) 79248
regulation of transcription from RNA polymerase II promoter
lipid metabolic process
transport
regulation of intracellular cholesterol transport
cholesterol efflux
phospholipid efflux
response to drug
cholesterol homeostasis
response to steroid hormone
transmembrane transport
lipid transport
cholesterol metabolic process
metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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