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Antibody detects endogenous levels of total ABCA8.
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extracellular and intracellular membranes by harnessing the energy of ATP hydrolysis. ABCA8 (ATP-binding cassette, sub-family A (ABC1), member 8) is a 1, 581 amino acid multi-pass membrane protein that contains two ABC transporter domains and belongs to the ABC transporter family. Expressed in a variety of tissues with particularly high expression in liver, heart and skeletal muscle, ABCA8 functions as an ATP-dependent lipophilic drug transporter that exists as multiple alternatively spliced isoforms.
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Protein Aliases: ABC-type organic anion transporter ABCA8; ABC-type organic anion transporter ABCA8A; ABC-type organic anion transporter ABCA8B; ATP-binding cassette sub-family A member 8; ATP-binding cassette sub-family A member 8-A; ATP-binding cassette sub-family A member 8-B; ATP-binding cassette sub-family A member 8A; ATP-binding cassette sub-family A member 8B; ATP-binding cassette, sub-family A (ABC1), member 8
Gene Aliases: ABCA8; Abca8a; Abca8b; KIAA0822
UniProt ID: (Human) O94911, (Mouse) Q8K442, (Mouse) Q8K440
Entrez Gene ID: (Human) 10351, (Mouse) 217258, (Mouse) 27404
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