Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 1
ABCA8 Antibody (PA5-120749) in WB
Western blot analysis of ABCA8 in extracts of various cell lines. Samples were incubated with ABCA8 Polyclonal antibody (Product # PA5-120749) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
Product Details
PA5-120749
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 425-495 of human ABCA8 (NP_009099.1).
Conjugate
Form
Liquid
Concentration
2.17 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914321
Product Specific Information
Positive test controls include: HeLa, HepG2, U-251MG.
Immunogen sequence: NEYGHRRPPL FFLKSSFWSQ TQKTDHVALE DEMDADPSFH DSFEQAPPEF QGKEAIRIRN VTKEYKGKPD K
Target Information
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extracellular and intracellular membranes by harnessing the energy of ATP hydrolysis. ABCA8 (ATP-binding cassette, sub-family A (ABC1), member 8) is a 1, 581 amino acid multi-pass membrane protein that contains two ABC transporter domains and belongs to the ABC transporter family. Expressed in a variety of tissues with particularly high expression in liver, heart and skeletal muscle, ABCA8 functions as an ATP-dependent lipophilic drug transporter that exists as multiple alternatively spliced isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: ABC-type organic anion transporter ABCA8; ATP-binding cassette sub-family A member 8; ATP-binding cassette sub-family A member 8-A; ATP-binding cassette, sub-family A (ABC1), member 8; ATP-binding cassette, sub-family A (ABC1), member 8a; ATP-binding cassette, sub-family A (ABC1), member 8b; ATP-binding cassette, subfamily A (ABC1), member 8
Gene Aliases: ABCA8; Abca8b; KIAA0822
UniProt ID: (Human) O94911
Entrez Gene ID: (Human) 10351, (Rat) 303637, (Rat) 303638
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support