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Product Details
14996-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ABCB6 Fusion Protein Ag6982 (556-842 aa encoded by BC000559)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: TNFIDMENM FDLLKEETEV KDLPGAGPLR FQKGRIEFEN VHFSYADGRE TLQDVSFTVM PGQTLALVGP SGAGKSTILR LLFRFYDISS GCIRIDGQDI SQVTQASLRS HIGVVPQDTV LFNDTIADNI RYGRVTAGND EVEAAAQAAG IHDAIMAFPE GYRTQVGERG LKLSGGEKQR VAIARTILKA PGIILLDEAT SALDTSNERA IQASLAKVCA NRTTIVVAHR LSTVVNADQI LVIKDGCIVE RGRHEALLSR GGVYADMWQL QQGQEETSED TKPQTMER (556-842 aa encoded by BC000559)
Target Information
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ABC-type heme transporter ABCB6; ATP-binding cassette half-transporter; ATP-binding cassette sub-family B member 6; ATP-binding cassette sub-family B member 6, mitochondrial; ATP-binding cassette, sub-family B (MDR/TAP), member 6; ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group); EST45597; FLJ22414; Mitochondrial ABC transporter 3; Mt-ABC transporter 3; P-glycoprotein-related protein; Ubiquitously-expressed mammalian ABC half transporter
Gene Aliases: 1200005B17Rik; ABC; ABC14; ABCB6; DUH3; LAN; MCOPCB7; MTABC3; PRP; PSHK2; UMAT
UniProt ID: (Human) Q9NP58, (Rat) O70595, (Mouse) Q9DC29
Entrez Gene ID: (Human) 10058, (Rat) 140669, (Mouse) 74104
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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