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The antibody detects endogenous level of total ABCB8 protein.
This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ABCB8; ATP-binding cassette sub-family B member 8, mitochondrial; ATP-binding cassette, sub-family B (MDR/TAP), member 8; M-ABC1; mitochondrial ABC protein; Mitochondrial ATP-binding cassette 1; Mitochondrial potassium channel ATP-binding subunit; Mitochondrial sulfonylurea-receptor; MITOSUR
Gene Aliases: ABCB8; EST328128; M-ABC1; MABC1; MITOSUR
UniProt ID: (Human) Q9NUT2
Entrez Gene ID: (Human) 11194
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