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Immunogen sequence: LFRVGIRGGP FPGRLLPPLR FQTFSAVRYS DGYRSSSLLR AVAHLRSQLW AHLPRAPLAP RWSPSAWCWV GGALLGPMVL SKHPHLCLVA LCEAEEAPPA SSTPHVVGSR FNWKLFWQFL
Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 65%.
This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants.
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Protein Aliases: ABCB8; ATP-binding cassette sub-family B member 8, mitochondrial; ATP-binding cassette, sub-family B (MDR/TAP), member 8; M-ABC1; mitochondrial ABC protein; Mitochondrial ATP-binding cassette 1; Mitochondrial potassium channel ATP-binding subunit; Mitochondrial sulfonylurea-receptor; MITOSUR
Gene Aliases: ABCB8; EST328128; M-ABC1; MABC1; MITOSUR
UniProt ID: (Human) Q9NUT2
Entrez Gene ID: (Human) 11194
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