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Product Details
18138-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ABCD1 Fusion Protein Ag12757 (358-745 aa encoded by BC025358)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SESDAEAVK KAALEKKEEE LVSERTEAFT IARNLLTAAA DAIERIMSSY KEVTELAGYT ARVHEMFQVF EDVQRCHFKR PRELEDAQAG SGTIGRSGVR VEGPLKIRGQ VVDVEQGIIC ENIPIVTPSG EVVVASLNIR VEEGMHLLIT GPNGCGKSSL FRILGGLWPT YGGVLYKPPP QRMFYIPQRP YMSVGSLRDQ VIYPDSVEDM QRKGYSEQDL EAILDVVHLH HILQREGGWE AMCDWKDVLS GGEKQRIGMA RMFYHRPKYA LLDECTSAVS IDVEGKIFQA AKDAGIALLS ITHRPSLWKY HTHLLQFDGE GGWKFEKLDS AARLSLTEEK QRLEQQLAGI PKMQRRLQEL CQILGEAVAP AHVPAPSPQG PGGLQGAST (358-745 aa encoded by BC025358)
Target Information
This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Adrenoleukodystrophy protein; ALDP; ATP-binding cassette sub-family D member 1; ATP-binding cassette, sub-family D (ALD), member 1
Gene Aliases: ABC42; ABCD1; ALD; ALDP; AMN
UniProt ID: (Human) P33897
Entrez Gene ID: (Human) 215
transporter activity
long-chain fatty acid transporter activity
peroxisomal fatty-acyl-CoA transporter activity
protein binding
ATP binding
ATPase activity
enzyme binding
ATPase activity, coupled to transmembrane movement of substances
identical protein binding
protein homodimerization activity
ATP-binding cassette (ABC) transporter
fatty acid beta-oxidation
peroxisome organization
peroxisomal long-chain fatty acid import
peroxisomal membrane transport
fatty acid beta-oxidation using acyl-CoA oxidase
alpha-linolenic acid metabolic process
long-chain fatty acid catabolic process
very long-chain fatty acid catabolic process
linoleic acid metabolic process
transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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