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Invitrogen
ABCD1 Recombinant Rabbit Monoclonal Antibody (23GB3125)
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 2
ABCD1 Antibody (MA5-53354) in WB
Western Blot analysis of ABCD1. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with ABCD1 recombinant monoclonal antibody (Product # MA5-53354) with a dilution of 1:5,000, followed by HRP-conjugated goat anti-rabbit secondary antibody with a dilution of 1:20,000. Image was developed using FeQTM ECL Substrate Kit.
Product Details
MA5-53354
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB3125
Immunogen
A synthetic peptide of human ABCD1/ALD (650-745AA).
Conjugate
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adrenoleukodystrophy protein; ALDP; ATP-binding cassette sub-family D member 1; ATP-binding cassette, sub-family D (ALD), member 1; ATP-binding cassette, sub-family D, member 1; X-linked adrenoleukodystrophy (ALD) gene homolog
Gene Aliases: ABC42; ABCD1; ALD; Aldgh; ALDP; AMN; RGD1562128
UniProt ID: (Human) P33897, (Mouse) P48410, (Rat) D3ZHR2
Entrez Gene ID: (Human) 215, (Mouse) 11666, (Rat) 363516
transporter activity
long-chain fatty acid transporter activity
peroxisomal fatty-acyl-CoA transporter activity
protein binding
ATP binding
ATPase activity
enzyme binding
ATPase activity, coupled to transmembrane movement of substances
identical protein binding
protein homodimerization activity
nucleotide binding
ATP-binding cassette (ABC) transporter
fatty acid beta-oxidation
peroxisome organization
peroxisomal long-chain fatty acid import
peroxisomal membrane transport
fatty acid beta-oxidation using acyl-CoA oxidase
alpha-linolenic acid metabolic process
long-chain fatty acid catabolic process
very long-chain fatty acid catabolic process
linoleic acid metabolic process
transmembrane transport
transport
fatty-acyl-CoA transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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