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ABCD1 Antibody (CF803560) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ABCD1 (RC206885, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ABCD1. Positive lysates LY424967 (100 µg) and LC424967 (20 µg) can be purchased separately from OriGene.
Product Details
CF803560
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI2E9
Immunogen
Human recombinant protein fragment corresponding to amino acids 508-745 of human ABCD1 produced in E.coli.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adrenoleukodystrophy protein; ALDP; ATP-binding cassette sub-family D member 1; ATP-binding cassette, sub-family D (ALD), member 1
Gene Aliases: ABC42; ABCD1; ALD; ALDP; AMN
UniProt ID: (Human) P33897
Entrez Gene ID: (Human) 215
transporter activity
long-chain fatty acid transporter activity
peroxisomal fatty-acyl-CoA transporter activity
protein binding
ATP binding
ATPase activity
enzyme binding
ATPase activity, coupled to transmembrane movement of substances
identical protein binding
protein homodimerization activity
ATP-binding cassette (ABC) transporter
fatty acid beta-oxidation
peroxisome organization
peroxisomal long-chain fatty acid import
peroxisomal membrane transport
fatty acid beta-oxidation using acyl-CoA oxidase
alpha-linolenic acid metabolic process
long-chain fatty acid catabolic process
very long-chain fatty acid catabolic process
linoleic acid metabolic process
transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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