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ABCD2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters.
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Protein Aliases: adrenoleukodystrophy related; Adrenoleukodystrophy-like 1; Adrenoleukodystrophy-related protein; ATP-binding cassette sub-family D member 2; ATP-binding cassette, sub-family D (ALD), member 2; hALDR
Gene Aliases: ABC39; ABCD2; ALD1; ALDL1; ALDR; ALDRP; hALDR
UniProt ID: (Human) Q9UBJ2, (Mouse) Q61285, (Rat) Q9QY44
Entrez Gene ID: (Human) 225, (Mouse) 26874, (Rat) 84356
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