Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: NHLDIETIDA LADAINEFEG GMMLVSHDFR LIQQVAQEIW VCEKQTITKW PGDILAYKEH LKSKLVDEEP QLTKRTHNVC TLTLASLPRP
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 88%.
OCIAD1 was identified via immunoscreening of an ovarian carcinoma cDNA library from ovarian cancer patients and is expressed in multiple tissues including ovary, placenta, brain, testis, prostate, and mammary gland. Two isoforms of OCIAD1 are known to exist; the shorter isoform is restricted to the central nervous system. OCIAD1 is a transmembrane protein whose overexpression in HEY ovarian cancer cells increased lysophosphatidic acid- (LPA-)induced, but not basal level cell adhesion to extracellular matrix proteins collagen I and laminin10/11. This adhesion is not blocked by LY294002 and GF109203X, suggesting that OCIAD1 does not use protein kinase C and PI3 kinase signaling pathways to exert its effect on adhesion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ABC-type transport protein; ATP-binding cassette sub-family F member 2; ATP-binding cassette, sub-family F (GCN20), member 2; DKFZp586K1823; Iron-inhibited ABC transporter 2
Gene Aliases: ABC28; ABCF2; EST133090; HUSSY-18; HUSSY18
UniProt ID: (Human) Q9UG63
Entrez Gene ID: (Human) 10061
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