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ABHD12 Antibody (PA5-116765) in WB
Western blot analysis of ABHD12 in extracts of various cell lines. Samples were incubated with ABHD12 Polyclonal antibody (Product # PA5-116765) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Product Details
PA5-116765
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 110-250 of human ABHD12 (NP_0564151)
Conjugate
Form
Liquid
Concentration
1.35 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2901396
Product Specific Information
Positive Samples: Rat brain, Rat pancreas
Immunogen sequence: YFIDLKKPQD QGLNHTCNYY LQPEEDVTIG VWHTVPAVWW KNAQGKDQMW YEDALASSHP IILYLHGNAG TRGGDHRVEL YKVLSSLGYH VVTFDYRGWG DSVGTPSERG MTYDALHVFD WIKARSGDNP VYIWGHSLGT G
Target Information
This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol, the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC, resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2-arachidonoylglycerol hydrolase; 2-arachidonoylglycerol hydrolase ABHD12; Abhydrolase domain-containing protein 12; DKFZP434P106; hABHD12; Lysophosphatidylserine lipase ABHD12; Monoacylglycerol lipase ABHD12; Oxidized phosphatidylserine lipase ABHD12
Gene Aliases: ABHD12; ABHD12A; BEM46L2; C20orf22; dJ965G21.2; PHARC
UniProt ID: (Human) Q8N2K0, (Rat) Q6AYT7
Entrez Gene ID: (Human) 26090, (Rat) 499913
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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