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Product Details
PA5-55445
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ABHD12. Recombinant protein control fragment (Product #RP-90030).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2637548
Product Specific Information
Immunogen sequence: ALILESPFTN IREEAKSHPF SVIYRYFPGF DWFFLDPITS SGIKFANDEN VKHISCPLLI LHAEDDPVVP FQLGRKLYSI AAPARSFRDF KVQFVPFHSD LGYRHKYIYK SPELPRILRP
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
Target Information
This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol, the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC, resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2-arachidonoylglycerol hydrolase; 2-arachidonoylglycerol hydrolase ABHD12; Abhydrolase domain-containing protein 12; DKFZP434P106; hABHD12; Lysophosphatidylserine lipase ABHD12; Monoacylglycerol lipase ABHD12; Oxidized phosphatidylserine lipase ABHD12
Gene Aliases: ABHD12; ABHD12A; BEM46L2; C20orf22; dJ965G21.2; PHARC
UniProt ID: (Human) Q8N2K0
Entrez Gene ID: (Human) 26090
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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