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Product Details
PA5-52734
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ABHD3. Recombinant protein control fragment (Product #RP-90347).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2637557
Product Specific Information
Immunogen sequence: KKPQLVTGGE SFSRFLQDHC PVVTETYYPT VWCWEGRGQT LLRPFITSKP PVQYRNELIK TADGGQISLD WFDNDNSTCY MDASTRPTIL LLPGLTGTSK ESYILHMIHL SEELGYRCVV FNNRGVAGEN LLTPRTYCCA NTEDLE
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
Target Information
The α/β hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical α/β hydrolase fold, which consists of an eight stranded parallel α/β structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer's disease, obesity and blood clotting disorders. The α/β hydrolase domain containing (ABHD) gene subfamily is comprised of 15 mostlyuncharacterized members, most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD1 plays a role in metabolizing smoking xenobiotics. ABHD2 participates in the development of atherosclerosis. ABHD3 is a 409 amino acid single-pass type II membrane protein. ABHD4 is involved in an alternative synthesis pathway of NAE (N-acyl ethanolamine). Mutations in ABHD5 contribute to Chanarin-Dorfman syndrome. ABDH6 may play a role in nervous system metabolism and signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Abhydrolase domain-containing protein 3; alpha/beta hydrolase domain containing protein 3; lung alpha/beta hydrolase 3; Phospholipase ABHD3
Gene Aliases: ABHD3; LABH3
UniProt ID: (Human) Q8WU67
Entrez Gene ID: (Human) 171586
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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