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Product Details
PA5-68077
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human ABHD3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2691640
Product Specific Information
Predicted to react with Mouse samples.
Target Information
The α/β hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical α/β hydrolase fold, which consists of an eight stranded parallel α/β structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer's disease, obesity and blood clotting disorders. The α/β hydrolase domain containing (ABHD) gene subfamily is comprised of 15 mostlyuncharacterized members, most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD1 plays a role in metabolizing smoking xenobiotics. ABHD2 participates in the development of atherosclerosis. ABHD3 is a 409 amino acid single-pass type II membrane protein. ABHD4 is involved in an alternative synthesis pathway of NAE (N-acyl ethanolamine). Mutations in ABHD5 contribute to Chanarin-Dorfman syndrome. ABDH6 may play a role in nervous system metabolism and signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Abhydrolase domain-containing protein 3; alpha/beta hydrolase domain containing protein 3; Lung alpha/beta hydrolase 3; MmLABH3; Phospholipase ABHD3
Gene Aliases: AA675331; ABHD3; LABH3
UniProt ID: (Human) Q8WU67, (Mouse) Q91ZH7
Entrez Gene ID: (Human) 171586, (Mouse) 106861
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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