Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: TIGPAAPGS APGSQYGTMT RQISRHNSTT SSTSSGGYRR TPSVTAQFSA QPHVNGGPLY SQNSISIAPP PPPMPQLTPQ IPLTGFVARV QENIADSPTP PPPPPPDDIP MFDDSP (265-379 aa encoded by BC024254)
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity. Alternative splice variants that encode different isoforms have been found for this gene.
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Protein Aliases: Abelson interactor 1; Abi-1; Abl interactor 1; Abl-binding protein 4; abl-interactor 1; Abl-interactor protein 1 long; AblBP4; Ablphilin-1; e3B1; EL2; eps8 binding protein; Eps8 SH3 domain-binding protein; Eps8-binding protein; HS3; interactor protein AblBP4; nap1 binding protein; Nap1-binding protein; Nap1BP; spectrin SH3 domain binding protein 1; Spectrin SH3 domain-binding protein 1; SPH3; SPTA
Gene Aliases: ABI-1; ABI1; ABLBP4; E3B1; NAP1; NAP1BP; SSH3BP; SSH3BP1
UniProt ID: (Human) Q8IZP0, (Mouse) Q8CBW3
Entrez Gene ID: (Human) 10006, (Mouse) 11308
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