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ABI1 Antibody (A301-196A) in IP
Detection of human ABI1 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-ABI1 antibody A301-196A used for IP at 3 µg/mg lysate. ABI1 was also immunoprecipitated by rabbit anti-ABI1 antibodies A301-195A and A301-197A, which recognize other epitopes. For blotting immunoprecipitated ABI1, A301-197A was used at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
Product Details
A301-196A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 225 and 275 of human abl-interactor 1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Wet ice
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
Target Information
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity. Alternative splice variants that encode different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Abelson interactor 1; Abi-1; Abl interactor 1; Abl-binding protein 4; abl-interactor 1; Abl-interactor protein 1 long; AblBP4; e3B1; EL2; Eps8 SH3 domain-binding protein; Eps8-binding protein; HS3; interactor protein AblBP4; nap1 binding protein; Nap1-binding protein; Nap1BP; Spectrin SH3 domain-binding protein 1; SPH3; SPTA
Gene Aliases: ABI-1; ABI1; ABLBP4; E3B1; NAP1BP; SSH3BP; SSH3BP1
UniProt ID: (Human) Q8IZP0
Entrez Gene ID: (Human) 10006
somitogenesis
movement of cell or subcellular component
transmembrane receptor protein tyrosine kinase signaling pathway
actin polymerization or depolymerization
negative regulation of cell proliferation
viral process
peptidyl-tyrosine phosphorylation
megakaryocyte development
Fc-gamma receptor signaling pathway involved in phagocytosis
vascular endothelial growth factor receptor signaling pathway
positive regulation of protein tyrosine kinase activity
lamellipodium morphogenesis
cell-cell adhesion
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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