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This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified.
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Protein Aliases: abLIM-1; Actin-binding double zinc finger protein; actin-binding double-zinc-finger protein; Actin-binding LIM protein 1; Actin-binding LIM protein family member 1; LIMAB1; Limatin
Gene Aliases: 2210411C18Rik; 2610209L21Rik; 4833406P10Rik; 9330196J19Rik; ABLIM; abLIM-1; ABLIM1; AV079770; AW060987; AW215784; KIAA0059; LIMAB1; LIMATIN; mKIAA0059; RGD1565768
UniProt ID: (Human) O14639, (Mouse) Q8K4G5
Entrez Gene ID: (Human) 3983, (Rat) 307989, (Mouse) 226251
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