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Product Details
PA5-113898
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the middle region of Mouse Abo (aa 200-249)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2884413
Product Specific Information
Immunogen sequence: GVEILSTFFG TLHPGFYSSS REAFTYERRP QSQAYIPWDR GDFYYGGAFF
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Human: 100%; Rat: 100%
Target Information
Histo-blood group ABO system transferase (NAGAT) is a member of the glycosyltransferase 6 family of proteins and the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B and H; the NAGAT protein functions as the basis of this group. A, B and AB individuals express a glycosyltransferase activity converting the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), while O individuals do not express this glycosyltransferase activity. The B phenotype of NAGAT differs from the A form by a few residue substitutions, whereas the O form is a result of a single base frame-shift deletion in the N-terminal extremity of the gene. The NAGAT protein localizes to the Golgi apparatus and its conserved DXD motif functions in cofactor binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A transferase; B (A) alpha 1; B transferase; BGAT; Cis-AB transferase; Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; Histo-blood group A transferase; Histo-blood group ABO system transferase; Histo-blood group B transferase; NAGAT
Gene Aliases: Abo; NAGAT
UniProt ID: (Mouse) P38649
Entrez Gene ID: (Mouse) 80908
alpha-1,3-galactosyltransferase activity
glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity
fucosylgalactoside 3-alpha-galactosyltransferase activity
transferase activity
transferase activity, transferring glycosyl groups
transferase activity, transferring hexosyl groups
metal ion binding
glycosyltransferase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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