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Product Details
PA5-27079
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region within amino acids 797 and 859 of Human ABR
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2544555
Product Specific Information
Recommended positive controls: A431, mouse brain.
Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis, suggesting that Rho-related GTPases help coordinate motor skills and balance. Alternatively spliced transcript variants that encode different isoforms have been reported for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Active breakpoint cluster region-related protein
Gene Aliases: ABR; MDB
UniProt ID: (Human) Q12979, (Mouse) Q5SSL4
Entrez Gene ID: (Human) 29, (Mouse) 109934
negative regulation of cellular extravasation
small GTPase mediated signal transduction
brain development
actin cytoskeleton organization
response to lipopolysaccharide
regulation of Rho protein signal transduction
inner ear morphogenesis
positive regulation of apoptotic process
regulation of vascular permeability
negative regulation of neutrophil degranulation
positive regulation of GTPase activity
negative regulation of inflammatory response
positive regulation of phagocytosis
neuromuscular process controlling balance
regulation of small GTPase mediated signal transduction
negative regulation of blood vessel remodeling
signal transduction
negative regulation of cell migration
intracellular signal transduction
Performance Guarantee
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